Threading Zmax Znorm MUSTER 5.52 0.95 dPPAS 6.52 0.70 wdPPAS 6.97 0.75 wMUSTER 5.67 0.98 wPPAS 7.55 1.08 dPPAS2 11.60 1.11 PPAS 6.79 0.97 Env-PPAS 5.63 0.70 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.57 0.52+-0.15 8.3+-4.5 14081 0.229 model2 -3.37 1685 0.038 model3 -2.56 1480 0.085 model4 -2.24 6339 0.118 model5 -3.78 1585 0.025 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).