Threading Zmax Znorm MUSTER 6.60 1.14 dPPAS 23.75 2.55 wdPPAS 23.53 2.53 wMUSTER 6.04 1.04 wPPAS 8.62 1.23 dPPAS2 76.76 7.31 PPAS 9.65 1.38 Env-PPAS 33.05 4.13 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=279) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 0.05 0.72+-0.11 9.1+-4.6 255 0.396 model2 -0.48 134 0.232 model3 -2.20 23 0.042 model4 -0.60 91 0.205 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).