I-TASSER results

Input Sequence in FASTA format

>protein (143 residues)
MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGV
TICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAE
LLNAADTLDDGRRQLDDLGEHRR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 \| \| \| \| \| \| \| MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGVTICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAELLNAADTLDDGRRQLDDLGEHRR
Prediction	CCCCCCCCCEEHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEEHCCCCCCEEEEEEHCCCEEEHCEEEEHCCCCHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
Conf.Score	99888886444446888998765444434445889999999999986689999998698678876556478886445677764665665557764776444789866777556555555545455555578899988876669
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 \| \| \| \| \| \| \| MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGVTICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAELLNAADTLDDGRRQLDDLGEHRR
Prediction	76444543110131446454231313541373356444342164435411540274231120031143144543201311112544325343144432142442212233452454124321514432553454256336568
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140

                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCEEHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEEHCCCCCCEEEEEEHCCCEEEHCEEEEHCCCCHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
MTTTPRQPLFCAHADTNGDPGRCACGQQLADVGPATPPPPWCEPGTEPIWEQLTERYGGVTICQWTRYFPAGDPVAADVWIAADDRVVDGRVLRTQPAIHYTEPPVLGIGPAAARRLAAELLNAADTLDDGRRQLDDLGEHRR

3wtdA

0.21

0.18

0.87

0.88

MUSTER

------SPPLCTLPPGPEPPRVCYCEGEGFNLYVTDAAELWSTCFTPDSLAALKARFGLEDITPRFRACEQQA-----VALTLQEDRASLTLSGGPSALAFDLSKV--PGPEAAPRLRALTLGLAKRVWSLERRLAAA-----

3wtdA

0.20

0.17

0.83

0.76

dPPAS

------SPPLCTLPPGPEPPRFCYCEGEGFNLYVTDAAELWSTCFTPDSLAALKARFGLEDICEQQAVALTLQEDRASLTLSGGPSALAFDLSKVP-------------GPEAAPRLRALTLGLAKRVWSLERRLAAA-----

3wtdA

0.25

0.20

0.83

0.62

wdPPAS

------SPPLCTLPPGPEPP-RCYCEGEGFNLYVTDAAELWSTCFTPDSLAALKARFGLEDI---PRFCEQQA-----VALTLEDRASL-TLSGGPSALAFDKVP----GPEAAPRLRALTLGLAKRVWSLERRLAAA-----

3wtdA

0.27

0.22

0.80

0.75

wMUSTER

-------PPLCTLPPGPEPP-RCYCEGELYVTDAAE----WSTCFTPDSLAALKARFGLEDI--TPRFCEQQA-----VALTLEDRASL-TLSGGPSALAFSKVP----GPEAAPRLRALTLGLAKRVWSLERRLAAA-----

3ia1A

0.33

0.23

0.69

0.49

wPPAS

-AVKPGEPLF---LDPKGQP-------TPATVSPAS----WCTV--EPGLHRVAEETGVISR-VVLEYM-YPRPLLASD----RDR--PHEV-----AARF----VLGQ-PW-VALFAG-RAG-REALLDALLLA-DL-----

1x4aA

0.25

0.16

0.64

0.70

dPPAS2

--------------GSSGSSGMSGGGVI---RGPAGNNPPDI---RTKDIEDVFYKYGAIRDIDLNRRGGPPDPRDAEDAVYGDGYDYDGYRLRVEFP---RSGRGTGSGPSSG-----------------------------

3wtdA

0.25

0.21

0.85

0.70

PPAS

------SPPLCTLPPGPEPP-RCYCEGEGFNLYVTDAAELWSTCFTPDSLAALKARFGLEDI---PRFRAACEQQAVALTLQ-EDRASL-TLSGGPSALAFDKVP----GPEAAPRLRALTLGLAKRVWSLERRLAAA-----

3tr8A

0.25

0.24

0.97

0.79

Env-PPAS

NADFSDDNLIWLDLETGLDPERDATNSHLLAEGPAFQPDNWNASGLERVKNSVDEVEATLTLAFLEKYVSAGKSPLCGNSVCQDRRFLS-RYPRLNQFFHY---RVTTL-KILAQRWAPQIAAAHIALQDIRDSIEELRYYRA

1su2A

0.16

0.15

0.94

0.72

MUSTER

MDERTHVPVAAGVVLLNER-GDILLVQEKGIPGHPEKAGLWHEDGQDAAVREACEETGVKFLGAYLGRFPDGVLILRHVWLA---EPEPG-----QTLAPAFTDEIAEASFVSREDFAQLYAAGQIRMYQTKLFYADALREKG

1wf1A

0.20

0.13

0.68

0.67

dPPAS

--------------GSSGSSGMSLKLQASNVTNKNDPKSINSALVKKSDVETIFSKYGRVAGCSVHKGYAYSNERHARAAVLGNGRVLAGQTLDINMA---GEPKPDRSGPSSG-----------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.83

Estimated TM-score = 0.49±0.15

Estimated RMSD = 8.6±4.5Å

Download Model 2

C-score=-3.77

Download Model 3

C-score=-4.44

Download Model 4

C-score=-3.05

Download Model 5

C-score=-4.65

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3wtdA	0.719	2.46	0.202	0.867
2	2qm4A	0.548	3.85	0.120	0.811
3	1ik9A	0.546	4.31	0.061	0.888
4	3q0xA	0.540	3.92	0.050	0.797
5	5al7A	0.534	3.71	0.037	0.769
6	2y3vA	0.533	3.51	0.095	0.769
7	5chxA	0.517	4.39	0.047	0.860
8	4ckmA	0.494	3.58	0.106	0.692
9	3jv1A	0.489	3.95	0.028	0.727
10	3pyiB	0.471	3.48	0.038	0.664

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.05	3	3mpjD	FAD	Rep, Mult	25,27,28,32,44,115,116,118,119
2	0.05	3	3i8gW	MG	Rep, Mult	113,117
3	0.05	3	2d44A	UUU	Rep, Mult	24,25,26,32,68,91
4	0.05	3	3p2aA	ZN	Rep, Mult	11,14,23,25
5	0.03	2	1m57H	HEA	Rep, Mult	9,124,128
6	0.03	2	4kt0F	CLA	Rep, Mult	117,121
7	0.03	2	2nwxB	ASP	Rep, Mult	34,35,36,37,38,39,41,113,116,117,120
8	0.02	1	2z4rA	MG	Rep, Mult	46,84,85
9	0.02	1	1s5ld	CLA	Rep, Mult	1,134
10	0.02	1	1sumB	FE	Rep, Mult	126,130
11	0.02	1	2y04B	2CV	Rep, Mult	122,123
12	0.02	1	3c67A	GLC	Rep, Mult	73,78,80,89,94
13	0.02	1	3g2fA	MG	Rep, Mult	17,19
14	0.02	1	1wd4A	AHR	Rep, Mult	4,7,126,127,134
15	0.02	1	1ik9B	III	Rep, Mult	48,49,51,52,55,56
16	0.02	1	4f0pB	MG	Rep, Mult	43,73,96,98
17	0.02	1	2i6kA	MG	Rep, Mult	25,43
18	0.02	1	2nwwC	TB1	Rep, Mult	20,21,121,124,125,128
19	0.02	1	3e27A	MG	Rep, Mult	73,86

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1gjqA	0.429	4.51	0.044	0.685	1.7.99.1,1.7.2.1	NA
2	0.060	2ix6A	0.426	4.75	0.073	0.699	1.3.3.6	NA
3	0.060	1siqA	0.424	4.86	0.055	0.720	1.3.99.7	NA
4	0.060	1q9hA	0.435	4.91	0.074	0.783	3.2.1.91	NA
5	0.060	1ukwA	0.424	4.48	0.111	0.692	1.3.99.3	NA
6	0.060	1y2mB	0.424	4.42	0.100	0.678	4.3.1.24	116
7	0.060	1b8fA	0.437	4.00	0.105	0.636	4.3.1.3	NA
8	0.060	1is2A	0.428	4.90	0.044	0.776	1.3.3.6	18
9	0.060	1qwlA	0.429	5.06	0.021	0.762	1.11.1.6	NA
10	0.060	1hbmB	0.427	4.35	0.040	0.699	2.8.4.1	NA
11	0.060	2rgzB	0.440	4.28	0.020	0.657	1.14.99.3	124
12	0.060	2fonB	0.481	4.50	0.072	0.762	1.3.3.6	NA
13	0.060	1lf6A	0.478	4.57	0.022	0.776	3.2.1.3	NA
14	0.060	1aomB	0.429	4.28	0.052	0.678	1.7.99.1,1.7.2.1	NA
15	0.060	1yrzA	0.429	5.03	0.056	0.748	3.2.1.37	75
16	0.060	1w07B	0.426	4.84	0.051	0.727	1.3.3.6	7
17	0.060	1rx0A	0.437	4.83	0.107	0.727	1.3.99.-	NA
18	0.060	1mroB	0.427	4.33	0.040	0.699	2.8.4.1	NA
19	0.060	2ebsB	0.435	4.17	0.053	0.678	3.2.1.150	9,89

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.30	0.741	2.51	0.19	0.90	3wtdB	GO:0005634 GO:0006281 GO:0006303 GO:0006974 GO:0032947 GO:0035861 GO:0042803 GO:0043564 GO:0051103 GO:0070062 GO:0070419
1	0.09	0.551	4.20	0.04	0.87	4xa4A	GO:0000146 GO:0000166 GO:0000793 GO:0001725 GO:0002026 GO:0002027 GO:0003009 GO:0003677 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005859 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006936 GO:0006941 GO:0006974 GO:0007512 GO:0008022 GO:0010165 GO:0014728 GO:0014883 GO:0016459 GO:0016874 GO:0016887 GO:0016925 GO:0030016 GO:0030017 GO:0030018 GO:0030049 GO:0030054 GO:0030898 GO:0031449 GO:0032807 GO:0032982 GO:0042803 GO:0046034 GO:0046982 GO:0051103 GO:0051351 GO:0055010 GO:0060048 GO:0070419 GO:0071285 GO:0075713
2	0.08	0.497	4.55	0.08	0.81	2y3wA	GO:0000280 GO:0005737 GO:0005813 GO:0005814 GO:0005815 GO:0005856 GO:0007049 GO:0007052 GO:0007099 GO:0007283 GO:0040016 GO:0051298 GO:0098536
3	0.07	0.546	4.31	0.06	0.89	1ik9A	GO:0000793 GO:0003677 GO:0005634 GO:0005654 GO:0005813 GO:0005829 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006974 GO:0008022 GO:0010165 GO:0016874 GO:0016925 GO:0030054 GO:0032807 GO:0051103 GO:0051351 GO:0070419 GO:0071285 GO:0075713
4	0.07	0.534	4.13	0.06	0.85	5cj4C	GO:0000146 GO:0000166 GO:0000793 GO:0001725 GO:0002026 GO:0002027 GO:0003009 GO:0003677 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005859 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006936 GO:0006941 GO:0006974 GO:0007512 GO:0008022 GO:0010165 GO:0014728 GO:0014883 GO:0016459 GO:0016874 GO:0016887 GO:0016925 GO:0030016 GO:0030017 GO:0030018 GO:0030049 GO:0030054 GO:0030898 GO:0031449 GO:0032807 GO:0032982 GO:0042803 GO:0046034 GO:0046982 GO:0051103 GO:0051351 GO:0055010 GO:0060048 GO:0070419 GO:0071285 GO:0075713
5	0.07	0.546	4.44	0.05	0.88	5cj0A	GO:0000146 GO:0000166 GO:0000793 GO:0001725 GO:0002026 GO:0002027 GO:0003009 GO:0003677 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005859 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006936 GO:0006941 GO:0006974 GO:0007512 GO:0008022 GO:0010165 GO:0014728 GO:0014883 GO:0016459 GO:0016874 GO:0016887 GO:0016925 GO:0030016 GO:0030017 GO:0030018 GO:0030049 GO:0030054 GO:0030898 GO:0031449 GO:0032807 GO:0032982 GO:0042803 GO:0046034 GO:0046982 GO:0051103 GO:0051351 GO:0055010 GO:0060048 GO:0070419 GO:0071285 GO:0075713
6	0.07	0.541	4.15	0.04	0.85	3mudA	GO:0000793 GO:0003677 GO:0003779 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005856 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006974 GO:0008022 GO:0010165 GO:0016874 GO:0016925 GO:0030054 GO:0032807 GO:0051103 GO:0051351 GO:0070419 GO:0071285 GO:0075713
7	0.07	0.517	4.39	0.05	0.86	5chxA	GO:0000146 GO:0000166 GO:0000793 GO:0001725 GO:0002026 GO:0002027 GO:0003009 GO:0003677 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005634 GO:0005654 GO:0005737 GO:0005813 GO:0005829 GO:0005859 GO:0005958 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006936 GO:0006941 GO:0006974 GO:0007512 GO:0008022 GO:0010165 GO:0014728 GO:0014883 GO:0016459 GO:0016874 GO:0016887 GO:0016925 GO:0030016 GO:0030017 GO:0030018 GO:0030049 GO:0030054 GO:0030898 GO:0031449 GO:0032807 GO:0032982 GO:0042803 GO:0046034 GO:0046982 GO:0051103 GO:0051351 GO:0055010 GO:0060048 GO:0070419 GO:0071285 GO:0075713
8	0.07	0.528	3.85	0.04	0.78	4gfcA	GO:0005737 GO:0005814 GO:0005856 GO:0007049 GO:0007099 GO:0007275 GO:0008104 GO:0019904 GO:0042802 GO:0051726
9	0.07	0.480	4.00	0.05	0.72	4gfcB	GO:0005737 GO:0005814 GO:0005856 GO:0007049 GO:0007099 GO:0007275 GO:0008104 GO:0019904 GO:0042802 GO:0051726
10	0.07	0.534	3.71	0.04	0.77	5al7A	GO:0005737 GO:0005813 GO:0005814 GO:0005815 GO:0005856 GO:0007049 GO:0007052 GO:0007099 GO:0010457 GO:0051297 GO:0051298
11	0.07	0.477	3.62	0.04	0.69	4gexC	GO:0005737 GO:0005814 GO:0005856 GO:0007049 GO:0007099 GO:0007275 GO:0008104 GO:0019904 GO:0042802 GO:0051726
12	0.06	0.540	3.92	0.05	0.80	3q0xA	GO:0042802
13	0.06	0.431	3.37	0.04	0.59	2y3wC	GO:0000280 GO:0005737 GO:0005813 GO:0005814 GO:0005815 GO:0005856 GO:0007049 GO:0007052 GO:0007099 GO:0007283 GO:0040016 GO:0051298 GO:0098536
14	0.06	0.547	3.94	0.11	0.84	2qm4A	GO:0003677 GO:0005634 GO:0005654 GO:0006281 GO:0006302 GO:0006303 GO:0006310 GO:0006974 GO:0007417 GO:0010212 GO:0030183 GO:0030217 GO:0051351 GO:0070419
15	0.06	0.334	5.51	0.03	0.65	4a7zA	GO:0003824 GO:0008152 GO:0016829 GO:0016836 GO:0016853 GO:0033991 GO:0046872
16	0.06	0.364	4.99	0.02	0.63	3a1jA	GO:0000075 GO:0000076 GO:0000077 GO:0004518 GO:0004527 GO:0005634 GO:0005654 GO:0005737 GO:0006260 GO:0006281 GO:0006974 GO:0008408 GO:0008853 GO:0016787 GO:0017124 GO:0019899 GO:0019901 GO:0030896 GO:0031573 GO:0042826 GO:0071479 GO:0090305 GO:1901796 GO:1902231
17	0.06	0.314	5.54	0.03	0.62	2bduA	GO:0000166 GO:0000287 GO:0005737 GO:0005739 GO:0005783 GO:0008152 GO:0008253 GO:0009117 GO:0016311 GO:0016740 GO:0016787 GO:0016791 GO:0046085 GO:0046872
18	0.06	0.309	5.57	0.09	0.61	3s81B	GO:0006520 GO:0006807 GO:0008152 GO:0009252 GO:0016853 GO:0016855 GO:0036361 GO:0046872 GO:0047661

Consensus prediction of GO terms

Molecular Function	GO:0003676	GO:0042803	GO:0032947	GO:0042623	GO:0032559	GO:0008092	GO:0035639	GO:0003774	GO:0032550
GO-Score	0.41	0.41	0.30	0.30	0.30	0.30	0.30	0.30	0.30
Biological Processes	GO:0006303	GO:0051103	GO:0018205	GO:0010226	GO:0043085	GO:0010212	GO:0019043	GO:0032446	GO:0071248	GO:0051340	GO:0014724	GO:0046128	GO:0014733	GO:0003208	GO:0031444	GO:0033275	GO:0003229	GO:0065008	GO:0008016	GO:0009150	GO:0014862	GO:0009167	GO:0009205	GO:0055008
GO-Score	0.45	0.45	0.41	0.41	0.41	0.41	0.41	0.41	0.41	0.41	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30	0.30
Cellular Component	GO:0005815	GO:0070419	GO:0031981	GO:0070062	GO:0043564	GO:0035861	GO:0097517	GO:0031674	GO:0016460	GO:0042641
GO-Score	0.53	0.45	0.41	0.30	0.30	0.30	0.30	0.30	0.30	0.30

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv2645

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]