I-TASSER results

Input Sequence in FASTA format

>protein (161 residues)
MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAA
GKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPV
HITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAAGKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPVHITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI
Prediction	CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCC
Conf.Score	97999999999999999999998999999999999999999999999999998776665897589999999999999999996999998999999999999999999999999999999699999999999999999998667777665677864555579
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 \| \| \| \| \| \| \| \| MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAAGKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPVHITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI
Prediction	64034003610640361054047167447404500530261043004002320102047466434533531630450054057154527503510540262045015511651144047352477205510541462166247453561545352522656
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160

                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCC
MNAYDVLKRHHTVLKGLGRKVGEAPVNSEERHVLFDEMLIELDIHFRIEDDLYYPALSAAGKPITGTHAEHRQVVDQLATLLRTPQRAPGYEEEWNVFRTVLEAHADVEERDMIPAPTPVHITDAELEELGDKMAARIEQLRGSPLYTLRTKGKADLLKAI

3caxA1

0.09

0.99

1.05

MUSTER

LPPLKTLYQENKEIMKDAEMLNLYTKDLGVLEEIVSSLRMVGFTHYNREEMLIFPYIERRGVIATVLWTKHDEIRAMIKQLAELEEFVEKFKAKAGEVAFALSDMVFRENNIFYPTLKAL-LSEGEWKAIKMQEDEYKVKPPEDPGEDVKPLHPWEINPEL

3caxA1

0.09

0.99

1.12

dPPAS

YQENKEIMKDAEMLNLYAKTLATTKDELGVLEEIVSSLRMVGFTHYNREEMLIFPYIERRGVIATVLWTKHDEIRAMIKQLAELEEMPEKFKAKAGEVAFALSDMVFRENNIFYPTLKAL-LSEGEWKAIKMQEDEKVKPPEWDPGEDVKPLHPWEINPEL

2p0nA

0.17

0.14

0.81

1.93

wdPPAS

IE----LYACHGKVRRFCGQVALSQIVLQTIRQIAQYFNVAAPLHHEDEEENFFPLLLQYAPSVDELLRQHIGLHDNWAAVSAEDNAYVPDEEAFKRFVAGYDVHLAIEEPLFDGNT----IPKEKLTEIGEIAARRRK----------------------

3caxA1

0.09

0.97

1.22

wMUSTER

--PLKTLYQENKEIMKDAEMLNLYTKDLGVLEEIVSSLRMVGFTHYNREEMLIFPYIERRGVIATVLWTKHDEIRAMIKQLAELEMPWEKFKAKAGEVAFALSDMVFRENNIFYPTLKAL-LSEGEWKAIKMQEDEI--KPPEDPGEDVKPLHPWEINPEL

2p0nA

0.17

0.14

0.82

1.49

wPPAS

IE----LYACHGKVRRFCGQVALSQIVLQTIRQIAQYFNVAAPLHHEDEEENFFPLLLQYAPSVDELLRQHIGLHDNWAAVSAEDNAYVPDEEAFKRFVAGYDVHLAIEEPLFDGNTF---IPKEKLTEIGEIAARRRK----------------------

3caxA1

0.09

0.98

3.24

dPPAS2

--PLKTLYQENKEIMKDAEMLNLYTKDLGVLEEIVSSLRMVGFTHYNREEMLIFPYIERRGVIATVLWTKHDEIRAMIKQLAELEEMPEKFKAKAGEVAFALSDMVFRENNIFYPTLKAL-LSEGEWKAIKMQEDEKVKPPEWDPGEDVKPLHPWEINPEL

3caxA1

0.09

0.98

1.11

PPAS

GHPLKTLYQENKEIMKDAEMLNLYAKTLGVLEEIVSSLRMVGFTHYNREEMLIFPYIERRGVIATVLWTKHDEIRAMIKQLAELEEMPEKFKAKAGEVAFALSDMVFRENNIFYPTLKAL-LSEGEWKAIKMQEDE--KPPEWDPGEDVKPLHPWEINPEL

3caxA1

0.09

0.99

1.75

Env-PPAS

GHPLKTLYQENKEIMKDAEMLNLYAKTLGVLEEIVSSLRMVGFTHYNREEMLIFPYIERRGVIATVLWTKHDEIRAMIKQLAELEEFVEKFKAKAGEVAFALSDMVFRENNIFYPTLKAL-LSEGEWKAIKMQEDEYKVKPPEDPGEDVKPLHPWEINPEL

5cwjA

0.11

0.10

0.94

0.97

MUSTER

-----DSEEEQERIRRILKEARK-SGTEESLRQAIEDVAQLAKK-SEVLEEAIRVILRIA--KESGSEEALRQAIRAVAEIAKEAQDSEVLEEAIRVILRIAKESGSEEALRQAIRAVAEIAKEAQDPRVLEEAIRVIRQIAEESGSEEARRQAERAEEEI

5cwjA

0.06

0.97

1.12

dPPAS

-----DSEEEQERIRRILKEARKSGTEESLRQAIEDVAQLAKKSEVLEEAIRVILRIAKESGSEEALRQAIRAVAEIAKEAQDSEVLEEAIRVILRIAKESGSEEALRQAIRAVAEIAKEAQDPRVLEEAIRVIRQIAEESGSEEARRQAERAEEEIRRRA

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.20

Estimated TM-score = 0.74±0.11

Estimated RMSD = 4.5±3.0Å

Download Model 2

C-score=-3.20

Download Model 3

C-score=-2.88

Download Model 4

C-score=-4.50

Download Model 5

C-score=-3.90

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3caxA	0.929	1.47	0.087	0.994
2	3n8uA	0.709	2.87	0.082	0.870
3	3v5xA	0.649	2.38	0.071	0.783
4	4ecgA	0.646	4.11	0.068	0.913
5	5doqA	0.644	3.35	0.086	0.857
6	4iggA4	0.643	3.31	0.029	0.832
7	2p0nA	0.641	3.00	0.097	0.826
8	3pf0A	0.637	3.68	0.042	0.870
9	5doqB	0.632	3.38	0.065	0.863
10	1oczC2	0.631	2.55	0.041	0.752

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.41	17	2avkA	FEA	Rep, Mult	11,14,45,46,49,67,71,101,102,105,106
2	0.06	3	2qjyG	HEM	Rep, Mult	18,19,22,23,25,26,31,34,35,38,77,78,81,82,84,85,95,96,99
3	0.06	3	4xpxA	FE2	Rep, Mult	11,45,49
4	0.02	1	1rke1	III	Rep, Mult	28,29,32,70,73,76,77,80,81,93,94,97,100,101,104,108
5	0.02	1	2ibfA	III	Rep, Mult	28,29,31,32,35,36,39,42,43,75
6	0.02	1	2yiuD	HEM	Rep, Mult	14,15,18,19,22,38,39,42,45,74,78,79,81,82,98,99,102
7	0.02	1	3rf3A	III	Rep, Mult	47,49,69

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.177	1q0mD	0.516	2.78	0.058	0.646	1.15.1.1	43,75,104,107
2	0.138	1tqgA	0.488	2.49	0.052	0.603	2.7.13.3	37
3	0.108	3g4xA	0.510	2.85	0.029	0.646	1.15.1.1	107
4	0.096	2kk1A	0.486	2.73	0.062	0.590	2.7.10.2	42
5	0.091	3eziA	0.481	3.22	0.125	0.646	2.7.13.3	16
6	0.060	3czoB	0.551	4.00	0.038	0.795	4.3.1.3	NA
7	0.060	2e76A	0.565	2.57	0.053	0.702	1.10.99.1	38,47
8	0.060	1occA	0.550	4.61	0.071	0.863	1.9.3.1	71
9	0.060	2o6yA	0.542	3.85	0.051	0.733	4.3.1.-	NA
10	0.060	3gm1B	0.606	2.79	0.137	0.758	2.7.10.2	66,112
11	0.060	1k04A	0.478	3.11	0.122	0.621	2.7.10.2	106
12	0.060	1qleA	0.563	3.73	0.052	0.776	1.9.3.1	71
13	0.060	1yfmA	0.554	3.81	0.054	0.807	4.2.1.2	NA
14	0.060	1k62B	0.559	3.83	0.044	0.807	4.3.2.1	NA
15	0.060	2wpnB	0.541	4.21	0.056	0.795	1.12.7.2	NA
16	0.060	3cxhN	0.604	4.22	0.044	0.888	1.10.2.2	18,81
17	0.060	1yrqI	0.545	4.07	0.038	0.764	1.12.2.1	NA
18	0.060	1yqwR	0.546	4.18	0.038	0.776	1.12.2.1	NA
19	0.060	1yfeA	0.543	4.27	0.046	0.814	4.2.1.2	NA
20	0.060	1dofA	0.545	4.11	0.092	0.789	4.3.2.2	103
21	0.060	2pnrF	0.519	4.41	0.082	0.764	2.7.11.2	52,130,137
22	0.060	3no9A	0.573	3.72	0.052	0.814	4.2.1.2	NA
23	0.060	3e04D	0.570	3.70	0.046	0.807	4.2.1.2	97,104
24	0.060	2a06C	0.601	4.13	0.031	0.876	1.10.2.2	81

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.17	0.644	2.82	0.06	0.83	3u9jA	GO:0000151 GO:0004842 GO:0005506 GO:0005737 GO:0016567 GO:0019005 GO:0031146 GO:0046872 GO:0048471 GO:0055072 GO:1903364
1	0.14	0.568	3.39	0.05	0.77	4k1oA	GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
2	0.13	0.575	3.16	0.06	0.74	4p9tA	GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
3	0.13	0.614	3.15	0.05	0.80	4iggB	GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034332 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0051015 GO:0051149 GO:0051291 GO:0071681 GO:0090136 GO:0098641 GO:2000146 GO:2001045 GO:2001240 GO:2001241
4	0.09	0.644	3.35	0.09	0.86	5doqA	GO:0016020 GO:0016021
5	0.07	0.666	3.91	0.07	0.92	4ecgA	GO:0046872
6	0.07	0.574	3.76	0.04	0.80	3dyjA	GO:0001726 GO:0003779 GO:0005178 GO:0005200 GO:0005737 GO:0005815 GO:0005856 GO:0005886 GO:0005925 GO:0007016 GO:0007044 GO:0007155 GO:0009986 GO:0016020 GO:0017166 GO:0030054 GO:0030274 GO:0030866 GO:0032403 GO:0032587 GO:0042995 GO:0051015 GO:0070062 GO:0070527
7	0.07	0.617	3.74	0.05	0.84	1st6A	GO:0001725 GO:0002009 GO:0002162 GO:0003779 GO:0005198 GO:0005623 GO:0005737 GO:0005743 GO:0005856 GO:0005886 GO:0005903 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005916 GO:0005925 GO:0005927 GO:0007155 GO:0008013 GO:0015629 GO:0016020 GO:0017166 GO:0030018 GO:0030032 GO:0030054 GO:0030334 GO:0030486 GO:0031594 GO:0031625 GO:0034333 GO:0034394 GO:0042383 GO:0042803 GO:0043034 GO:0043234 GO:0043297 GO:0045121 GO:0045294 GO:0045296 GO:0048675 GO:0051015 GO:0051371 GO:0051393 GO:0070062 GO:0070527 GO:0090136 GO:0090636 GO:0090637 GO:0097110 GO:0098723 GO:1903561 GO:1990357
8	0.07	0.553	2.63	0.12	0.70	1dowA	GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
9	0.07	0.574	2.50	0.07	0.71	4k1nA	GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
10	0.07	0.480	3.22	0.04	0.62	4onsC	GO:0005198 GO:0005634 GO:0005737 GO:0005856 GO:0005886 GO:0005912 GO:0005913 GO:0007155 GO:0007275 GO:0007409 GO:0015629 GO:0016020 GO:0016323 GO:0016337 GO:0021942 GO:0030027 GO:0030054 GO:0030154 GO:0030424 GO:0042995 GO:0045296 GO:0048813 GO:0048854 GO:0051015 GO:0051823 GO:0060134 GO:0097481
11	0.07	0.333	5.38	0.02	0.58	2q5lA	GO:0000287 GO:0003824 GO:0009851 GO:0016829 GO:0016831 GO:0030976 GO:0046872 GO:0047434
12	0.06	0.405	4.93	0.06	0.67	3svtB	GO:0016491 GO:0055114
13	0.06	0.370	5.23	0.04	0.64	3tqeA	GO:0003824 GO:0004314 GO:0008152 GO:0016740 GO:0016746
14	0.06	0.374	4.89	0.04	0.61	1cydA	GO:0004090 GO:0005739 GO:0005759 GO:0006116 GO:0016491 GO:0043621 GO:0051262 GO:0055114
15	0.06	0.368	5.19	0.04	0.62	2aj4A	GO:0000166 GO:0000411 GO:0004335 GO:0005524 GO:0005737 GO:0005975 GO:0006012 GO:0008152 GO:0016301 GO:0016310 GO:0016740 GO:0016773 GO:0033499 GO:0046835
16	0.06	0.366	4.75	0.05	0.60	4wy9A	GO:0004871 GO:0007165 GO:0016020 GO:0016021
17	0.06	0.378	5.85	0.08	0.73	1kaeA	GO:0000105 GO:0004399 GO:0005829 GO:0008152 GO:0008270 GO:0008652 GO:0016491 GO:0030145 GO:0046872 GO:0051287 GO:0055114
18	0.06	0.278	3.72	0.05	0.39	5boxA	GO:0003677 GO:0006351 GO:0006355

Consensus prediction of GO terms

Molecular Function	GO:0051015	GO:0005198	GO:0045296	GO:0019787	GO:0046914
GO-Score	0.35	0.35	0.35	0.34	0.34
Biological Processes	GO:0009887	GO:0016358	GO:0021932	GO:0048667	GO:0001964	GO:0098602	GO:0048812	GO:0050807	GO:0098609	GO:0061564	GO:0032102	GO:0055076	GO:0032446	GO:0031331	GO:1903362	GO:0032270	GO:0045732	GO:0043161
GO-Score	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.34	0.34	0.34	0.34	0.34	0.34	0.34
Cellular Component	GO:0099572	GO:0043231	GO:0098590	GO:0043005	GO:0060076	GO:0005913	GO:0030027	GO:0015629	GO:0044444	GO:0031461
GO-Score	0.50	0.50	0.50	0.50	0.50	0.35	0.35	0.35	0.34	0.34

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv2633c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]