Threading Zmax Znorm MUSTER 3.61 0.62 dPPAS 6.59 0.71 wdPPAS 5.49 0.59 wMUSTER 3.69 0.64 wPPAS 4.70 0.67 dPPAS2 13.04 1.24 PPAS 5.19 0.74 Env-PPAS 6.01 0.75 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.05 0.37+-0.13 12.5+-4.3 6361 0.064 model2 -3.59 3809 0.037 model3 -4.09 2314 0.023 model4 -4.54 787 0.014 model5 -4.26 1862 0.019 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).