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I-TASSER results for job id Rv2077A

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

 Input Sequence in FASTA format
 Predicted Secondary Structure
 Predicted Solvent Accessibility
 Predicted Normalized B-facotr
 Top 10 threading templates used by I-TASSER
 Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)
 Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)
 Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)
  Ligand binding sites

Rank C-score Cluster
size		 PDB
Hit		 Lig
Name		 Download
Complex		 Ligand Binding Site Residues
10.08 13 3wuvA III Rep, Mult 61,64,65,68,71,72,75
20.06 10 1fosH NUC Rep, Mult 41,44,45,48,52
30.05 8 1nwqC NUC Rep, Mult 54,55,58,59,61,62,63
40.05 9 2e42B NUC Rep, Mult 43,44,47,48,50,51,52,54
50.04 8 3gjoC III Rep, Mult 78,79,82
60.04 6 2jj1G PIT Rep, Mult 86,89,90,93,94
70.04 7 2ceiA ZN Rep, Mult 20,65,68
80.03 6 4de6A ACD Rep, Mult 24,62,63,66,70
90.03 5 1gu5B NUC Rep, Mult 50,51,54,55,57,58,59,61
100.03 6 3ogiB III Rep, Mult 44,48,49,51,52,55,59
110.03 5 3arcB CLA Rep, Mult 13,75,78,79
120.02 4 5da5C GOA Rep, Mult 19,20,23,65
130.02 4 2hp2B KE4 Rep, Mult 42,44
140.01 1 1bf5A QNA Rep, Mult 34,35,44,47
150.01 1 1vsgA UUU Rep, Mult 9,12,13,16,19,72
160.01 1 2wm2A CL Rep, Mult 6,10,13,47
170.01 1 3a52A MG Rep, Mult 94,96
180.01 1 3oeeY III Rep, Mult 29,30,31,32,44,46,47
190.01 1 3fk7A 4DM Rep, Mult 86,90
200.01 1 3m4oA C7P Rep, Mult 74,75,78

Download the all possible binding ligands and detailed prediction summary.
Download the templates clustering results.
(a)C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)Cluster size is the total number of templates in a cluster.
(c)Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column.
Mult is the complex structures with all potential binding ligands in the cluster.

  Enzyme Commission (EC) numbers and active sites

RankCscoreECPDB
Hit		TM-scoreRMSDaIDENaCovEC NumberActive Site Residues
10.1611wt6B0.4752.110.0450.5762.7.11.175
20.1331cxzB0.5253.120.1130.7072.7.11.1323,25
30.1043e7kH0.4861.720.0360.5562.7.11.1NA
40.0801wu0A0.4663.140.1040.6673.6.3.14NA
50.0602ahmE0.2852.910.0290.3742.7.7.48NA
60.0603b8eC0.5393.700.1220.8493.6.3.954
70.0601fziA0.5543.760.0770.7881.14.13.25NA
80.0601x75B0.4132.960.0350.5765.99.1.3NA
90.0602dq3A0.6083.060.0530.7986.1.1.11NA
100.0601y8pA0.5422.690.0790.7482.7.11.2NA
110.0602zr3B0.6123.170.0330.8186.1.1.1122,58
120.0602iw5A0.5673.610.0320.9091.-.-.-NA
130.0603e04D0.5593.360.1130.8494.2.1.274
140.0602np0A0.5753.670.0420.8893.4.24.695,79
150.0601syyA0.5393.080.0420.7371.17.4.1NA
160.0601mhyD0.5503.800.0660.8081.14.13.25NA
170.0601wleB0.5344.100.0820.9196.1.1.11NA
180.0601xdpA0.5482.860.0110.7782.7.4.1NA
190.0601clqA0.5563.070.0740.8382.7.7.723,63
200.0603i9wA0.6432.860.0930.8792.7.13.3NA
210.0601y2mB0.5833.640.1440.8594.3.1.24NA
220.0601rx0A0.5444.020.0720.8381.3.99.-NA
230.0601w27A0.5833.660.1240.8694.3.1.24NA

(a)CscoreEC is the confidence score for the EC number prediction. CscoreEC values range in between [0-1];
where a higher score indicates a more reliable EC number prediction.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided
by length of the query protein.

  Gene Ontology (GO) terms

Homologous GO templates in PDB 
RankCscoreGOTM-scoreRMSDaIDENaCovPDB HitAssociated GO Terms
00.280.5311.580.120.613b5nA GO:0000149 GO:0005484 GO:0005768 GO:0005802 GO:0005886 GO:0005935 GO:0006887 GO:0006893 GO:0006897 GO:0006906 GO:0012505 GO:0016020 GO:0016021 GO:0016192 GO:0030658 GO:0031201
10.250.4661.850.020.531dh3A GO:0000785 GO:0000790 GO:0000975 GO:0000978 GO:0000980 GO:0001102 GO:0001190 GO:0001666 GO:0003677 GO:0003690 GO:0003700 GO:0003705 GO:0005634 GO:0005654 GO:0005667 GO:0005719 GO:0005739 GO:0005759 GO:0006351 GO:0006355 GO:0006366 GO:0006468 GO:0007179 GO:0007219 GO:0007409 GO:0007568 GO:0007595 GO:0007613 GO:0007623 GO:0008134 GO:0008361 GO:0008542 GO:0010033 GO:0010629 GO:0010944 GO:0014823 GO:0019899 GO:0021983 GO:0030154 GO:0030424 GO:0030544 GO:0030879 GO:0032916 GO:0033363 GO:0033762 GO:0034670 GO:0035035 GO:0035094 GO:0035497 GO:0035729 GO:0036120 GO:0036276 GO:0040018 GO:0042493 GO:0042752 GO:0042802 GO:0042981 GO:0043065 GO:0043565 GO:0044212 GO:0045600 GO:0045672 GO:0045893 GO:0045899 GO:0045944 GO:0046887 GO:0046889 GO:0048145 GO:0048511 GO:0050821 GO:0055025 GO:0060251 GO:0060428 GO:0060430 GO:0060509 GO:0071294 GO:0071363 GO:0071398 GO:0071560 GO:1900273 GO:1901215 GO:1902065 GO:1990090 GO:1990314 GO:1990589 GO:1990763
20.250.5461.750.000.622npsA GO:0000149 GO:0000226 GO:0005484 GO:0005794 GO:0005802 GO:0006887 GO:0006906 GO:0009986 GO:0016020 GO:0016021 GO:0016192 GO:0031201 GO:0035493 GO:0042996 GO:0043001 GO:0090161 GO:1901998
30.210.5441.250.050.614wy4A GO:0000149 GO:0005484 GO:0005737 GO:0005764 GO:0005765 GO:0005768 GO:0005769 GO:0005829 GO:0005886 GO:0006810 GO:0006892 GO:0006906 GO:0006914 GO:0015031 GO:0016020 GO:0016021 GO:0016192 GO:0019869 GO:0030667 GO:0031201 GO:0031901 GO:0031902 GO:0031982 GO:0035577 GO:0043308 GO:0043312 GO:0046718 GO:0048471 GO:0055037 GO:0070062 GO:0070254 GO:0097352 GO:0098594 GO:1903076 GO:1903531 GO:1903595
40.210.4851.890.050.602n9bA GO:0000122 GO:0000166 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0001726 GO:0003677 GO:0003682 GO:0003700 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005547 GO:0005634 GO:0005667 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005938 GO:0006351 GO:0006355 GO:0006366 GO:0006810 GO:0007165 GO:0008360 GO:0008652 GO:0010691 GO:0016020 GO:0016459 GO:0030027 GO:0030705 GO:0030898 GO:0031527 GO:0032433 GO:0042802 GO:0042995 GO:0043565 GO:0045899 GO:0051015 GO:0051489 GO:0060002 GO:0060261 GO:1903833
50.160.4940.950.040.531gk6A GO:0000122 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0001948 GO:0003677 GO:0003682 GO:0003700 GO:0003725 GO:0005198 GO:0005200 GO:0005212 GO:0005634 GO:0005667 GO:0005737 GO:0005777 GO:0005829 GO:0005856 GO:0005882 GO:0005886 GO:0005925 GO:0006351 GO:0006355 GO:0006366 GO:0006928 GO:0008022 GO:0008652 GO:0010628 GO:0010691 GO:0010977 GO:0014002 GO:0016032 GO:0030049 GO:0031012 GO:0031252 GO:0042802 GO:0042995 GO:0043005 GO:0043565 GO:0045103 GO:0045109 GO:0045111 GO:0045899 GO:0060020 GO:0060261 GO:0060395 GO:0070062 GO:0070307 GO:0097110 GO:1903833 GO:1990254
60.150.6402.820.080.892y3aB GO:0001678 GO:0005634 GO:0005925 GO:0005942 GO:0006810 GO:0007165 GO:0008134 GO:0008286 GO:0010506 GO:0014065 GO:0015031 GO:0016303 GO:0019903 GO:0030833 GO:0030971 GO:0032869 GO:0034976 GO:0036092 GO:0036312 GO:0042325 GO:0042993 GO:0043551 GO:0045785 GO:0045944 GO:0046935 GO:0046982 GO:0051492 GO:0090003
70.140.5171.710.080.601l4aA GO:0016020 GO:0016021 GO:0016192 GO:0030054 GO:0030672 GO:0031410 GO:0043005 GO:0045202
80.140.5501.560.040.623basB GO:0000122 GO:0000166 GO:0000790 GO:0000978 GO:0000981 GO:0001080 GO:0001084 GO:0001135 GO:0001190 GO:0001191 GO:0003677 GO:0003682 GO:0003700 GO:0003774 GO:0003779 GO:0005516 GO:0005524 GO:0005634 GO:0005667 GO:0005737 GO:0006351 GO:0006355 GO:0006366 GO:0008652 GO:0010691 GO:0016459 GO:0030016 GO:0032982 GO:0042802 GO:0043565 GO:0045899 GO:0060261 GO:1903833
90.110.5101.990.030.623cveA GO:0005102 GO:0005737 GO:0005886 GO:0007216 GO:0007623 GO:0014069 GO:0016020 GO:0030054 GO:0030425 GO:0031802 GO:0032947 GO:0035094 GO:0035256 GO:0035418 GO:0042220 GO:0042802 GO:0043005 GO:0043025 GO:0043198 GO:0045202 GO:0045211 GO:0046982 GO:0060076 GO:0097110 GO:0097481
100.110.6863.280.070.933cwgB GO:0000790 GO:0000978 GO:0000981 GO:0001077 GO:0001103 GO:0001228 GO:0001659 GO:0001754 GO:0003677 GO:0003700 GO:0004871 GO:0004879 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005743 GO:0005829 GO:0005886 GO:0006351 GO:0006355 GO:0006366 GO:0006606 GO:0006953 GO:0007165 GO:0007259 GO:0007568 GO:0008134 GO:0008283 GO:0008285 GO:0010033 GO:0010628 GO:0010730 GO:0014070 GO:0016310 GO:0019221 GO:0019827 GO:0019901 GO:0019903 GO:0019953 GO:0030522 GO:0031490 GO:0031730 GO:0032355 GO:0032870 GO:0033210 GO:0034097 GO:0035259 GO:0035278 GO:0040014 GO:0042493 GO:0042517 GO:0042593 GO:0042755 GO:0042802 GO:0043066 GO:0043434 GO:0043565 GO:0044212 GO:0044320 GO:0044321 GO:0045471 GO:0045747 GO:0045820 GO:0045893 GO:0045944 GO:0046902 GO:0046983 GO:0048708 GO:0051726 GO:0060019 GO:0060259 GO:0060396 GO:0060397 GO:0060548 GO:0070102 GO:0071345 GO:0071407 GO:0090575 GO:0097009 GO:1901215 GO:1902728 GO:1902895 GO:1904685 GO:2000637 GO:2000737 GO:2001171 GO:2001223
110.110.7382.570.080.921i49A GO:0001726 GO:0005525 GO:0005737 GO:0005829 GO:0005886 GO:0005913 GO:0005938 GO:0006928 GO:0007264 GO:0019904 GO:0030032 GO:0030036 GO:0030742 GO:0031529 GO:0032588 GO:0034315 GO:0048365 GO:0070273 GO:0098609 GO:0098641
120.110.6713.090.020.931yvlB GO:0000122 GO:0000790 GO:0000978 GO:0000979 GO:0000983 GO:0001937 GO:0002053 GO:0003340 GO:0003677 GO:0003690 GO:0003700 GO:0004871 GO:0005164 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0005913 GO:0006351 GO:0006355 GO:0006357 GO:0006915 GO:0007165 GO:0007259 GO:0008015 GO:0016032 GO:0016525 GO:0019899 GO:0030424 GO:0030425 GO:0033209 GO:0034097 GO:0035456 GO:0035458 GO:0042802 GO:0042803 GO:0042981 GO:0043124 GO:0043434 GO:0043542 GO:0045893 GO:0045944 GO:0046725 GO:0048471 GO:0048661 GO:0051591 GO:0051607 GO:0060333 GO:0060334 GO:0060337 GO:0060338 GO:0061326 GO:0071345 GO:0071407 GO:0072136 GO:0072162 GO:0072308 GO:0098609 GO:0098641
130.100.6693.410.070.944e68A GO:0000790 GO:0000978 GO:0000981 GO:0001077 GO:0001103 GO:0001228 GO:0001659 GO:0001754 GO:0003677 GO:0003700 GO:0004871 GO:0004879 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005743 GO:0005829 GO:0005886 GO:0006351 GO:0006355 GO:0006366 GO:0006606 GO:0006953 GO:0007165 GO:0007259 GO:0007568 GO:0008134 GO:0008283 GO:0008285 GO:0010033 GO:0010628 GO:0010730 GO:0014070 GO:0016310 GO:0019221 GO:0019827 GO:0019901 GO:0019903 GO:0019953 GO:0030522 GO:0031490 GO:0031730 GO:0032355 GO:0032870 GO:0033210 GO:0034097 GO:0035259 GO:0035278 GO:0040014 GO:0042493 GO:0042517 GO:0042593 GO:0042755 GO:0042802 GO:0043066 GO:0043434 GO:0043565 GO:0044212 GO:0044320 GO:0044321 GO:0045471 GO:0045747 GO:0045820 GO:0045893 GO:0045944 GO:0046902 GO:0046983 GO:0048708 GO:0051726 GO:0060019 GO:0060259 GO:0060396 GO:0060397 GO:0060548 GO:0070102 GO:0071345 GO:0071407 GO:0090575 GO:0097009 GO:1901215 GO:1902728 GO:1902895 GO:1904685 GO:2000637 GO:2000737 GO:2001171 GO:2001223
140.100.6413.030.060.915jdoA GO:0016020 GO:0016021
150.100.6702.900.080.902v0oA GO:0001786 GO:0005546 GO:0005886 GO:0005905 GO:0006897 GO:0010324 GO:0016020 GO:0030136 GO:0035091 GO:0048268 GO:0072583 GO:0072659
160.090.6883.240.070.951y1uA GO:0000255 GO:0000979 GO:0001553 GO:0001779 GO:0001938 GO:0003677 GO:0003700 GO:0004871 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006101 GO:0006103 GO:0006105 GO:0006107 GO:0006351 GO:0006355 GO:0006357 GO:0006549 GO:0006573 GO:0006600 GO:0006631 GO:0007165 GO:0007259 GO:0007565 GO:0007595 GO:0008284 GO:0018108 GO:0019218 GO:0019221 GO:0019530 GO:0019903 GO:0019915 GO:0030155 GO:0030856 GO:0030879 GO:0032825 GO:0033026 GO:0033077 GO:0038161 GO:0040014 GO:0040018 GO:0042104 GO:0043029 GO:0043066 GO:0043434 GO:0043536 GO:0045086 GO:0045579 GO:0045588 GO:0045621 GO:0045647 GO:0045931 GO:0045944 GO:0045954 GO:0046449 GO:0046543 GO:0046544 GO:0048541 GO:0050729 GO:0060376 GO:0060397 GO:0060740 GO:0060742 GO:0061180 GO:0070668 GO:0071345 GO:0071407 GO:0097011
170.090.6443.060.060.935c1fA GO:0001786 GO:0005547 GO:0005737 GO:0005826 GO:0005829 GO:0005856 GO:0007049 GO:0007067 GO:0051301 GO:0070273 GO:1903475
180.090.6942.560.040.934wpcB GO:0005096 GO:0005546 GO:0005737 GO:0005933 GO:0007165 GO:0007231 GO:0010314 GO:0010447 GO:0030479 GO:0032266 GO:0043547 GO:0070273 GO:0080025
190.070.5251.620.060.614ll8E GO:0003723 GO:0003729 GO:0005783 GO:0005789 GO:0005934 GO:0006810 GO:0007533 GO:0008298 GO:0016020 GO:0048309 GO:0051028
200.070.7042.770.020.883ibpA GO:0000166 GO:0000796 GO:0003677 GO:0005524 GO:0005525 GO:0005737 GO:0005829 GO:0006260 GO:0007049 GO:0007059 GO:0007062 GO:0009295 GO:0030261 GO:0042802 GO:0051301
210.070.5093.100.060.691uusA GO:0003677 GO:0003700 GO:0004871 GO:0005634 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0007165 GO:0010468 GO:0010628 GO:0030587 GO:0031149 GO:0031154 GO:0042803 GO:0044351 GO:0045892
220.070.5124.030.090.854iggB GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034332 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0051015 GO:0051149 GO:0051291 GO:0071681 GO:0090136 GO:0098641 GO:2000146 GO:2001045 GO:2001240 GO:2001241
230.070.5273.320.050.791ya9A GO:0001523 GO:0001540 GO:0001937 GO:0002021 GO:0005319 GO:0005543 GO:0005576 GO:0005615 GO:0005634 GO:0005783 GO:0005794 GO:0005829 GO:0005886 GO:0006629 GO:0006641 GO:0006695 GO:0006707 GO:0006810 GO:0006869 GO:0006874 GO:0006898 GO:0006979 GO:0007186 GO:0007263 GO:0008104 GO:0008201 GO:0008203 GO:0008289 GO:0010468 GO:0010544 GO:0010873 GO:0010875 GO:0015485 GO:0015909 GO:0016020 GO:0016209 GO:0017038 GO:0017127 GO:0019068 GO:0019433 GO:0019934 GO:0030195 GO:0030516 GO:0030828 GO:0031012 GO:0031103 GO:0032374 GO:0032489 GO:0032805 GO:0033344 GO:0033700 GO:0034361 GO:0034362 GO:0034363 GO:0034364 GO:0034372 GO:0034374 GO:0034375 GO:0034380 GO:0034382 GO:0034384 GO:0034447 GO:0042157 GO:0042158 GO:0042159 GO:0042311 GO:0042627 GO:0042632 GO:0042802 GO:0042803 GO:0043407 GO:0043524 GO:0043537 GO:0043691 GO:0044794 GO:0045541 GO:0046889 GO:0046911 GO:0048156 GO:0048844 GO:0050728 GO:0050750 GO:0051000 GO:0051044 GO:0051055 GO:0051651 GO:0055088 GO:0055089 GO:0060228 GO:0060999 GO:0061000 GO:0070062 GO:0070326 GO:0071813 GO:0072358 GO:0072562 GO:0090370 GO:0097113 GO:0097114 GO:0098869 GO:1900221 GO:1901214 GO:1901215 GO:1901216 GO:1901627 GO:1901628 GO:1901630 GO:1901631 GO:1902004 GO:1902430 GO:1902947 GO:1902951 GO:1902952 GO:1902995 GO:1902998 GO:1902999 GO:1903001 GO:1903002 GO:1903561
240.070.4733.370.040.724y5uA GO:0000122 GO:0000790 GO:0000979 GO:0002296 GO:0002829 GO:0003677 GO:0003700 GO:0004871 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0006357 GO:0007165 GO:0019221 GO:0019903 GO:0032481 GO:0033598 GO:0034097 GO:0035771 GO:0042127 GO:0042802 GO:0043565 GO:0045121 GO:0045944 GO:0048295 GO:0060443 GO:0070301 GO:1902170
250.070.4873.640.080.764y5wA GO:0000122 GO:0000790 GO:0000979 GO:0002296 GO:0002829 GO:0003677 GO:0003700 GO:0004871 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0006357 GO:0007165 GO:0019221 GO:0019903 GO:0032481 GO:0033598 GO:0034097 GO:0035771 GO:0042127 GO:0042802 GO:0043565 GO:0045121 GO:0045944 GO:0048295 GO:0060443 GO:0070301 GO:1902170
260.070.4822.870.070.704k1nA GO:0001541 GO:0001669 GO:0005198 GO:0005737 GO:0005794 GO:0005829 GO:0005856 GO:0005886 GO:0005911 GO:0005912 GO:0005913 GO:0005915 GO:0005925 GO:0007015 GO:0007155 GO:0007163 GO:0007406 GO:0007568 GO:0008013 GO:0008584 GO:0014070 GO:0014704 GO:0015629 GO:0016020 GO:0016264 GO:0016342 GO:0016600 GO:0017166 GO:0030027 GO:0030054 GO:0031103 GO:0034613 GO:0042127 GO:0042475 GO:0043066 GO:0043231 GO:0043297 GO:0043627 GO:0044822 GO:0045295 GO:0045296 GO:0045880 GO:0046982 GO:0051015 GO:0051291 GO:0071681 GO:0090136 GO:2000146 GO:2001045 GO:2001240 GO:2001241
270.060.3554.870.030.723ik2A GO:0000272 GO:0004553 GO:0046872


Consensus prediction of GO terms		 
Molecular Function GO:0005484 GO:0000149 GO:0033613 GO:0031072 GO:0001085 GO:0001158 GO:0000981 GO:0019899 GO:0008200 GO:0017081 GO:0042623 GO:0032559 GO:0001134 GO:0003779 GO:0035639 GO:0001083 GO:1901981 GO:0032550 GO:0032403 GO:0000146 GO:0042802 GO:0001190 GO:0000978
GO-Score 0.57 0.57 0.50 0.50 0.50 0.50 0.50 0.50 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.41 0.41 0.41
Biological Processes GO:0006906 GO:0098876 GO:0006892 GO:0043068 GO:0071229 GO:0048639 GO:0048667 GO:0060548 GO:0006935 GO:0014009 GO:0042127 GO:0040014 GO:0032941 GO:0071248 GO:0071559 GO:0002763 GO:0045598 GO:1901214 GO:0071396 GO:0010043 GO:0071375 GO:0045670 GO:0035728 GO:0021536 GO:0036119 GO:0048286 GO:1900271 GO:0048732 GO:0036293 GO:0007632 GO:0007178 GO:0071636 GO:0046890 GO:0016310 GO:0048144 GO:0048812 GO:0014013 GO:0032910 GO:1990089 GO:0060487 GO:0035270 GO:0043279 GO:0071363 GO:0032535 GO:0055024 GO:0014070 GO:0007623 GO:0045834 GO:0070542 GO:0008306 GO:0031647 GO:0045844 GO:0006464 GO:0061564 GO:0007589 GO:0006915 GO:0007010 GO:0043001 GO:0007030 GO:0043623 GO:0090003 GO:0007017 GO:0051223 GO:1903593 GO:0097576 GO:0002446 GO:0002283 GO:0043306 GO:0030260 GO:0002447 GO:0016236 GO:0002278 GO:0050729 GO:0019058 GO:0051048 GO:0010688 GO:0032109 GO:1903832 GO:0046394 GO:0006520 GO:0022604 GO:0001079 GO:0090294 GO:0046847 GO:0060491 GO:1901566 GO:0045899
GO-Score 0.57 0.55 0.55 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.41
Cellular Component GO:0016021 GO:0031201 GO:0030133 GO:0005933 GO:0030427 GO:0090575 GO:0044429 GO:0000791 GO:0043005 GO:0005802 GO:0005765 GO:0005770 GO:0042582 GO:0010008 GO:1903561 GO:0030667 GO:0031253 GO:0015629 GO:0044430 GO:0031252 GO:0099568 GO:0030175 GO:0000790 GO:0005829
GO-Score 0.57 0.57 0.55 0.55 0.55 0.50 0.50 0.50 0.50 0.46 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.42 0.41 0.37

(a)CscoreGO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)TM-score is a measure of global structural similarity between query and template protein.
(c)RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d)IDENa is the percentage sequence identity in the structurally aligned region.
(e)Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on CscoreGO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]


Please cite the following articles when you use the I-TASSER server:
1. J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2. J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.