Threading Zmax Znorm MUSTER 4.81 0.83 dPPAS 7.53 0.81 wdPPAS 8.35 0.90 wMUSTER 5.05 0.87 wPPAS 7.45 1.06 dPPAS2 10.46 1.00 PPAS 7.04 1.01 Env-PPAS 7.74 0.97 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.72 0.40+-0.13 9.2+-4.6 8395 0.071 model2 -2.73 7018 0.070 model3 -4.34 1426 0.014 model4 -4.62 1257 0.011 model5 -3.21 4108 0.044 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).