Threading Zmax Znorm MUSTER 18.59 3.21 dPPAS 35.37 3.80 wdPPAS 46.45 4.99 wMUSTER 26.72 4.61 wPPAS 49.69 7.10 dPPAS2 76.89 7.32 PPAS 44.59 6.37 Env-PPAS 8.97 1.12 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=4518) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.00 0.59+-0.14 9.8+-4.6 794 0.076 model2 -0.45 753 0.132 model3 -1.47 753 0.048 model4 -2.49 408 0.017 model5 -2.01 183 0.028 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).