Threading Zmax Znorm MUSTER 6.03 1.04 dPPAS 9.52 1.02 wdPPAS 9.84 1.06 wMUSTER 6.85 1.18 wPPAS 10.91 1.56 dPPAS2 15.13 1.44 PPAS 10.50 1.50 Env-PPAS 8.02 1.00 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=10542) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.71 0.51+-0.15 10.9+-4.6 3765 0.148 model2 -3.87 753 0.017 model3 -3.87 753 0.017 model4 -4.13 616 0.013 model5 -4.50 486 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).