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I-TASSER results for job id Rv2560

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)
 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)
  Ligand binding sites

Rank C-score Cluster
size		 PDB
Hit		 Lig
Name		 Download
Complex		 Ligand Binding Site Residues
10.06 3 2axtK CLA Rep, Mult 288,289,292
20.06 3 2y01A Y01 Rep, Mult 105,113,120,154,157,197
30.04 2 2xqtD CVM Rep, Mult 260,263,267
40.04 2 1l84A BNZ Rep, Mult 157,160,199,206,219,223
50.02 1 2a07G NUC Rep, Mult 297,298
60.02 1 2xquB CVM Rep, Mult 267,271
70.02 1 3pyrI MG Rep, Mult 266,269
80.02 1 2wse2 CLA Rep, Mult 280,281
90.02 1 4ntjA CLR Rep, Mult 171,230,233,234,237
100.02 1 4k5yC 1Q5 Rep, Mult 122,163,166,170,228,231,232,274,278,285
110.02 1 1smyF MG Rep, Mult 299,303
120.02 1 3sb5A MG Rep, Mult 161,164,196
130.02 1 2dysC DCW Rep, Mult 85,88,89,92,284,287
140.02 1 3v2wA ML5 Rep, Mult 132,136,151,152,155,156,159,220,285,292,325
150.02 1 2i37A UUU Rep, Mult 207,215,216,219,220,221
160.02 1 4jkvA 1KS Rep, Mult 73,82,129,216,295,298,299,322
170.02 1 3pdsA CLR Rep, Mult 109,114,117,121,193,197
180.02 1 4ww3B RET Rep, Mult 129,151,152,156,159,160,212,221,224,285,289
190.02 1 4n4wA SNT Rep, Mult 82,122,129,159,160,163,224,281,284,288
200.02 1 1c61A KR Rep, Mult 97,100,101,104,115,118,119

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit		TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.0602o6yA0.4116.070.0810.6374.3.1.-NA
20.0603no9A0.3935.820.0640.6094.2.1.2NA
30.0601dcnB0.3705.480.0600.5574.3.2.1NA
40.0601jtnA0.2155.620.0310.3323.2.1.17179
50.0601w07B0.3945.290.0400.5541.3.3.6103
60.0603d4sA0.5483.950.0530.6863.2.1.17113,175,235,277
70.0601qleA0.4634.750.0440.6151.9.3.1NA
80.0601i0aA0.3815.760.0740.5854.3.2.1NA
90.0602occN0.4674.700.0480.6191.9.3.1NA
100.0602ohyB0.4186.080.0460.6495.4.3.6NA
110.0602nyfA0.4135.260.0470.5974.3.1.5NA
120.0602qb0B0.2706.730.0510.4683.2.1.17NA
130.0603bhgA0.3935.180.0670.5664.3.2.2NA
140.0601k7wD0.3815.740.0630.5884.3.2.1NA
150.0602fonB0.3945.380.0470.5571.3.3.6NA
160.0602pfmA0.3865.590.0330.5884.3.2.2NA
170.0601w27A0.4185.970.0370.6524.3.1.24NA
180.0601yfeA0.3916.140.0720.6154.2.1.2NA
190.0603gtdA0.3936.110.0600.6124.2.1.2256

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.260.7843.800.090.964n4wA GO:0000122 GO:0001503 GO:0001570 GO:0001649 GO:0001701 GO:0001708 GO:0001755 GO:0001947 GO:0002052 GO:0002053 GO:0003007 GO:0003140 GO:0003323 GO:0004871 GO:0004888 GO:0004930 GO:0005113 GO:0005506 GO:0005737 GO:0005794 GO:0005886 GO:0005901 GO:0005929 GO:0007165 GO:0007166 GO:0007186 GO:0007224 GO:0007228 GO:0007275 GO:0007368 GO:0007371 GO:0007389 GO:0007417 GO:0007494 GO:0008144 GO:0008284 GO:0009055 GO:0009952 GO:0009953 GO:0010468 GO:0010628 GO:0010629 GO:0016020 GO:0016021 GO:0017147 GO:0020037 GO:0021542 GO:0021696 GO:0021794 GO:0021904 GO:0021910 GO:0021938 GO:0021953 GO:0021987 GO:0022900 GO:0030666 GO:0030857 GO:0031069 GO:0034504 GO:0035264 GO:0035567 GO:0040018 GO:0042307 GO:0042475 GO:0042597 GO:0042813 GO:0042995 GO:0043066 GO:0043231 GO:0043392 GO:0045880 GO:0045892 GO:0045893 GO:0045944 GO:0046622 GO:0046872 GO:0048143 GO:0048468 GO:0048565 GO:0048568 GO:0048589 GO:0048741 GO:0048853 GO:0048873 GO:0050679 GO:0050821 GO:0051451 GO:0051799 GO:0060070 GO:0060170 GO:0060248 GO:0060413 GO:0060644 GO:0060684 GO:0061053 GO:0061113 GO:0070062 GO:0070986 GO:0071397 GO:0072001 GO:0072285 GO:0072372 GO:0090190 GO:0097542 GO:2000036 GO:2000826
10.180.5893.980.060.744zj8A GO:0004373 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007268 GO:0007631 GO:0008188 GO:0016020 GO:0016021 GO:0016499 GO:0017046 GO:0032870 GO:0042277 GO:0045187 GO:0051480 GO:1901652
20.160.6034.070.090.763v2yA GO:0001525 GO:0001664 GO:0001955 GO:0003245 GO:0003376 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005768 GO:0005829 GO:0005886 GO:0006935 GO:0007155 GO:0007165 GO:0007186 GO:0007193 GO:0007420 GO:0008152 GO:0008284 GO:0009253 GO:0009897 GO:0016020 GO:0016021 GO:0016477 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019226 GO:0019835 GO:0030032 GO:0030155 GO:0030182 GO:0030335 GO:0030430 GO:0030500 GO:0031226 GO:0031532 GO:0038036 GO:0042742 GO:0043547 GO:0045121 GO:0045124 GO:0045446 GO:0045944 GO:0046625 GO:0048661 GO:0050927 GO:0051482 GO:0051497 GO:0061384 GO:0072678
30.150.5663.840.070.715dhhB GO:0001626 GO:0001934 GO:0004871 GO:0004930 GO:0004985 GO:0005506 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007193 GO:0007204 GO:0007218 GO:0007268 GO:0007600 GO:0007610 GO:0008022 GO:0009055 GO:0016020 GO:0016021 GO:0016023 GO:0019233 GO:0020037 GO:0022900 GO:0030817 GO:0030818 GO:0031410 GO:0032355 GO:0035810 GO:0038003 GO:0042597 GO:0042755 GO:0042923 GO:0043005 GO:0044849 GO:0045776 GO:0046872 GO:0051930 GO:0060454 GO:1901386 GO:1904058 GO:1904059
40.110.5454.010.070.694ej4A GO:0000060 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0004985 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007191 GO:0007193 GO:0007200 GO:0007218 GO:0007268 GO:0008152 GO:0008344 GO:0009253 GO:0010629 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019233 GO:0019835 GO:0030430 GO:0031226 GO:0031982 GO:0032460 GO:0032590 GO:0033138 GO:0038003 GO:0038046 GO:0042742 GO:0042755 GO:0042923 GO:0043005 GO:0043679 GO:0045121 GO:0045211 GO:0051881 GO:0051924 GO:0051930 GO:0071363 GO:0071456 GO:0097237
50.070.6343.740.040.782ziyA GO:0004871 GO:0004930 GO:0007165 GO:0007186 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0016021 GO:0018298 GO:0050896
60.070.5993.450.060.724bwbA GO:0001659 GO:0003085 GO:0003254 GO:0004871 GO:0004930 GO:0005737 GO:0005739 GO:0005783 GO:0005794 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007612 GO:0008344 GO:0009898 GO:0009986 GO:0014049 GO:0014054 GO:0016020 GO:0016021 GO:0016492 GO:0030424 GO:0030425 GO:0032280 GO:0033993 GO:0042803 GO:0043025 GO:0043065 GO:0043066 GO:0043195 GO:0043197 GO:0043198 GO:0043204 GO:0043576 GO:0043679 GO:0044309 GO:0045121 GO:0045202 GO:0046982 GO:0047485 GO:0050965 GO:0051280 GO:0051281 GO:0051930 GO:0060732 GO:0070779 GO:0071545 GO:0090238 GO:0097151 GO:0098900 GO:1990123 GO:2001259
70.070.5863.720.060.724xesA GO:0001659 GO:0003085 GO:0003254 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005737 GO:0005739 GO:0005783 GO:0005794 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007612 GO:0008152 GO:0008344 GO:0009253 GO:0009898 GO:0009986 GO:0014049 GO:0014054 GO:0016020 GO:0016021 GO:0016492 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030424 GO:0030425 GO:0030430 GO:0032280 GO:0033993 GO:0042742 GO:0042803 GO:0043025 GO:0043065 GO:0043066 GO:0043195 GO:0043197 GO:0043198 GO:0043204 GO:0043576 GO:0043679 GO:0044309 GO:0045121 GO:0045202 GO:0046982 GO:0047485 GO:0050965 GO:0051280 GO:0051281 GO:0051930 GO:0060732 GO:0070779 GO:0071545 GO:0090238 GO:0097151 GO:0098900 GO:1990123 GO:2001259
80.070.5944.000.080.744z34A GO:0000187 GO:0001965 GO:0004871 GO:0004930 GO:0005506 GO:0005543 GO:0005737 GO:0005768 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007193 GO:0007202 GO:0007204 GO:0007420 GO:0008289 GO:0008360 GO:0009055 GO:0009986 GO:0010942 GO:0010977 GO:0014003 GO:0016020 GO:0016021 GO:0020037 GO:0021549 GO:0021554 GO:0022008 GO:0022038 GO:0022900 GO:0030139 GO:0030165 GO:0030818 GO:0032060 GO:0035025 GO:0035727 GO:0042552 GO:0042597 GO:0043005 GO:0043025 GO:0043065 GO:0043123 GO:0043197 GO:0043198 GO:0043410 GO:0046872 GO:0051482 GO:0051496 GO:0055114 GO:0060326 GO:0060999 GO:0070915 GO:0071453 GO:0071673 GO:1904566
90.070.5774.130.090.742g87A GO:0000139 GO:0001750 GO:0001917 GO:0004871 GO:0004930 GO:0005085 GO:0005794 GO:0005886 GO:0005887 GO:0005911 GO:0006468 GO:0007165 GO:0007186 GO:0007601 GO:0007602 GO:0007603 GO:0008020 GO:0009416 GO:0009583 GO:0009881 GO:0016020 GO:0016021 GO:0016038 GO:0016056 GO:0018298 GO:0022400 GO:0042622 GO:0043547 GO:0045494 GO:0046872 GO:0050896 GO:0050953 GO:0060041 GO:0060342 GO:0071482 GO:0097381
100.070.5983.910.080.742ks9A GO:0002118 GO:0002526 GO:0002687 GO:0003051 GO:0004871 GO:0004930 GO:0004995 GO:0005737 GO:0005829 GO:0005886 GO:0005887 GO:0006954 GO:0007165 GO:0007166 GO:0007186 GO:0007200 GO:0007204 GO:0007217 GO:0007268 GO:0007611 GO:0007616 GO:0008217 GO:0008306 GO:0009408 GO:0009582 GO:0009725 GO:0009986 GO:0010193 GO:0010634 GO:0010996 GO:0014070 GO:0014910 GO:0016020 GO:0016021 GO:0016496 GO:0019233 GO:0030425 GO:0032224 GO:0032230 GO:0032355 GO:0032570 GO:0035094 GO:0035106 GO:0035815 GO:0042713 GO:0042755 GO:0043117 GO:0043278 GO:0044297 GO:0045471 GO:0045760 GO:0045777 GO:0045778 GO:0045907 GO:0045987 GO:0046878 GO:0046887 GO:0048265 GO:0048266 GO:0048660 GO:0050671 GO:0050679 GO:0051496 GO:0051602 GO:0060083 GO:0070472 GO:0070474 GO:0071944
110.070.5894.270.070.754yayA GO:0001558 GO:0001596 GO:0001822 GO:0002018 GO:0002034 GO:0003081 GO:0004871 GO:0004930 GO:0004945 GO:0005506 GO:0005622 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007200 GO:0007204 GO:0007266 GO:0009055 GO:0010744 GO:0010873 GO:0016020 GO:0016021 GO:0019229 GO:0019722 GO:0020037 GO:0022900 GO:0031711 GO:0032270 GO:0032430 GO:0033864 GO:0034374 GO:0035813 GO:0038166 GO:0042127 GO:0042312 GO:0042597 GO:0046872 GO:0046982 GO:0050727 GO:0050729 GO:0051482 GO:0055114 GO:0060326 GO:0086097 GO:2000379
120.070.5823.860.040.733oduA GO:0000187 GO:0001618 GO:0001666 GO:0001764 GO:0002064 GO:0002407 GO:0003779 GO:0004871 GO:0004930 GO:0004950 GO:0005737 GO:0005764 GO:0005768 GO:0005769 GO:0005770 GO:0005886 GO:0006915 GO:0006935 GO:0006954 GO:0007165 GO:0007186 GO:0007204 GO:0008038 GO:0008144 GO:0009615 GO:0009986 GO:0015026 GO:0016020 GO:0016021 GO:0016023 GO:0016032 GO:0016477 GO:0016494 GO:0019064 GO:0019722 GO:0019955 GO:0022029 GO:0030054 GO:0030260 GO:0030334 GO:0031252 GO:0031410 GO:0031625 GO:0032027 GO:0043067 GO:0043130 GO:0043217 GO:0048714 GO:0050920 GO:0051924 GO:0060048 GO:0070062 GO:0070098 GO:0071345
130.070.5784.200.050.744grvA GO:0001659 GO:0003085 GO:0003254 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005737 GO:0005739 GO:0005783 GO:0005794 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007218 GO:0007612 GO:0008152 GO:0008344 GO:0009253 GO:0009898 GO:0009986 GO:0014049 GO:0014054 GO:0016020 GO:0016021 GO:0016492 GO:0016787 GO:0016798 GO:0016998 GO:0019076 GO:0019835 GO:0030424 GO:0030425 GO:0030430 GO:0032280 GO:0033993 GO:0042742 GO:0042803 GO:0043025 GO:0043065 GO:0043066 GO:0043195 GO:0043197 GO:0043198 GO:0043204 GO:0043576 GO:0043679 GO:0044309 GO:0045121 GO:0045202 GO:0046982 GO:0047485 GO:0050965 GO:0051280 GO:0051281 GO:0051930 GO:0060732 GO:0070779 GO:0071545 GO:0090238 GO:0097151 GO:0098900 GO:1990123 GO:2001259
140.070.5683.940.060.714iarA GO:0002031 GO:0004871 GO:0004930 GO:0004993 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007187 GO:0007198 GO:0007205 GO:0007268 GO:0007610 GO:0007631 GO:0008144 GO:0009055 GO:0014059 GO:0014063 GO:0016020 GO:0016021 GO:0020037 GO:0022900 GO:0030818 GO:0032229 GO:0035690 GO:0042220 GO:0042310 GO:0042493 GO:0042597 GO:0042756 GO:0045471 GO:0046849 GO:0046872 GO:0050795 GO:0051378 GO:0051385 GO:0051967 GO:0055114 GO:0071312 GO:0071502
150.070.5693.740.090.705c1mA GO:0001965 GO:0002438 GO:0004871 GO:0004930 GO:0004979 GO:0004985 GO:0005245 GO:0005737 GO:0005829 GO:0005886 GO:0005887 GO:0005925 GO:0007165 GO:0007186 GO:0007191 GO:0007193 GO:0007194 GO:0007200 GO:0007204 GO:0007218 GO:0007268 GO:0007626 GO:0008022 GO:0009314 GO:0016020 GO:0016021 GO:0019233 GO:0019904 GO:0030425 GO:0030818 GO:0031005 GO:0031635 GO:0031681 GO:0032094 GO:0032100 GO:0032496 GO:0032590 GO:0032839 GO:0033554 GO:0038003 GO:0038047 GO:0042060 GO:0042220 GO:0042383 GO:0042755 GO:0042923 GO:0043005 GO:0043204 GO:0043278 GO:0043950 GO:0043951 GO:0044849 GO:0045019 GO:0045121 GO:0045429 GO:0045471 GO:0048149 GO:0050769 GO:0051481 GO:0051930 GO:0060079 GO:0061358 GO:0070374 GO:0070588 GO:0070848 GO:0071315 GO:0098794 GO:2000310
160.070.5764.430.070.745dgyA GO:0000139 GO:0001523 GO:0001750 GO:0001917 GO:0002046 GO:0003796 GO:0003824 GO:0004871 GO:0004930 GO:0005794 GO:0005886 GO:0005887 GO:0005911 GO:0006468 GO:0007165 GO:0007186 GO:0007601 GO:0007602 GO:0007603 GO:0008020 GO:0008152 GO:0009253 GO:0009416 GO:0009583 GO:0009585 GO:0009881 GO:0016020 GO:0016021 GO:0016038 GO:0016056 GO:0016787 GO:0016798 GO:0016918 GO:0016998 GO:0018298 GO:0019076 GO:0019835 GO:0022400 GO:0030430 GO:0030507 GO:0030660 GO:0030867 GO:0042622 GO:0042742 GO:0045494 GO:0046872 GO:0050896 GO:0050953 GO:0051219 GO:0060041 GO:0060170 GO:0060342 GO:0071482 GO:0097381
170.070.5633.900.100.704ib4A GO:0001755 GO:0001819 GO:0001938 GO:0001965 GO:0002031 GO:0003007 GO:0003300 GO:0004871 GO:0004930 GO:0004993 GO:0005096 GO:0005506 GO:0005737 GO:0005886 GO:0005887 GO:0006182 GO:0006874 GO:0006939 GO:0007165 GO:0007186 GO:0007202 GO:0007205 GO:0007210 GO:0007507 GO:0007610 GO:0008144 GO:0008284 GO:0009055 GO:0010507 GO:0010513 GO:0014033 GO:0014065 GO:0014827 GO:0016020 GO:0016021 GO:0016310 GO:0019722 GO:0020037 GO:0022900 GO:0030054 GO:0030425 GO:0034220 GO:0035733 GO:0042310 GO:0042493 GO:0042597 GO:0043005 GO:0043025 GO:0043066 GO:0043123 GO:0043406 GO:0043547 GO:0043647 GO:0045202 GO:0046872 GO:0048598 GO:0050715 GO:0050795 GO:0051000 GO:0051209 GO:0051378 GO:0051781 GO:0055114 GO:0060548 GO:0070371 GO:0070374 GO:0070528 GO:0071418 GO:0071502 GO:1904015
180.070.5753.530.060.704s0vA GO:0004373 GO:0004871 GO:0004930 GO:0005886 GO:0005887 GO:0007165 GO:0007186 GO:0007200 GO:0007218 GO:0007268 GO:0007631 GO:0008188 GO:0010840 GO:0016020 GO:0016021 GO:0016499 GO:0017046 GO:0022410 GO:0032870 GO:0042277 GO:0045187 GO:0051480 GO:1901652


Consensus prediction of GO terms		 
Molecular Function GO:0005102 GO:0004553 GO:0042277 GO:0008528 GO:0005506 GO:0009055 GO:0020037 GO:0035251 GO:0042562 GO:0008289 GO:0045125
GO-Score 0.52 0.50 0.48 0.48 0.37 0.37 0.37 0.36 0.36 0.31 0.31
Biological Processes GO:0021937 GO:0048368 GO:0019827 GO:0021587 GO:0014032 GO:0048747 GO:0030182 GO:0042981 GO:0021766 GO:0042476 GO:0042306 GO:0043069 GO:0003337 GO:0008589 GO:1900182 GO:0072093 GO:0021532 GO:0010464 GO:0040014 GO:0016055 GO:0009798 GO:0061180 GO:0021695 GO:0050769 GO:0051797 GO:1902692 GO:0014002 GO:0003143 GO:0090189 GO:0036315 GO:0042636 GO:0045165 GO:2000648 GO:0048639 GO:0048730 GO:0070723 GO:0003309 GO:0007227 GO:0061213 GO:2000113 GO:0001775 GO:0050678 GO:0048514 GO:0051091 GO:0051101 GO:1904591 GO:0030856 GO:0051100 GO:0007418 GO:0046620 GO:0045596 GO:0002068 GO:0046824 GO:0003283 GO:0001667 GO:0048872 GO:0060242 GO:0031647 GO:0009967 GO:0090316 GO:0021536 GO:0045683 GO:0060972 GO:0021513 GO:0014904 GO:0097306 GO:0048854 GO:0007519 GO:0055123 GO:1903507 GO:0014812 GO:0060411 GO:0072036 GO:0060246 GO:0061371 GO:0003209 GO:0098542 GO:0019058 GO:0044248 GO:0044036 GO:0000270 GO:0006027 GO:0009617 GO:0019233 GO:0051931 GO:0007631 GO:0007268 GO:0007218 GO:0045944 GO:0022900 GO:0050802 GO:0009725 GO:0071495 GO:0042749 GO:0010243 GO:0007193 GO:0010629 GO:0007200 GO:0007204 GO:0035637 GO:0007155 GO:0097581 GO:0050926 GO:2000147 GO:0046850 GO:0030282 GO:0003158 GO:0045453 GO:0032844 GO:0030278 GO:0070167 GO:0072676 GO:0030334 GO:0051492 GO:0051345 GO:0043087 GO:0030031 GO:0071695 GO:0050921 GO:0003241 GO:0055017 GO:0032232 GO:0055008 GO:0090520 GO:0048660 GO:0061383
GO-Score 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.48 0.48 0.48 0.38 0.38 0.38 0.37 0.36 0.36 0.36 0.36 0.36 0.36 0.34 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31 0.31
Cellular Component GO:1903561 GO:0098588 GO:0030139 GO:0044853 GO:0044441 GO:0030659 GO:0012505 GO:0031253 GO:0033646 GO:0097458 GO:0005887 GO:0042597 GO:0005773 GO:0009986 GO:0098552
GO-Score 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.52 0.50 0.48 0.38 0.37 0.31 0.31 0.31

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]


Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.