Threading Zmax Znorm MUSTER 5.17 0.89 dPPAS 6.76 0.73 wdPPAS 12.11 1.30 wMUSTER 5.19 0.89 wPPAS 12.80 1.83 dPPAS2 14.50 1.38 PPAS 9.56 1.37 Env-PPAS 14.42 1.80 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11295) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.42 0.34+-0.11 15.4+-3.4 1697 0.026 model2 -2.95 753 0.041 model3 -4.17 739 0.012 model4 -4.68 434 0.007 model5 -4.75 422 0.007 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).