Threading Zmax Znorm MUSTER 5.50 0.95 dPPAS 9.51 1.02 wdPPAS 12.12 1.30 wMUSTER 6.36 1.10 wPPAS 10.72 1.53 dPPAS2 18.22 1.73 PPAS 8.09 1.16 Env-PPAS 12.12 1.51 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=19554) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.70 0.40+-0.14 11.8+-4.5 5493 0.052 model2 -4.08 1405 0.013 model3 -4.18 1115 0.012 model4 -4.61 691 0.008 model5 -3.65 1817 0.020 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).