I-TASSER results

I-TASSER results for job id Rv2372c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (262 residues)
MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQAGRG
GLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDG
ARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEAT
ERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAV
GVLTSRWDASASDCEYCDVTRR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQAGRGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWDASASDCEYCDVTRR
Prediction	CCCEEHCCCCCCCCCCEEEHCHHHHHHHHHHHCCCCCEEEEEHCCCCCEEEEEEEEEHCCEEEEEEEEEHCCCCCCCCEEEEEHCCCCHHHHHHHHHHHHHCCCEEEEEEHCCEEHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEHCCCCCHHHHHHHHHHHCCCCCEEEEHCCCCCCCHHHCCCCCCCCEEEEHCCCCCCCHHHHHHHHHHCCEEEHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
Conf.Score	9985775888888995899787899999998758999589998799978999999975998999999985788899868999968887579999999999889889998855656567858999999999999999999989988975546889999999999866779889996899888878755678996899988999998999999999899899769987554589999999999998777888888767776789
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQAGRGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWDASASDCEYCDVTRR
Prediction	6522201045435563304045620300130140435230230134322130202213553020203343446523120000000124520330031001000320100204302231556325322520330032005114302002023124034005403732452010000026365304514454553000000002102350042037350310201630420100000000001111220545565364364468
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCEEHCCCCCCCCCCEEEHCHHHHHHHHHHHCCCCCEEEEEHCCCCCEEEEEEEEEHCCEEEEEEEEEHCCCCCCCCEEEEEHCCCCHHHHHHHHHHHHHCCCEEEEEEHCCEEHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEHCCCCCHHHHHHHHHHHCCCCCEEEEHCCCCCCCHHHCCCCCCCCEEEEHCCCCCCCHHHHHHHHHHCCEEEHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
MVAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQAGRGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWDASASDCEYCDVTRR

4l69A

1.00

0.92

0.93

3.29

MUSTER

V-AMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQ----GLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

1.00

0.93

4.24

dPPAS

-VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQG---GLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

0.95

0.89

0.93

4.93

wdPPAS

-VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSV---PPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

0.99

0.92

0.93

4.03

wMUSTER

A--MLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGG---LRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

0.95

0.89

0.93

5.17

wPPAS

V-AMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSV---PPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

1.00

0.93

6.60

dPPAS2

-VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQG---GLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

0.99

0.92

0.93

4.59

PPAS

V-AMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGG---LRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4l69A

0.99

0.92

0.93

5.64

Env-PPAS

V-AMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGG---LRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD--------------

4e8bA

0.24

0.22

0.92

3.07

MUSTER

--IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAE-----QDEGLKLNLHPRASNSINTLPLP-VERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL-------------

4e8bA

0.24

0.22

0.92

4.08

dPPAS

--IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAE-----QDEGLKLNLHPRASNSINTLPLP-VERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL-------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.97

Estimated TM-score = 0.85±0.08

Estimated RMSD = 3.9±2.7Å

Download Model 2

C-score=-2.02

Download Model 3

C-score=-1.66

Download Model 4

C-score=-0.70

Download Model 5

C-score=-2.19

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1nxzA	0.795	2.55	0.233	0.916
2	2egvA	0.787	2.12	0.225	0.866
3	1vhkC	0.764	2.75	0.292	0.889
4	3kw2A	0.761	2.78	0.242	0.878
5	1z85B	0.698	2.60	0.241	0.809
6	1v6zA	0.571	2.70	0.242	0.645
7	3gh7A	0.571	4.75	0.059	0.805
8	1m04A	0.563	4.75	0.051	0.794
9	1o7aA	0.559	4.76	0.068	0.794
10	3gyqA	0.559	4.40	0.107	0.741

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.68	24	2cx8A	SAH	Rep, Mult	175,176,177,198,199,200,201,202,203,220,222,223,225,226,227,229,232
2	0.04	2	1vhk0	III	Rep, Mult	93,96,97,100,101,102,136,137,140,141,143,224,225,226,227,228,230,231,235,238,239,241,242,248,249
3	0.02	1	1v2xA	PO4	Rep, Mult	87,89,90,201,228
4	0.02	1	2z8yO	XE	Rep, Mult	82,158,197,211
5	0.02	1	1v6z0	III	Rep, Mult	96,100,101,102,141,143,177,178,180,182,184,222,223,227,228,231,235,238,239,241
6	0.02	1	1z850	III	Rep, Mult	100,184,238,239,243

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.177	1zjrA	0.515	3.56	0.102	0.637	2.1.1.34	87,89,94,101,203
2	0.060	3gyqA	0.559	4.40	0.107	0.741	2.1.1.66	101,135
3	0.060	1b0pA	0.369	6.70	0.072	0.691	1.2.7.1	NA
4	0.060	3hm7B	0.465	4.68	0.048	0.660	3.5.2.5	230
5	0.060	2pdaA	0.419	5.89	0.087	0.699	1.2.7.1	NA
6	0.060	2vvnA	0.520	4.89	0.059	0.756	3.2.1.52	44
7	0.060	1m7jA	0.468	4.55	0.061	0.660	3.5.1.81	21
8	0.060	1c7sA	0.556	4.62	0.069	0.779	3.2.1.52	NA
9	0.060	3gipA	0.473	4.52	0.081	0.664	3.5.1.82	NA
10	0.060	3gh4A	0.572	4.74	0.060	0.809	3.2.1.52	NA
11	0.060	1e9yB	0.459	4.76	0.033	0.664	3.5.1.5	NA
12	0.060	3giqA	0.474	4.52	0.081	0.664	3.5.1.82	132,138
13	0.060	3d6nA	0.464	4.79	0.092	0.668	3.5.2.3	NA
14	0.060	1ie7C	0.459	4.70	0.058	0.660	3.5.1.5	NA
15	0.060	2vr2A	0.446	5.13	0.049	0.664	3.5.2.2	NA
16	0.060	2pffA	0.506	4.99	0.100	0.737	2.3.1.41,2.3.1.86	NA
17	0.060	1xc6A	0.476	4.58	0.037	0.664	3.2.1.23	30
18	0.060	2gjxA	0.555	4.67	0.077	0.779	3.2.1.52	NA
19	0.060	1xrtA	0.452	4.91	0.081	0.653	3.5.2.3	44
20	0.060	2ftwA	0.445	5.34	0.042	0.695	3.5.2.2	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.70	0.920	0.67	1.00	0.93	4l69A	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
1	0.48	0.808	2.57	0.24	0.93	1nxzA	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
2	0.47	0.827	2.13	0.24	0.92	4e8bA	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
3	0.42	0.779	2.51	0.22	0.89	4j3cB	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259
4	0.42	0.787	2.12	0.23	0.87	2egvA	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
5	0.41	0.573	2.73	0.24	0.65	1v6zA	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
6	0.38	0.773	2.74	0.26	0.89	3kw2A	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259
7	0.36	0.659	2.27	0.32	0.73	1vhkB	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
8	0.34	0.776	2.75	0.29	0.90	1vhkC	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
9	0.25	0.701	2.59	0.25	0.81	1z85B	GO:0005737 GO:0006364 GO:0008168 GO:0016740 GO:0032259 GO:0070042 GO:0070475
10	0.06	0.430	4.84	0.05	0.62	2icsA	GO:0016787 GO:0016810 GO:0046872
11	0.06	0.315	4.93	0.06	0.45	1qpnA	GO:0003824 GO:0004514 GO:0005618 GO:0005737 GO:0005886 GO:0009435 GO:0016740 GO:0016757 GO:0016763 GO:0019363 GO:0034213
12	0.06	0.272	5.56	0.06	0.42	1ev4A	GO:0004364 GO:0005634 GO:0005640 GO:0005737 GO:0005829 GO:0007568 GO:0008144 GO:0008152 GO:0016740 GO:0031667 GO:0042178 GO:0042493 GO:0043295
13	0.06	0.287	4.13	0.07	0.38	3cfyA	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0008134 GO:0043565
14	0.06	0.242	6.67	0.06	0.45	5et5A	GO:0003824 GO:0005634 GO:0005737 GO:0005829 GO:0005975 GO:0006000 GO:0006094 GO:0008152 GO:0016311 GO:0016787 GO:0030018 GO:0030054 GO:0042132 GO:0042578 GO:0046872 GO:0070062
15	0.06	0.225	5.79	0.11	0.39	1v2bB	GO:0005509 GO:0009507 GO:0009523 GO:0009535 GO:0009536 GO:0009579 GO:0009654 GO:0015979 GO:0016020 GO:0019898
16	0.06	0.191	4.40	0.04	0.26	2dlyA	GO:0000122 GO:0000166 GO:0004672 GO:0004713 GO:0004715 GO:0005102 GO:0005524 GO:0005634 GO:0005737 GO:0005886 GO:0006468 GO:0007169 GO:0016301 GO:0016310 GO:0016740 GO:0030154 GO:0031234 GO:0038083 GO:0042127 GO:0043231 GO:0045087 GO:0070062
17	0.06	0.131	3.52	0.03	0.16	1q08A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0008270 GO:0045893 GO:0046872
18	0.06	0.133	2.88	0.05	0.15	2e5qA	GO:0005634 GO:0005654 GO:0006351 GO:0006355 GO:0008270 GO:0016568 GO:0035064 GO:0035098 GO:0045814 GO:0046872 GO:0061087

Consensus prediction of GO terms

Molecular Function	GO:0070042
GO-Score	0.95
Biological Processes	GO:0070475
GO-Score	0.95
Cellular Component	GO:0005737
GO-Score	0.97

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.