Threading Zmax Znorm MUSTER 6.14 1.06 dPPAS 10.44 1.12 wdPPAS 17.37 1.87 wMUSTER 7.30 1.26 wPPAS 11.20 1.60 dPPAS2 34.03 3.24 PPAS 7.80 1.11 Env-PPAS 14.00 1.75 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11538) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 0.20 0.74+-0.11 4.5+-3.0 9912 0.754 model2 -3.20 566 0.025 model3 -2.88 496 0.034 model4 -4.50 189 0.007 model5 -3.90 118 0.012 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).