Threading Zmax Znorm MUSTER 4.00 0.69 dPPAS 5.19 0.56 wdPPAS 7.12 0.77 wMUSTER 4.47 0.77 wPPAS 6.18 0.88 dPPAS2 12.55 1.20 PPAS 5.37 0.77 Env-PPAS 5.70 0.71 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.77 0.31+-0.10 14.4+-3.7 3038 0.029 model2 -4.23 2097 0.018 model3 -4.35 1402 0.016 model4 -4.71 1103 0.011 model5 -4.81 981 0.010 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).