Threading Zmax Znorm MUSTER 5.00 0.86 dPPAS 8.93 0.96 wdPPAS 16.23 1.75 wMUSTER 5.38 0.93 wPPAS 9.49 1.36 dPPAS2 15.28 1.46 PPAS 7.49 1.07 Env-PPAS 6.47 0.81 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=7776) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.33 0.34+-0.12 13.7+-4.0 1173 0.031 model2 -2.66 883 0.061 model3 -3.42 877 0.029 model4 -4.13 539 0.014 model5 -4.30 377 0.012 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).