Threading Zmax Znorm MUSTER 7.90 1.36 dPPAS 17.52 1.88 wdPPAS 23.12 2.49 wMUSTER 9.25 1.59 wPPAS 26.91 3.84 dPPAS2 39.99 3.81 PPAS 23.76 3.39 Env-PPAS 25.70 3.21 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=4518) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.29 0.44+-0.14 12.8+-4.2 896 0.037 model2 -2.08 604 0.046 model3 -2.66 529 0.026 model4 -3.28 325 0.014 model5 -2.90 260 0.020 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).