Threading Zmax Znorm MUSTER 6.05 1.04 dPPAS 10.89 1.17 wdPPAS 10.90 1.17 wMUSTER 6.96 1.20 wPPAS 7.77 1.11 dPPAS2 19.28 1.84 PPAS 7.20 1.03 Env-PPAS 9.18 1.15 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=15546) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.23 0.56+-0.15 8.3+-4.5 9752 0.240 model2 -1.51 6084 0.183 model3 -1.22 8426 0.244 model4 -2.53 2459 0.066 model5 -1.80 4786 0.136 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).