I-TASSER results

I-TASSER results for job id Rv2235

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (271 residues)
MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLK
TLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVD
RGYVRPQVGSHVPPIPRLPVQTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAA
LTGVQLAGSYLQLIEDQPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEI
RARRREKAGSPPPDKPMTVEQKLADRYGRRR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIEDQPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRREKAGSPPPDKPMTVEQKLADRYGRRR
Prediction	CCCEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEHCCCEEEEHCEHCCCCCEEEEEEEEEHCCCCEEEEHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHCCCCCCCCCCCCCCCCCCEEEHCCHHHHHHHHCCCCCCCEEEHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
Conf.Score	9965444575699999999999999999997899999999999999999998689988765678877886556758999999996896799965655997759999978978998899986876787777888999999875999999977999888888778888885897899999999899878858997899998888888888898766999999999999999999999999999999987657777777655776666664579
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIEDQPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRREKAGSPPPDKPMTVEQKLADRYGRRR
Prediction	4530322233312222021112223112201212041252145215414643744225145125365344752311302030313343211022134533100100000216714300001010347665544544532724020201021335444434253763331011020520073172611200020236534314314224243452002011321102113321221002313544566576456664554655346436568
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCEEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEHCCCEEEEHCEHCCCCCEEEEEEEEEHCCCCEEEEHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHCCCCCCCCCCCCCCCCCCEEEHCCHHHHHHHHCCCCCCCEEEHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIEDQPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRREKAGSPPPDKPMTVEQKLADRYGRRR

5gaoE

0.08

0.07

0.94

1.22

dPPAS

-----------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

5gaoE

0.08

0.07

0.94

1.38

dPPAS2

-----------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

5gaoE

0.08

0.94

1.04

PPAS

---------------AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA--AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

3e5nA1

0.09

0.03

0.36

1.21

dPPAS2

---------------------------------------------------------------------------------------RGLIFGGKSAEDPQRFEPVLIGIDKQGQWHVNDPDSFLLHADDPARIALHRSGRGVALL---PGAQQQQLRPIQQALAQIDVVFPISLQGLLRMANLPFV------------------------------------------------------------------------------------

4bhrA

0.15

0.04

0.28

1.21

dPPAS2

--------------------------------------TAAQAYVRNVATAVEAERDPTTGALPQLPVANPPASVTQCNVTAN-NDGVNFTVTAQLTYG------SVSFDSSTGQFSFQL-------------------------------------------------------------------------------------------------------------------------------------------------------

2lp4A1

0.17

0.04

0.24

1.17

dPPAS2

MQ-----LNTDIINLFLETKDIMQEQLDAYKN-----AASFEYICNALRQLALETPSAVTRLSVVAKSEPQDEQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5eq2A1

0.10

0.04

0.41

1.17

dPPAS2

--------------------------------------------------------------RRATDTTPP-----------TITVPSDIIAYR----GEE-FEFYFEITDDSGQVKNIELNWLEYSEDNFNVPGNATSDNPLRVRVHGTVPLNEPIPADKNRAQFTRTIRAWDAA------GNVSSNITFVIKYR---------------------------------------------------------------------------

5fbhB

0.09

0.08

0.95

0.72

MUSTER

KNQFKSFLRTIPNDEHQATAMADIIEYFR---W-AADDDYGRPGIEKFREEAEE--RDIIDFSELISQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNIT-GKIWLASEAWASSSL-IAMPQYFHVVGGTIGFALK-AGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQFRPLCTGDEN---ISSVETPYIDYTH--LRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNF

4cfiA

0.09

0.07

0.86

0.82

dPPAS

----------SILQTASSGLTSLTNSLQRIRQLAVQASASDASALQQEVAQQISEVNRIASQTNYNGKNILDGSAGTLSFQVGANVGQTVSVDLTQSMSAA---KIGGGMVQTGQTLGTIKVAIDSSGAAWSSGSTGQE-----TTQINVVSDGKGGFTFTDQNNQ-----ALSSTAVTAVFGSSTAGTGTAASPSFQTLALSTSATSALS------------ATDQANATAMVAQINAVNKPQTVSNLDISTQTGAYQAMVSIDNA----

5flhA

0.11

0.06

0.52

0.58

wdPPAS

-----------------------------------------------IE----ATRHRARSFIPPEPGKPEKGLGDRAHLFGDLI---TIYAGGEQTENTFN---FFTCEGPKGEVFYITQGFVEDLEGEQHEKLLTPPKNSQVVGVAAGPGTPAEELGLPVRPFVPE-----KFRTVPEQYDVRFRPD----HQWHTGSIEGRKL-----------------------------------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-2.89

Estimated TM-score = 0.39±0.13

Estimated RMSD = 12.8±4.2Å

Download Model 2

C-score=-4.11

Download Model 3

C-score=-3.43

Download Model 4

C-score=-5.00

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5gaoE	0.675	3.95	0.080	0.867
2	1wxrA	0.399	5.43	0.059	0.616
3	5a9q1	0.398	6.44	0.040	0.716
4	3h09B	0.393	6.03	0.055	0.646
5	3syjA	0.393	5.86	0.064	0.635
6	4iw0A	0.392	5.14	0.025	0.565
7	3szeA	0.390	6.00	0.045	0.642
8	3i04A2	0.388	6.20	0.038	0.668
9	4bujB	0.385	6.16	0.069	0.664
10	5a22A	0.385	6.40	0.042	0.675

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.11	5	2h6bA	3C4	Rep, Mult	227,230
2	0.05	2	3serA	CA	Rep, Mult	34,36
3	0.05	2	4il6x	CLA	Rep, Mult	225,226
4	0.02	1	1g42A	CP2	Rep, Mult	99,100
5	0.02	1	2r4jA	IMD	Rep, Mult	32,33,85,134
6	0.02	1	5a43B	DMU	Rep, Mult	25,33
7	0.02	1	3k7tB	GP7	Rep, Mult	173,176,179
8	0.02	1	3rr5A	MG	Rep, Mult	162,246
9	0.02	1	3mq7E	CA	Rep, Mult	217,220
10	0.02	1	4q9iA	ALA	Rep, Mult	233,237
11	0.02	1	1mvyA	GLC	Rep, Mult	77,78,144,147,149
12	0.02	1	2o01H	CLA	Rep, Mult	114,118
13	0.02	1	3kziX	CLA	Rep, Mult	230,233
14	0.02	1	2yzjC	MG	Rep, Mult	91,108
15	0.02	1	2zpgB	TB0	Rep, Mult	217,267
16	0.02	1	3aodA	MIY	Rep, Mult	45,78,80

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1z0hB	0.271	6.54	0.038	0.494	3.4.24.69	159
2	0.060	1a31A	0.327	5.86	0.030	0.528	5.99.1.2	164
3	0.060	2a4zA	0.303	5.80	0.051	0.487	2.7.1.153	NA
4	0.060	2vuaA	0.266	6.62	0.025	0.494	3.4.24.69	164
5	0.060	2je8B	0.373	6.26	0.061	0.624	3.2.1.25	104
6	0.060	2zuwC	0.351	6.03	0.016	0.583	2.4.1.211	112
7	0.060	3c5wA	0.229	6.33	0.039	0.402	3.1.3.16	NA
8	0.060	3btaA	0.359	6.96	0.055	0.679	3.4.24.69	NA
9	0.060	2gq3A	0.349	5.73	0.035	0.539	2.3.3.9	NA
10	0.060	1vncA	0.286	6.37	0.024	0.502	1.11.1.10	206,208,210
11	0.060	1n63B	0.344	6.68	0.075	0.631	1.2.99.2	NA
12	0.060	1y8bA	0.285	6.27	0.047	0.498	2.3.3.9	NA
13	0.060	1h16A	0.353	6.13	0.036	0.598	2.3.1.54	NA
14	0.060	1rr8C	0.331	5.78	0.030	0.524	5.99.1.2	NA
15	0.060	1jqoA	0.345	5.86	0.051	0.557	4.1.1.31	NA
16	0.060	1cjyA	0.367	5.70	0.064	0.583	3.1.1.4,3.1.1.5	NA
17	0.060	1iduA	0.352	5.97	0.036	0.583	1.11.1.10	NA
18	0.060	1s46A	0.332	6.51	0.062	0.583	2.4.1.4	NA
19	0.060	3b8cB	0.362	5.87	0.047	0.583	3.6.3.6	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.10	0.675	3.95	0.08	0.87	5gaoE	GO:0000387 GO:0000398 GO:0000481 GO:0005634 GO:0005681 GO:0006397 GO:0008380 GO:0030529 GO:0045292 GO:0046540
1	0.06	0.393	5.86	0.06	0.63	3syjA	GO:0004175 GO:0004252 GO:0005576 GO:0006508 GO:0007155 GO:0008233 GO:0008236 GO:0009279 GO:0009986 GO:0016020 GO:0016021 GO:0016787 GO:0019867 GO:0042597 GO:0042802
2	0.06	0.400	5.51	0.06	0.62	3ak5A	GO:0004175 GO:0004252 GO:0005576 GO:0006508 GO:0008233 GO:0008236 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0016787 GO:0019867 GO:0042597
3	0.06	0.393	6.03	0.06	0.65	3h09B	GO:0004175 GO:0004252 GO:0005576 GO:0006508 GO:0008233 GO:0008236 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0016787 GO:0042597
4	0.06	0.282	6.68	0.07	0.52	4g33A	GO:0016165 GO:0016491 GO:0016702 GO:0042597 GO:0046872 GO:0051213 GO:0055114
5	0.06	0.399	5.43	0.06	0.62	1wxrA	GO:0004175 GO:0004252 GO:0005576 GO:0006508 GO:0008233 GO:0008236 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0016787 GO:0019867 GO:0042597
6	0.06	0.266	6.02	0.04	0.43	2d09A	GO:0004497 GO:0005506 GO:0016491 GO:0016705 GO:0020037 GO:0042440 GO:0046872 GO:0055114
7	0.06	0.204	6.78	0.04	0.38	4igdA	GO:0001867 GO:0002376 GO:0004252 GO:0005509 GO:0005576 GO:0005615 GO:0006508 GO:0006898 GO:0006956 GO:0008233 GO:0008236 GO:0016787 GO:0042803 GO:0045087 GO:0045916 GO:0046872 GO:0048306
8	0.06	0.344	6.23	0.04	0.58	4om9A	GO:0004175 GO:0004252 GO:0005576 GO:0006508 GO:0008233 GO:0008236 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0016787 GO:0019867 GO:0042597
9	0.06	0.236	6.34	0.04	0.40	1azwA	GO:0004177 GO:0005737 GO:0006508 GO:0008233 GO:0016787
10	0.06	0.390	6.00	0.04	0.64	3szeA	GO:0004175 GO:0004252 GO:0005576 GO:0006508 GO:0008233 GO:0008236 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0016787 GO:0019867 GO:0042597
11	0.06	0.255	6.48	0.04	0.45	2uuvC	GO:0003824 GO:0005777 GO:0006629 GO:0008609 GO:0008610 GO:0008611 GO:0016491 GO:0016614 GO:0016740 GO:0043178 GO:0044351 GO:0050660 GO:0055114 GO:0071949
12	0.06	0.287	6.58	0.05	0.52	1dabA	GO:0005576 GO:0007155 GO:0009279 GO:0009405 GO:0009986 GO:0016020 GO:0016021 GO:0019867 GO:0042597
13	0.06	0.398	6.44	0.04	0.72	5a9q1	GO:0000776 GO:0005487 GO:0005634 GO:0005635 GO:0005643 GO:0005829 GO:0006406 GO:0006409 GO:0006810 GO:0007062 GO:0007077 GO:0010827 GO:0015031 GO:0016032 GO:0016925 GO:0019083 GO:0031047 GO:0031080 GO:0051028 GO:0075733 GO:1900034
14	0.06	0.263	5.95	0.04	0.43	2iouG	GO:0007155 GO:0019867
15	0.06	0.212	6.37	0.03	0.37	4exlB	GO:0005886 GO:0006810 GO:0006817 GO:0015415 GO:0016020 GO:0016036 GO:0035435 GO:0042301
16	0.06	0.225	6.27	0.04	0.39	3hsqA	GO:0005737 GO:0006629 GO:0008610 GO:0008780 GO:0009245 GO:0016740 GO:0016746
17	0.06	0.225	6.67	0.03	0.41	1gvfB	GO:0003824 GO:0005829 GO:0005975 GO:0008270 GO:0009025 GO:0016829 GO:0016832 GO:0046872 GO:2001059
18	0.06	0.227	6.67	0.04	0.41	3dahC	GO:0000166 GO:0000287 GO:0004749 GO:0005524 GO:0005737 GO:0006015 GO:0009156 GO:0009165 GO:0016301 GO:0016310 GO:0016740 GO:0044249 GO:0046872

Consensus prediction of GO terms

Molecular Function	GO:0004175	GO:0008236
GO-Score	0.36	0.36
Biological Processes	GO:0019538
GO-Score	0.36
Cellular Component	GO:0030313	GO:0044462	GO:0019867
GO-Score	0.36	0.36	0.36

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.