Threading Zmax Znorm MUSTER 4.71 0.81 dPPAS 7.17 0.77 wdPPAS 6.39 0.69 wMUSTER 5.16 0.89 wPPAS 6.58 0.94 dPPAS2 13.39 1.28 PPAS 9.15 1.31 Env-PPAS 7.90 0.99 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=15546) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.01 0.29+-0.09 16.4+-3.0 2031 0.019 model2 -3.98 1081 0.019 model3 -4.84 1006 0.008 model4 -4.85 848 0.008 model5 -4.76 795 0.009 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).