Threading Zmax Znorm MUSTER 7.12 1.23 dPPAS 16.02 1.72 wdPPAS 24.73 2.66 wMUSTER 8.89 1.53 wPPAS 20.43 2.92 dPPAS2 41.03 3.91 PPAS 17.24 2.46 Env-PPAS 36.92 4.62 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=6777) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.16 0.27+-0.08 18.5+-2.2 332 0.006 model2 -4.03 222 0.007 model3 -4.32 199 0.005 model4 -3.96 194 0.007 model5 -4.11 184 0.006 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).