Threading Zmax Znorm MUSTER 5.91 1.02 dPPAS 7.34 0.79 wdPPAS 5.45 0.59 wMUSTER 5.28 0.91 wPPAS 5.51 0.79 dPPAS2 11.46 1.09 PPAS 7.86 1.12 Env-PPAS 5.34 0.67 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.08 0.58+-0.14 7.6+-4.3 10661 0.389 model2 -3.35 2315 0.040 model3 -3.89 1530 0.023 model4 -4.33 1231 0.015 model5 -4.40 785 0.014 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).