I-TASSER results

Input Sequence in FASTA format

>protein (225 residues)
MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFW
FALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMN
VIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAH
ADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFWFALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAHADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS
Prediction	CCCHHHHHHHHHHCCCCCCCCCCEEEEEHCCCCCCHHHHHHHHHHHHCCCEEEEEHCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCCCHHHHHHHHHHHCCCCEEEEEEHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
Conf.Score	998556555666556667788986999978999988999999999968985899754556446765567766666666665455555445543454445556677789999999998995897544589999999999978998799999599999999999858986654566665546899985999789999999999999999978997799999987679
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFWFALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAHADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS
Prediction	744566354445624426715411000001342011210041027307432110001202421454326445244432544442445435423343343133113122410220053413000101133451144026205724011010103350034026726744432043225303663411010103624154005301520675642610540373438
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCHHHHHHHHHHCCCCCCCCCCEEEEEHCCCCCCHHHHHHHHHHHHCCCEEEEEHCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCCCHHHHHHHHHHHCCCCEEEEEEHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFWFALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAHADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS

1qhxA

0.28

0.22

0.78

1.81

MUSTER

--------------------MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLMQSAEGGIEF-------------DADGGVSIGPEFRALEGAWAEGVVAMARAGARIIIDDVFLGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1qhxA

0.26

0.20

0.79

2.02

dPPAS

--------------------MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLKMQSAEGG------------IEFDADGGVSIGPEFRALEGAWAEGVVAMARAGARIIIDVFLGGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1qhxA

0.26

0.20

0.77

2.42

wdPPAS

--------------------MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLSAEGGIEFDADGG---------------VSIGPEFRALEGAWAEGVVAMARAGARIIIDVFLGGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1qhxA

0.28

0.22

0.78

2.32

wMUSTER

---------------------TTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLMQSAEGGIE-------------FDADGGVSIGPEFRALEGAWAEGVVAMARAGARIIIDDVFLGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1xnjB1

0.16

0.13

0.82

2.93

wPPAS

--H---SRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYT-----------LDGDNIRQGLNKNLGFSP------------EDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHESLPFFEVFVDAPLHVCEQRDYKKAGEIKGFTGIDS-EYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP-----------

1qhxA

0.26

0.20

0.77

3.88

dPPAS2

--------------------MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLSAEGGIEFDADGG---------------VSIGPEFRALEGAWAEGVVAMARAGARIIIDVFLGGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1qhxA

0.26

0.20

0.77

2.66

PPAS

--------------------MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLSAEGGIEFDADGG---------------VSIGPEFRALEGAWAEGVVAMARAGARIIIDVFLGGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1qhxA

0.26

0.20

0.79

3.12

Env-PPAS

--------------------MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLKMQ----SAEGGIEF--------DADGGVSIGPEFRALEGAWAEGVVAMARAGARIIIDVFLGGAAAQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHEGVEYDVEVDTTHKESIECAWAIAAHVVP----------------

1xnjB1

0.16

0.13

0.83

1.72

MUSTER

----HVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYT-----------LDGDNIRQGLNKNLGFSP------------EDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHESLPFFEVFVDAPLHVCEQRDVKGLGEIKGFTGIDS-EYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP-----------

1xnjB1

0.16

0.13

0.83

1.77

dPPAS

----HVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYT-----------LDGDNIRQGLNKNLGFSP------------EDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHESLPFFEVFVDAPLHVCEQRDVKGLGEIKGFTGIDS-EYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVP-----------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.43

Estimated TM-score = 0.66±0.13

Estimated RMSD = 6.5±3.9Å

Download Model 2

C-score=-2.37

Download Model 3

C-score=-1.52

Download Model 4

C-score=-1.49

Download Model 5

C-score=-2.89

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1xnjB	0.716	3.03	0.140	0.853
2	1qhxA	0.702	2.38	0.274	0.778
3	3uieA	0.678	2.77	0.162	0.796
4	1i2dA	0.664	3.45	0.141	0.818
5	1m7gC	0.654	2.69	0.143	0.760
6	2gksB	0.653	3.66	0.130	0.822
7	2yvuA	0.637	2.79	0.178	0.751
8	4bzpA	0.624	2.46	0.156	0.711
9	4eunA	0.623	2.61	0.160	0.733
10	5cb6A	0.622	2.60	0.142	0.720

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.65	97	2ax4B	ADP	Rep, Mult	32,35,36,37,38,160,164,191,195,196,199
2	0.03	5	1grqA	CLK	Rep, Mult	31,32,36,37,56,57,88,124,126,128,171,175
3	0.03	7	1qhsA	CLM	Rep, Mult	32,56,57,60,84,88,96,126,128,167,171,175
4	0.02	4	1m7gA	SO4	Rep, Mult	130,133,134,147,183,184
5	0.02	4	1qhxA	MG	Rep, Mult	36,37,57,124
6	0.01	2	1m7g0	III	Rep, Mult	52,72,73,81,105,106,109,110,113,114,116,117
7	0.00	1	2ofwC	MG	Rep, Mult	37,71
8	0.00	1	1m7hA	SO4	Rep, Mult	74,100,125,126
9	0.00	1	1qhsA	CLM	Rep, Mult	195,197,198,201
10	0.00	1	1qhsA	CLM	Rep, Mult	64,66,67,70,99
11	0.00	1	1m7gA	SO4	Rep, Mult	7,8,11

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.249	2ofxA	0.701	2.76	0.151	0.818	2.7.7.4	35,37,57
2	0.200	1ki9B	0.584	3.32	0.145	0.733	2.7.4.3	30,35,37,124
3	0.196	2peyB	0.604	2.14	0.145	0.676	2.7.1.25,2.7.7.4	35,37
4	0.176	1lvgA	0.583	3.70	0.117	0.751	2.7.4.8	32,36,106,124
5	0.171	2p0eA	0.566	3.47	0.160	0.720	2.7.1.22	35,37,54,94,100
6	0.169	1viaA	0.535	3.46	0.133	0.662	2.7.1.71	35,59
7	0.166	1rkbA	0.584	3.26	0.142	0.720	2.7.4.3	35,37,57
8	0.163	3bafA	0.558	3.07	0.143	0.680	2.7.1.71	35
9	0.140	2pt5B	0.543	3.38	0.115	0.671	2.7.1.71	35
10	0.135	1kagA	0.531	3.12	0.086	0.649	2.7.1.71	NA
11	0.134	2ax4C	0.705	2.67	0.145	0.822	2.7.1.25,2.7.7.4	35,37,57,72
12	0.127	2grjG	0.544	3.20	0.112	0.676	2.7.1.24	35
13	0.090	2cdnA	0.593	3.33	0.145	0.751	2.7.4.3	36,164
14	0.082	1ukyA	0.609	3.55	0.107	0.782	2.7.4.-	36,160,167
15	0.074	2pbrB	0.595	3.52	0.129	0.756	2.7.4.9	37,55,124
16	0.074	1z6gA	0.585	3.85	0.076	0.764	2.7.4.8	NA
17	0.073	1z83A	0.607	3.48	0.101	0.773	2.7.4.3	164,167
18	0.073	1qf9A	0.619	3.23	0.091	0.782	2.7.4.14	36,164,167
19	0.070	1gkyA	0.575	3.56	0.145	0.738	2.7.4.8	30,35,124
20	0.069	1zuiA	0.543	3.31	0.113	0.667	2.7.1.71	35
21	0.060	3dkvA	0.614	3.12	0.141	0.756	2.7.4.3	167
22	0.060	1khtB	0.601	3.40	0.089	0.751	2.7.4.3	35,37,52
23	0.060	1m8pA	0.663	3.15	0.122	0.800	2.7.7.4	NA
24	0.060	2qajB	0.613	3.12	0.118	0.756	2.7.4.3	35,53,62,164,166
25	0.060	1m7hC	0.693	2.62	0.164	0.804	2.7.1.25	35
26	0.060	2bwjA	0.591	3.69	0.090	0.782	2.7.4.3	30,35
27	0.060	1nksD	0.614	3.06	0.095	0.747	2.7.4.3	35,124,179
28	0.060	1xjqB	0.718	2.96	0.130	0.849	2.7.1.25,2.7.7.4	NA
29	0.060	1p6xA	0.596	3.86	0.109	0.791	2.7.1.21	167
30	0.060	1dvrA	0.592	3.56	0.124	0.756	2.7.4.3	35,164
31	0.060	2bifA	0.575	4.26	0.129	0.782	3.1.3.46,2.7.1.105	35,37
32	0.060	2yvuA	0.637	2.79	0.178	0.751	2.7.1.25	35,37,57,126
33	0.060	2eu8A	0.616	3.11	0.112	0.756	2.7.4.3	36,57
34	0.060	2dwoA	0.592	4.24	0.095	0.800	2.7.1.105,3.1.3.46	NA
35	0.060	1kofA	0.604	3.14	0.120	0.738	2.7.1.12	35,59
36	0.060	1zinA	0.615	3.11	0.117	0.760	2.7.4.3	36,160,177
37	0.060	2f6rA	0.605	3.43	0.140	0.769	2.7.1.24,2.7.7.3	35,57,160,175,191
38	0.060	1x6vA	0.661	2.40	0.147	0.756	2.7.1.25,2.7.7.4	NA
39	0.060	1bifA	0.578	4.23	0.123	0.787	3.1.3.46,2.7.1.105	37

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.42	0.700	2.39	0.27	0.78	1grqA	GO:0000166 GO:0005524 GO:0016301 GO:0016310 GO:0016740 GO:0046677
1	0.34	0.718	2.96	0.13	0.85	1xjqB	GO:0000103 GO:0000166 GO:0001501 GO:0003824 GO:0004020 GO:0004781 GO:0005524 GO:0005829 GO:0008152 GO:0016301 GO:0016310 GO:0016740 GO:0016779 GO:0050428
2	0.34	0.705	2.68	0.14	0.82	2ax4A	GO:0000103 GO:0000166 GO:0001501 GO:0003824 GO:0004020 GO:0004781 GO:0005524 GO:0005829 GO:0007596 GO:0008152 GO:0016301 GO:0016310 GO:0016740 GO:0016779 GO:0050428 GO:0060348
3	0.33	0.582	2.84	0.15	0.70	1y63A	GO:0000166 GO:0004017 GO:0005524 GO:0005634 GO:0016301 GO:0016310 GO:0016740 GO:0016887 GO:0046872 GO:0046939
4	0.32	0.654	2.69	0.14	0.76	1m7gC	GO:0000103 GO:0000166 GO:0004020 GO:0005524 GO:0005829 GO:0008652 GO:0009086 GO:0016301 GO:0016310 GO:0016740 GO:0019344 GO:0070814 GO:0098617
5	0.32	0.583	3.12	0.18	0.71	3addA	GO:0000166 GO:0005524 GO:0016301 GO:0016310 GO:0016740 GO:0016773 GO:0097056
6	0.31	0.653	3.66	0.13	0.82	2gksB	GO:0000103 GO:0000166 GO:0003824 GO:0004020 GO:0004781 GO:0005524 GO:0008152 GO:0016301 GO:0016310 GO:0016740 GO:0016779 GO:0070814
7	0.30	0.562	3.70	0.17	0.73	1vhlA	GO:0000166 GO:0004140 GO:0005524 GO:0005737 GO:0015937 GO:0016301 GO:0016310 GO:0016740
8	0.28	0.583	3.43	0.16	0.74	3crmA	GO:0000166 GO:0005524 GO:0006400 GO:0008033 GO:0016740 GO:0052381
9	0.23	0.645	2.63	0.15	0.75	1d6jB	GO:0000103 GO:0000166 GO:0004020 GO:0005524 GO:0005829 GO:0008652 GO:0009086 GO:0016301 GO:0016310 GO:0016740 GO:0019344 GO:0070814 GO:0098617
10	0.22	0.671	2.99	0.15	0.80	4fxpB	GO:0000103 GO:0000166 GO:0004020 GO:0005524 GO:0008652 GO:0009507 GO:0009536 GO:0016301 GO:0016310 GO:0016740 GO:0019344 GO:0070814
11	0.19	0.624	2.46	0.16	0.71	4bzpA	GO:0000103 GO:0000166 GO:0003924 GO:0004020 GO:0005524 GO:0005525 GO:0006790 GO:0016301 GO:0016310 GO:0016740 GO:0016779
12	0.18	0.628	2.66	0.14	0.73	5cb8B	GO:0000103 GO:0000166 GO:0004020 GO:0004781 GO:0005524 GO:0016301 GO:0016310 GO:0016740 GO:0070814
13	0.16	0.637	2.79	0.18	0.75	2yvuA	GO:0000103 GO:0000166 GO:0004020 GO:0005524 GO:0016301 GO:0016310 GO:0016740 GO:0070814
14	0.16	0.532	3.68	0.15	0.70	3cm0A	GO:0000166 GO:0004017 GO:0005524 GO:0005737 GO:0006139 GO:0009165 GO:0016301 GO:0016310 GO:0016740 GO:0019205 GO:0044209 GO:0046939
15	0.14	0.542	3.46	0.12	0.67	1viaA	GO:0000166 GO:0000287 GO:0004765 GO:0005524 GO:0005737 GO:0008652 GO:0009073 GO:0009423 GO:0016301 GO:0016310 GO:0016740 GO:0046872
16	0.14	0.540	3.64	0.17	0.70	1t3hC	GO:0000166 GO:0004140 GO:0005524 GO:0005737 GO:0015937 GO:0016301 GO:0016310 GO:0016740
17	0.11	0.663	3.15	0.12	0.80	1m8pA	GO:0000096 GO:0000103 GO:0000166 GO:0003824 GO:0004020 GO:0004781 GO:0005524 GO:0005737 GO:0008152 GO:0008652 GO:0009086 GO:0016310 GO:0016740 GO:0016779 GO:0019344 GO:0070814
18	0.09	0.512	3.53	0.12	0.64	3c8uA	GO:0008865 GO:0016301 GO:0016310 GO:0016740 GO:0046835
19	0.08	0.661	2.40	0.15	0.76	1x6vA	GO:0000103 GO:0000166 GO:0001501 GO:0003824 GO:0004020 GO:0004781 GO:0005524 GO:0005829 GO:0008152 GO:0016301 GO:0016310 GO:0016740 GO:0016779 GO:0050428
20	0.08	0.551	3.55	0.17	0.72	3h0kA	GO:0000166 GO:0005524
21	0.07	0.623	2.61	0.16	0.73	4eunA	GO:0000166 GO:0005524 GO:0005975 GO:0016301 GO:0016310 GO:0016740 GO:0046316
22	0.07	0.577	3.03	0.13	0.70	3vaaA	GO:0000166 GO:0000287 GO:0004765 GO:0005524 GO:0005737 GO:0008652 GO:0009073 GO:0009423 GO:0016301 GO:0016310 GO:0016740 GO:0019632 GO:0046872
23	0.07	0.531	3.12	0.09	0.65	1kagA	GO:0000166 GO:0000287 GO:0004765 GO:0005524 GO:0005737 GO:0005829 GO:0008652 GO:0009073 GO:0009423 GO:0016301 GO:0016310 GO:0016740 GO:0019632 GO:0046872
24	0.07	0.525	3.49	0.15	0.68	2if2C	GO:0000166 GO:0004140 GO:0005524 GO:0005737 GO:0015937 GO:0016301 GO:0016310 GO:0016740
25	0.07	0.542	3.10	0.16	0.66	4cw7A	GO:0000166 GO:0004017 GO:0005524 GO:0016301 GO:0016310 GO:0016740 GO:0046939
26	0.07	0.556	1.97	0.16	0.61	4rfvA	GO:0000103 GO:0000166 GO:0003824 GO:0003924 GO:0004020 GO:0004781 GO:0005524 GO:0005525 GO:0005829 GO:0005886 GO:0006790 GO:0008152 GO:0009336 GO:0010134 GO:0010438 GO:0016301 GO:0016310 GO:0016740 GO:0016779 GO:0034599 GO:0040007 GO:0070814
27	0.07	0.526	4.04	0.12	0.71	1z8fA	GO:0000166 GO:0000287 GO:0004017 GO:0004385 GO:0005524 GO:0005737 GO:0006163 GO:0016301 GO:0016310 GO:0016740 GO:0019002 GO:0019003 GO:0040007 GO:0046037 GO:0046710 GO:0046939
28	0.07	0.521	4.46	0.11	0.72	2p5tD	GO:0000166 GO:0005524 GO:0009405 GO:0016301 GO:0016310 GO:0016740
29	0.07	0.468	4.06	0.09	0.62	3dmdB	GO:0000166 GO:0003924 GO:0005525 GO:0005737 GO:0005886 GO:0006612 GO:0006614 GO:0016020 GO:0031226
30	0.07	0.461	3.81	0.12	0.60	5l3rC	GO:0000166 GO:0003723 GO:0003924 GO:0005525 GO:0005786 GO:0006614 GO:0008312 GO:0009507 GO:0009536 GO:0009570 GO:0030529 GO:0048500 GO:0080085

Consensus prediction of GO terms

Molecular Function	GO:0005524	GO:0004020	GO:0004781	GO:0016887	GO:0046872	GO:0004017	GO:0098617
GO-Score	0.89	0.71	0.57	0.33	0.33	0.33	0.32
Biological Processes	GO:0000103	GO:0050428	GO:0046677	GO:0007596	GO:0060348	GO:0046939	GO:0019344	GO:0070814	GO:0009086
GO-Score	0.71	0.57	0.42	0.34	0.34	0.33	0.32	0.32	0.32
Cellular Component	GO:0005829	GO:0005634
GO-Score	0.71	0.33

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv2636

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]