Threading Zmax Znorm MUSTER 4.32 0.75 dPPAS 8.57 0.92 wdPPAS 6.71 0.72 wMUSTER 4.52 0.78 wPPAS 4.25 0.61 dPPAS2 11.62 1.11 PPAS 5.28 0.75 Env-PPAS 5.67 0.71 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.50 0.42+-0.14 9.5+-4.6 8899 0.103 model2 -3.15 4906 0.054 model3 -4.83 854 0.010 model4 -3.74 2626 0.030 model5 -2.66 5910 0.088 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).