Threading Zmax Znorm MUSTER 6.19 1.07 dPPAS 11.01 1.18 wdPPAS 23.15 2.49 wMUSTER 8.64 1.49 wPPAS 17.58 2.51 dPPAS2 33.13 3.16 PPAS 10.18 1.45 Env-PPAS 13.11 1.64 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=6267) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.52 0.65+-0.13 7.0+-4.1 4564 0.318 model2 -1.13 2159 0.173 model3 -0.90 2633 0.217 model4 -3.06 350 0.025 model5 -2.96 326 0.028 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).