Threading Zmax Znorm MUSTER 3.50 0.60 dPPAS 8.31 0.89 wdPPAS 6.23 0.67 wMUSTER 3.85 0.66 wPPAS 4.33 0.62 dPPAS2 10.37 0.99 PPAS 4.27 0.61 Env-PPAS 5.89 0.74 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.55 0.42+-0.14 11.3+-4.5 10605 0.108 model2 -3.07 6158 0.064 model3 -3.62 3379 0.037 model4 -5.00 310 0.003 model5 -5.00 223 0.005 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).