I-TASSER results

Input Sequence in FASTA format

>protein (134 residues)
MPLSDHEQRMLDQIESALYAEDPKFASSVRGGGFRAPTARRRLQGAALFIIGLGMLVSGV
AFKETMIGSFPILSVFGFVVMFGGVVYAITGPRLSGRMDRGGSAAGASRQRRTKGAGGSF
TSRMEDRFRRRFDE

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MPLSDHEQRMLDQIESALYAEDPKFASSVRGGGFRAPTARRRLQGAALFIIGLGMLVSGVAFKETMIGSFPILSVFGFVVMFGGVVYAITGPRLSGRMDRGGSAAGASRQRRTKGAGGSFTSRMEDRFRRRFDE
Prediction	CCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
Conf.Score	99889999999999999999798999987688988876545899999999999999999987545556889999999999999999986368878888888888888888888888887889999999999869
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MPLSDHEQRMLDQIESALYAEDPKFASSVRGGGFRAPTARRRLQGAALFIIGLGMLVSGVAFKETMIGSFPILSVFGFVVMFGGVVYAITGPRLSGRMDRGGSAAGASRQRRTKGAGGSFTSRMEDRFRRRFDE
Prediction	76346524420541163037413500540445544444332201010012323232211113333433332221231223133122111123444454665666655656666666443025324632553478
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120

                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
MPLSDHEQRMLDQIESALYAEDPKFASSVRGGGFRAPTARRRLQGAALFIIGLGMLVSGVAFKETMIGSFPILSVFGFVVMFGGVVYAITGPRLSGRMDRGGSAAGASRQRRTKGAGGSFTSRMEDRFRRRFDE

5id3A

0.15

0.13

0.92

1.00

wPPAS

MALSSREKKLLLQLENAETLLAPLHDAKRKIEQEAEAHTDRVAWAGFAASGVQTGLFARLTWWEYS----PVTYFATYSTVAATFGYYLYTQQSFE---PSARERVYTKQFYRRAQKQNF----IEKYNRLVTE

2mmuA

0.12

0.04

0.37

1.59

dPPAS2

--------------------------------------------SVWFVSLFIGLMLIGLIWLMVFQLLGPWNYAIAFAFMITGLLLTMRWHLE----------------------------------------

5id3A

0.12

0.96

1.01

PPAS

AALSSREKKLLLQLENAETLLAPLHDAKRKIEQEAEAHTDRVAWAGFAASGVQTGLFARLTWWEYS----PVTYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRRAQKQN-EKYNRLVTEVDELRNQ

1h2sB

0.14

0.05

0.37

1.52

dPPAS2

-------------------------------------------GAVFIFVGALTVLFGAIAYGEAAVQEAAVSAILGLIILLGINLGLVAATL-----------------------------------------

3v5sA1

0.16

0.07

0.46

1.50

dPPAS2

----------------------------------------MVILGVGYFLLGLILLYYGSDWFVPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDIS--------------------------------

5awwG

0.15

0.06

0.40

1.40

dPPAS2

--------------------------------------MDLLYTLVILFYLGVAGLLVYLVLVQETGGLYRLTVILGVVFAALALVIGLWPR------------------------------------------

2ndjA

0.10

0.06

0.60

1.36

dPPAS2

--------------------------------METTNGTETWYESLHAVLKALNATLHSNLLCRPGSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI---------------------

5cwmA1

0.13

0.11

0.85

0.84

MUSTER

-----DPEDELKRVEKLVKEAEELLRQAKEKG---SEEDLEKALRTAEEAAREAKKVLEQAEKEGDPEVALRAVELVVRVAELLLRIAK----------ESGSEEALERALRVAEEAARLAKRVLELAEKQG--

5id3A

0.10

1.00

0.73

dPPAS

EYKLSREKKLLLQLENAETLLAPLHDAKRKIEQEAEAHTDRVAWAGFAASGVQTGLFARLTWWEYIVEPVTYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRRAQKQNFDIEKYNRLVTEVDELRNQ

4qndA

0.17

0.10

0.60

0.96

wdPPAS

-------MALIERIGKALE---PQLYKLY--SHSEHALGLSLTTWLLYSFIALLWTIYGIYHKNPTIWVGNCLGFLMYVAMVVGIIAHTGGTY-----------------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.91

Estimated TM-score = 0.48±0.15

Estimated RMSD = 8.7±4.5Å

Download Model 2

C-score=-3.73

Download Model 3

C-score=-3.24

Download Model 4

C-score=-5.00

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5id3A	0.700	3.24	0.078	0.963
2	4aurA	0.596	2.91	0.093	0.806
3	4nqiA	0.575	3.43	0.064	0.821
4	4tqlA	0.573	3.50	0.036	0.828
5	2v0oA	0.572	3.69	0.027	0.813
6	4ke2A	0.569	3.35	0.073	0.813
7	1f31A3	0.566	3.60	0.033	0.806
8	3mk4A	0.566	3.90	0.032	0.843
9	1jadA	0.561	3.23	0.046	0.806
10	5bqnA	0.559	3.66	0.033	0.821

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.08	4	3ffzA	NA	Rep, Mult	17,21,22,23
2	0.06	3	1gu4A	NUC	Rep, Mult	9,10,13,14,16,17,18
3	0.06	3	3pp5A	CA	Rep, Mult	15,18
4	0.04	2	2wieC	CVM	Rep, Mult	86,87
5	0.04	2	1mz9B	VDY	Rep, Mult	72,75,79
6	0.02	1	1vd5A	GLY	Rep, Mult	53,72
7	0.02	1	4rynA	MPG	Rep, Mult	53,56,57,60,73
8	0.02	1	2a5lA	MG	Rep, Mult	24,27
9	0.02	1	3zqeB	DXC	Rep, Mult	46,53,72,79
10	0.02	1	3f1f2	MG	Rep, Mult	3,7
11	0.02	1	3ar4A	PTY	Rep, Mult	44,51,55
12	0.02	1	2yktA	III	Rep, Mult	24,27,28,30,31,119,121,125
13	0.02	1	1g42A	CA	Rep, Mult	5,8
14	0.02	1	1kzuE	BCL	Rep, Mult	78,81
15	0.02	1	2wse1	CLA	Rep, Mult	26,31
16	0.02	1	4dk7A	CA	Rep, Mult	120,121

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	3g61A	0.517	3.63	0.092	0.724	3.6.3.44	NA
2	0.060	3gtgB	0.482	4.76	0.073	0.828	2.7.7.6	74
3	0.060	1rr8C	0.326	5.23	0.051	0.582	5.99.1.2	NA
4	0.060	2zr3B	0.417	3.63	0.067	0.619	6.1.1.11	123
5	0.060	3kvnX	0.453	4.22	0.108	0.746	3.1.1.1	NA
6	0.060	1qhaA	0.427	4.23	0.061	0.716	2.7.1.1	NA
7	0.060	1eulA	0.420	4.69	0.046	0.716	3.6.3.8	NA
8	0.060	2nztA	0.472	3.83	0.074	0.694	2.7.1.1	NA
9	0.060	3c46B	0.447	4.91	0.062	0.791	2.7.7.6	46
10	0.060	2vuaA	0.276	5.50	0.026	0.545	3.4.24.69	50
11	0.060	2iw5A	0.444	4.32	0.019	0.664	1.-.-.-	NA
12	0.060	2pffA	0.506	4.22	0.025	0.821	2.3.1.41,2.3.1.86	NA
13	0.060	3b8eC	0.435	4.94	0.034	0.776	3.6.3.9	76
14	0.060	1z0hB	0.275	5.13	0.045	0.515	3.4.24.69	NA
15	0.060	3hmjA	0.489	4.56	0.050	0.828	2.3.1.86	NA
16	0.060	3b8cA	0.453	4.33	0.039	0.702	3.6.3.6	NA
17	0.060	3ikmD	0.451	5.08	0.033	0.843	2.7.7.7	NA
18	0.060	2vumB	0.416	4.41	0.026	0.679	2.7.7.6	74
19	0.060	3b8cB	0.453	4.33	0.039	0.702	3.6.3.6	84

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.18	0.700	3.24	0.08	0.96	5id3A	GO:0005262 GO:0015292 GO:0031305 GO:0036444 GO:0051560 GO:1990246
1	0.17	0.418	4.80	0.01	0.74	1xzpA	GO:0000166 GO:0002098 GO:0003924 GO:0005525 GO:0005622 GO:0005737 GO:0006400 GO:0008033 GO:0016787 GO:0030488 GO:0046872
2	0.08	0.499	4.39	0.07	0.80	2j68A	GO:0000166 GO:0003924 GO:0005525 GO:0005886 GO:0008289 GO:0016020 GO:0016021 GO:0016787
3	0.07	0.564	3.40	0.05	0.81	4nqiD	GO:0000281 GO:0000331 GO:0001891 GO:0005885 GO:0005905 GO:0006909 GO:0007009 GO:0009992 GO:0010324 GO:0031150 GO:0035091 GO:0042803 GO:0045335 GO:0046847 GO:0071476 GO:0072583
4	0.07	0.536	3.79	0.04	0.83	1y2oA	GO:0001726 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005913 GO:0007009 GO:0007409 GO:0008022 GO:0008093 GO:0008286 GO:0008360 GO:0009617 GO:0014069 GO:0015629 GO:0016020 GO:0016358 GO:0030141 GO:0030165 GO:0030175 GO:0030838 GO:0032956 GO:0038096 GO:0042802 GO:0042995 GO:0043005 GO:0043025 GO:0043197 GO:0048010 GO:0048167 GO:0051017 GO:0051764 GO:0061003 GO:0070062 GO:0070064 GO:0097481 GO:0098609 GO:0098641 GO:2000251
5	0.07	0.596	3.07	0.03	0.82	4aurA	GO:0005525
6	0.06	0.580	3.26	0.03	0.82	2d1lA	GO:0001701 GO:0002230 GO:0003779 GO:0003785 GO:0005102 GO:0005737 GO:0005856 GO:0005912 GO:0007009 GO:0007015 GO:0007399 GO:0007517 GO:0010960 GO:0015629 GO:0030036 GO:0030041 GO:0030282 GO:0032233 GO:0034334 GO:0042802 GO:0050680 GO:0051015 GO:0061333 GO:0071498 GO:0072001 GO:0072102 GO:0072160 GO:0098792 GO:2001013
7	0.06	0.478	4.27	0.04	0.78	3haiA	GO:0005543 GO:0005737 GO:0005768 GO:0005829 GO:0005886 GO:0006897 GO:0007015 GO:0008092 GO:0008289 GO:0016020 GO:0030054 GO:0030100 GO:0030137 GO:0030659 GO:0031410 GO:0032587 GO:0042995 GO:0043005 GO:0043209 GO:0043679 GO:0045202 GO:0045806 GO:0048471 GO:0048488 GO:0048666 GO:0048812 GO:0072657 GO:0090002 GO:0097320 GO:1900006
8	0.06	0.468	4.39	0.04	0.79	3qniA	GO:0005543 GO:0005737 GO:0005768 GO:0005829 GO:0005886 GO:0006897 GO:0007015 GO:0008092 GO:0008289 GO:0016020 GO:0030054 GO:0030100 GO:0030137 GO:0030659 GO:0031410 GO:0032587 GO:0042995 GO:0043005 GO:0043209 GO:0043679 GO:0045202 GO:0045806 GO:0048471 GO:0048488 GO:0048666 GO:0048812 GO:0072657 GO:0090002 GO:0097320 GO:1900006
9	0.06	0.525	3.89	0.06	0.78	4bneA	GO:0005737 GO:0005768 GO:0005769 GO:0005802 GO:0005829 GO:0005856 GO:0005886 GO:0005901 GO:0005925 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0030036 GO:0030054 GO:0030100 GO:0030659 GO:0031410 GO:0032587 GO:0042995 GO:0045806 GO:0055038 GO:0070300 GO:0070836 GO:0097320
10	0.06	0.491	4.29	0.05	0.81	3q0kD	GO:0005215 GO:0005654 GO:0005737 GO:0005768 GO:0005769 GO:0005829 GO:0005856 GO:0005886 GO:0005901 GO:0005911 GO:0005913 GO:0005925 GO:0006897 GO:0008092 GO:0008289 GO:0016020 GO:0019898 GO:0030036 GO:0030100 GO:0030659 GO:0031410 GO:0032587 GO:0036010 GO:0042802 GO:0042995 GO:0043231 GO:0045806 GO:0048858 GO:0055038 GO:0070062 GO:0070300 GO:0070836 GO:0072584 GO:0097320 GO:0098609 GO:0098641
11	0.06	0.440	4.28	0.06	0.72	2lemA	GO:0001523 GO:0001540 GO:0001932 GO:0001935 GO:0002740 GO:0005319 GO:0005543 GO:0005548 GO:0005576 GO:0005615 GO:0005634 GO:0005829 GO:0006629 GO:0006644 GO:0006656 GO:0006695 GO:0006810 GO:0006869 GO:0006898 GO:0007186 GO:0007229 GO:0007584 GO:0008035 GO:0008104 GO:0008202 GO:0008203 GO:0008211 GO:0008289 GO:0009986 GO:0010804 GO:0010873 GO:0010898 GO:0010903 GO:0015485 GO:0015914 GO:0017127 GO:0018158 GO:0018206 GO:0019433 GO:0019899 GO:0019915 GO:0030139 GO:0030300 GO:0030301 GO:0030325 GO:0031100 GO:0031103 GO:0031210 GO:0031410 GO:0032489 GO:0033344 GO:0033700 GO:0034115 GO:0034190 GO:0034191 GO:0034361 GO:0034364 GO:0034365 GO:0034366 GO:0034372 GO:0034375 GO:0034380 GO:0035025 GO:0042157 GO:0042158 GO:0042493 GO:0042627 GO:0042632 GO:0042802 GO:0043534 GO:0043627 GO:0043691 GO:0045499 GO:0045723 GO:0046470 GO:0050713 GO:0050728 GO:0050821 GO:0050919 GO:0051006 GO:0051180 GO:0051345 GO:0051346 GO:0051496 GO:0055091 GO:0055102 GO:0060192 GO:0060228 GO:0060354 GO:0060761 GO:0070062 GO:0070328 GO:0070508 GO:0070653 GO:0071813 GO:0072562 GO:1900026 GO:1903561
12	0.06	0.351	4.78	0.07	0.60	4xp9C	GO:0005328 GO:0005329 GO:0005330 GO:0005886 GO:0005887 GO:0006810 GO:0006836 GO:0015293 GO:0015872 GO:0016020 GO:0016021 GO:0019811 GO:0030431 GO:0042745 GO:0043005 GO:0046872 GO:0051583 GO:0055085 GO:0072488 GO:0098793 GO:0099509 GO:1990834
13	0.06	0.322	4.03	0.10	0.51	3zjcF	GO:0000166 GO:0003924 GO:0005525 GO:0005737 GO:0005811 GO:0042803
14	0.06	0.349	4.56	0.06	0.55	4hndA	GO:0000166 GO:0000287 GO:0002561 GO:0004430 GO:0005524 GO:0005739 GO:0005765 GO:0005768 GO:0005794 GO:0005829 GO:0005886 GO:0005887 GO:0006661 GO:0016020 GO:0016023 GO:0016301 GO:0016310 GO:0016740 GO:0030054 GO:0030425 GO:0030672 GO:0031083 GO:0031224 GO:0031410 GO:0031901 GO:0032403 GO:0035651 GO:0035838 GO:0042734 GO:0042995 GO:0043005 GO:0043025 GO:0043204 GO:0043231 GO:0043234 GO:0044231 GO:0045121 GO:0045202 GO:0046854 GO:0070382 GO:0098779
15	0.06	0.247	4.84	0.00	0.45	5a0pA	GO:0005576 GO:0006508 GO:0008233 GO:0008237 GO:0009405 GO:0016787 GO:0046872
16	0.06	0.326	4.85	0.02	0.58	4dcsA	GO:0000027 GO:0000166 GO:0003924 GO:0005525 GO:0005737 GO:0042254 GO:0043022
17	0.06	0.307	5.28	0.09	0.59	2p51A	GO:0000289 GO:0003676 GO:0003723 GO:0003729 GO:0004518 GO:0004527 GO:0004535 GO:0005634 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0016787 GO:0030014 GO:0030015 GO:0046872 GO:0090305 GO:0090503
18	0.06	0.377	4.96	0.04	0.67	5i0nA	GO:0000166 GO:0000287 GO:0002561 GO:0003796 GO:0003824 GO:0004430 GO:0005524 GO:0005739 GO:0005765 GO:0005768 GO:0005794 GO:0005829 GO:0005886 GO:0005887 GO:0006661 GO:0008152 GO:0009253 GO:0016020 GO:0016023 GO:0016301 GO:0016310 GO:0016740 GO:0016787 GO:0016798 GO:0016998 GO:0019835 GO:0030054 GO:0030425 GO:0030672 GO:0031083 GO:0031224 GO:0031410 GO:0031901 GO:0032403 GO:0035651 GO:0035838 GO:0042734 GO:0042742 GO:0042995 GO:0043005 GO:0043025 GO:0043204 GO:0043231 GO:0043234 GO:0044231 GO:0045121 GO:0045202 GO:0046854 GO:0070382 GO:0098779

Consensus prediction of GO terms

Molecular Function	GO:0017111	GO:0032561	GO:0032550	GO:0035639	GO:0005261	GO:0015291	GO:0015085	GO:0043169
GO-Score	0.47	0.47	0.47	0.47	0.35	0.35	0.35	0.34
Biological Processes	GO:0070588	GO:1990542	GO:0070509	GO:0006851	GO:0006874	GO:0001510	GO:0002097
GO-Score	0.35	0.35	0.35	0.35	0.35	0.34	0.34
Cellular Component	GO:0032592	GO:0034704	GO:0098800	GO:0031304
GO-Score	0.35	0.35	0.35	0.35

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv2169c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]