Threading Zmax Znorm MUSTER 4.25 0.73 dPPAS 7.47 0.80 wdPPAS 6.33 0.68 wMUSTER 4.74 0.82 wPPAS 5.40 0.77 dPPAS2 18.21 1.73 PPAS 5.22 0.75 Env-PPAS 5.82 0.73 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11034) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.37 0.44+-0.14 10.2+-4.6 6562 0.106 model2 -2.83 3997 0.068 model3 -3.51 1649 0.034 model4 -5.00 322 0.007 model5 -2.70 4320 0.077 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).