Threading Zmax Znorm MUSTER 5.56 0.96 dPPAS 7.06 0.76 wdPPAS 6.29 0.68 wMUSTER 5.31 0.92 wPPAS 7.11 1.02 dPPAS2 12.07 1.15 PPAS 8.00 1.14 Env-PPAS 5.61 0.70 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=19554) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.81 0.39+-0.13 13.3+-4.1 3620 0.066 model2 -3.32 1474 0.039 model3 -4.08 1287 0.018 model4 -3.57 804 0.031 model5 -5.00 344 0.006 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).