Threading Zmax Znorm MUSTER 4.94 0.85 dPPAS 6.83 0.73 wdPPAS 8.71 0.94 wMUSTER 5.54 0.96 wPPAS 9.09 1.30 dPPAS2 12.38 1.18 PPAS 7.71 1.10 Env-PPAS 7.59 0.95 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.89 0.39+-0.13 10.8+-4.6 6605 0.056 model2 -3.25 4114 0.039 model3 -3.68 3043 0.025 model4 -4.12 2002 0.016 model5 -3.93 2094 0.020 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).