Threading Zmax Znorm MUSTER 8.08 1.39 dPPAS 10.51 1.13 wdPPAS 11.94 1.28 wMUSTER 9.90 1.71 wPPAS 14.20 2.03 dPPAS2 18.40 1.75 PPAS 12.24 1.75 Env-PPAS 16.74 2.09 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=6777) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.56 0.42+-0.14 14.3+-3.8 754 0.047 model2 -3.15 753 0.026 model3 -2.37 753 0.057 model4 -2.50 753 0.050 model5 -3.60 748 0.017 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).