Threading Zmax Znorm MUSTER 6.71 1.16 dPPAS 8.85 0.95 wdPPAS 9.19 0.99 wMUSTER 7.39 1.27 wPPAS 11.62 1.66 dPPAS2 14.21 1.35 PPAS 12.38 1.77 Env-PPAS 7.52 0.94 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=3012) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.43 0.43+-0.14 14.0+-3.9 753 0.070 model2 -2.95 568 0.041 model3 -3.70 284 0.020 model4 -3.41 282 0.026 model5 -2.45 165 0.068 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).