Threading Zmax Znorm MUSTER 7.14 1.23 dPPAS 18.04 1.94 wdPPAS 29.34 3.15 wMUSTER 9.42 1.62 wPPAS 16.41 2.34 dPPAS2 29.84 2.84 PPAS 9.61 1.37 Env-PPAS 14.84 1.86 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -0.26 0.68+-0.12 6.3+-3.9 15954 0.378 model2 -2.91 1129 0.027 model3 -1.90 3195 0.073 model4 -1.82 3328 0.079 model5 -1.67 3421 0.092 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).