I-TASSER results

I-TASSER results for job id Rv2054

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (237 residues)
MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPN
MYARGGRARCITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALV
LSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPA
DIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARCITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
Prediction	CCEEEEEHCCEEEEEEEEHCCCCCCCCEEEEHCCCCCCCHHHHHHHHHHHHHCCEEEEHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHCHHHHHHHHHHCCCCCEEEEHCCCCCCCCHHHHHCCCCCEEEEEHCCCCCCHHHHHHHHHHHHHHCCCEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
Conf.Score	967999859968999999869999975899986999989899999999999898999866899988998866999998667899999999999999986998996899965766799999866789789997798999887886668977899985799999689999999999979999999959999888889987776667777789999999999999999999868888999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 \| \| \| \| \| \| \| \| \| \| \| MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARCITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
Prediction	745051617714030000205574410000000102011420240043006310000000012443424413520451254254025003200410373552431000000010020001013330200000001223542640560301000000253412373054025105737260302002403000113436545454444412450054015202654553055466668
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCEEEEEHCCEEEEEEEEHCCCCCCCCEEEEHCCCCCCCHHHHHHHHHHHHHCCEEEEHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHCHHHHHHHHHHCCCCCEEEEHCCCCCCCCHHHHHCCCCCEEEEEHCCCCCCHHHHHHHHHHHHHHCCCEEEEHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARCITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRHLSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP

4zi5A

0.26

0.25

0.96

2.84

MUSTER

MTKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDGKVAAIGFCFGGATCLELARTGLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGSH--GIPGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.24

0.23

0.96

3.45

dPPAS

ARKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDSKVAAIGFCFGGATCLELARAPLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGSHGI--PGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.25

0.24

0.96

3.71

wdPPAS

MRKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDSKVAAIGFCFGGATCLELARAPLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGS--HGIPGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.25

0.24

0.96

3.50

wMUSTER

MRKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDGKVAAIGFCFGGATCLELARTGLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGSH--GIPGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.25

0.24

0.96

3.97

wPPAS

MRKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDSKVAAIGFCFGGATCLELARAPLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGSH--GIPGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.24

0.23

0.96

5.68

dPPAS2

ARKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDSKVAAIGFCFGGATCLELARAPLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGSHGI--PGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.25

0.24

0.96

3.66

PPAS

MTKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDSKVAAIGFCFGGATCLELARAPLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGSH--GIPGLAYDATAEARSWTAMCNLFSELFG-------

4zi5A

0.25

0.24

0.96

4.20

Env-PPAS

MTKVDYTDGATRCIGEFHWDEGSGPRPGVVVFPEAFGLNDHAKERARRLADLGFAALAADMHGDAQDAASLSSTIQGYYGDRAHWRRRAQAALDALTAQPEVDGKVAAIGFCFGGATCLELARAPLTAIVTFHGGLLPEMAGDAGRIQSSVLVCHGADDPLVDETMKAVMDEFRRDKVDWQVLYLGNAVHSFTDPLAGS--HGIPGLAYDATAEARSWTAMCNLFSELFG-------

1zi8A

0.24

0.22

0.93

2.67

MUSTER

MLGISIQSYDGHTFGALVGSPAKAPAPVIVIAQDIFGVNAFMRETVSWLVDQGYAAVCPDLYARQAPGTALREQAYKLWQDMEAGVGDLEAAIRYARHQPYSNGKVGLVGYSLGGALAFLVASKGVDRAVGYYGVGLEKQLNKVPEVKHPALFHMGGQDHFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTGSS---------GYVASAAALANERTLDFLVPLQS-------

1zi8A

0.23

0.22

0.93

3.31

dPPAS

TEGISIQSYDGHTFGALVGSPAKAPAPVIVIAQDIFGVNAFMRETVSWLVDQGYAAVCPDLYARQAPGTALQAYKLWQAFDMEAGVGDLEAAIRYARHQPYSNGKVGLVGYSLGGALAFLVASKGVDRAVGYYGVGLEKQLNKVPEVKHPALFHMGGQDHFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTGSS---------GYVASAAALANERTLDFLVPLQS-------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 4 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.75

Estimated TM-score = 0.81±0.09

Estimated RMSD = 4.2±2.8Å

Download Model 2

C-score=-0.81

Download Model 3

C-score=-0.66

Download Model 4

C-score=-1.72

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4zi5A	0.938	1.03	0.237	0.962
2	4zv9A	0.814	2.06	0.259	0.894
3	3f67A	0.813	2.10	0.235	0.899
4	1zi8A	0.808	2.41	0.249	0.916
5	3f98A	0.792	3.36	0.115	0.962
6	3k2iA2	0.785	2.71	0.239	0.899
7	4hxeB	0.779	2.83	0.173	0.911
8	1ve6A	0.770	2.55	0.171	0.882
9	4q3kA	0.770	2.84	0.127	0.899
10	3wlaA	0.768	2.69	0.120	0.907

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.23	13	3f98A	NTJ	Rep, Mult	34,35,111,112,113,135,159,190,191
2	0.05	3	1u8eA	UUU	Rep, Mult	17,19,54,56,57,58
3	0.03	2	3fytE	XYP	Rep, Mult	188,191,192
4	0.03	2	2bgrA	UUU	Rep, Mult	4,13,58,60,61
5	0.03	2	2h1iA	ZN	Rep, Mult	133,159,162,190
6	0.02	1	1tqhA	4PA	Rep, Mult	34,35,37,41,112,113,190
7	0.02	1	4ao7A	ZN	Rep, Mult	183,216
8	0.02	1	1x70A	UUU	Rep, Mult	109,152,153,154
9	0.02	1	1xfdB	UUU	Rep, Mult	223,227,230
10	0.02	1	3muoA	ZPR	Rep, Mult	31,56,109,111,112,133,190,218,222
11	0.02	1	4bzzA	ACT	Rep, Mult	48,52,222
12	0.02	1	1tk3B	NAG	Rep, Mult	9,64,88

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.581	1dinA	0.809	2.34	0.245	0.911	3.1.1.45	112,159,190
2	0.259	3cn7A	0.681	2.58	0.141	0.789	3.1.1.1	159,190
3	0.258	1auoA	0.696	2.66	0.119	0.806	3.1.1.1	159,190
4	0.258	1i6wB	0.574	3.04	0.150	0.688	3.1.1.3	113,159,190
5	0.209	2ocgA	0.679	2.99	0.135	0.810	3.1.-.-	114,118,159,166,190
6	0.206	1jjfA	0.702	2.99	0.183	0.844	3.2.1.8	37,41,60,113
7	0.190	2h1iA	0.665	3.30	0.124	0.819	3.1.1.1	136
8	0.116	1fj2A	0.705	3.06	0.143	0.844	3.1.4.39	NA
9	0.100	3fcxB	0.721	3.26	0.158	0.882	3.1.2.12	NA
10	0.075	1vkhA	0.662	3.17	0.124	0.814	3.5.1.9	84,86
11	0.067	3esbA	0.554	3.90	0.105	0.713	3.1.1.74	NA
12	0.067	3gbsA	0.541	3.71	0.082	0.688	3.1.1.74	NA
13	0.066	3dcnA	0.539	3.78	0.085	0.696	3.1.1.74	NA
14	0.060	1l7aA	0.753	2.63	0.155	0.861	3.1.1.72,3.1.1.41	NA
15	0.060	1orvA	0.750	3.07	0.131	0.890	3.4.14.5	159,190
16	0.060	1f6wA	0.728	3.12	0.119	0.869	3.1.1.13,3.1.1.3	NA
17	0.060	1lpsA	0.718	3.33	0.110	0.878	3.1.1.3	88
18	0.060	1aknA	0.727	3.22	0.118	0.878	3.1.1.13,3.1.1.3	NA
19	0.060	2jbwD	0.755	2.70	0.154	0.865	3.7.1.-	190
20	0.060	2qr5A	0.767	2.58	0.166	0.882	3.4.19.1	95
21	0.060	1e5tA	0.758	3.11	0.170	0.907	3.4.21.26	95
22	0.060	1z68A	0.737	3.03	0.124	0.878	3.4.21.-	159,190
23	0.060	1hlgA	0.732	3.18	0.129	0.869	3.1.1.3	228
24	0.060	1jjiA	0.739	2.47	0.166	0.840	3.1.1.1	NA
25	0.060	1r9mB	0.742	3.16	0.127	0.890	3.4.14.5	159,190
26	0.060	1yr2A	0.729	3.10	0.156	0.869	3.4.21.26	159
27	0.060	1k8qA	0.734	2.92	0.139	0.861	3.1.1.3	228
28	0.060	2bklB	0.750	3.10	0.153	0.903	3.4.21.26	NA
29	0.060	1vlqA	0.740	3.04	0.165	0.865	3.1.1.41	NA
30	0.060	2b4kA	0.734	3.34	0.159	0.899	3.1.1.43	NA
31	0.060	1gz7A	0.719	3.41	0.114	0.886	3.1.1.3	NA
32	0.060	3fvrA	0.754	2.83	0.163	0.873	3.1.1.6	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.45	0.821	2.04	0.26	0.90	4zv9A	GO:0016787
1	0.37	0.805	2.34	0.24	0.91	1dinA	GO:0008806 GO:0016787 GO:0019439 GO:0052689
2	0.30	0.705	3.06	0.14	0.84	1fj2A	GO:0002084 GO:0004622 GO:0005737 GO:0005739 GO:0005829 GO:0006629 GO:0006631 GO:0008474 GO:0016298 GO:0016787 GO:0042997 GO:0050999 GO:0070062
3	0.27	0.759	2.31	0.18	0.86	2o2gA	GO:0016787
4	0.24	0.722	2.42	0.15	0.82	3visA	GO:0003847 GO:0015996 GO:0016042 GO:0046872 GO:0047746
5	0.23	0.771	2.86	0.13	0.90	4q3kB	GO:0006508 GO:0008152 GO:0008236 GO:0016787
6	0.22	0.754	2.70	0.15	0.86	2jbwB	GO:0009820 GO:0016787 GO:0019608
7	0.22	0.717	3.13	0.17	0.85	4fhzA	GO:0016787
8	0.21	0.715	3.29	0.18	0.87	3dohA	GO:0002084 GO:0005737 GO:0008474 GO:0016787 GO:0052689
9	0.21	0.717	2.43	0.15	0.82	4eb0A	GO:0003847 GO:0016042 GO:0016787 GO:0050525
10	0.18	0.825	2.09	0.23	0.91	3f67A	GO:0016787
11	0.18	0.725	2.58	0.16	0.83	4cg3A	GO:0003847 GO:0015996 GO:0016042 GO:0016787 GO:0047746 GO:0050525
12	0.18	0.675	2.86	0.15	0.80	3ksrA	GO:0004252 GO:0006508 GO:0008236 GO:0016787
13	0.16	0.778	2.89	0.24	0.90	3hlkB	GO:0000038 GO:0001676 GO:0005102 GO:0005739 GO:0005759 GO:0006637 GO:0016290 GO:0016787 GO:0016790 GO:0035338 GO:0047617 GO:0052689 GO:0070062
14	0.15	0.771	2.92	0.12	0.90	4bzwA	GO:0008152 GO:0016787 GO:0042802
15	0.14	0.743	2.94	0.18	0.89	4n5hX	GO:0008152 GO:0016787
16	0.13	0.696	2.66	0.12	0.81	1auoA	GO:0016787 GO:0052689
17	0.10	0.680	2.98	0.17	0.80	4lheA	GO:0016787 GO:0047372 GO:0052689
18	0.09	0.671	2.75	0.17	0.78	4ke6E	GO:0016787 GO:0047372 GO:0052689
19	0.08	0.699	2.86	0.12	0.83	3h04A	GO:0008152 GO:0016787
20	0.07	0.680	3.15	0.14	0.82	1mt3A	GO:0004177 GO:0006508 GO:0008233 GO:0016787
21	0.07	0.481	3.90	0.08	0.65	4c20B	GO:0005737 GO:0005975 GO:0005996 GO:0006004 GO:0008736 GO:0016853 GO:0016861 GO:0019317 GO:0030145 GO:0042355 GO:0046872
22	0.07	0.431	5.46	0.05	0.70	4nf7A	GO:0000272 GO:0004553 GO:0005975 GO:0008152 GO:0008810 GO:0016787 GO:0016798 GO:0030245 GO:0030246 GO:0030247
23	0.06	0.356	4.57	0.07	0.51	4rs3A	GO:0005886 GO:0006810 GO:0008643 GO:0016020 GO:0030246 GO:0071322

Consensus prediction of GO terms

Molecular Function	GO:0016790	GO:0098599	GO:0004620	GO:0043169	GO:0008806
GO-Score	0.59	0.59	0.59	0.47	0.36
Biological Processes	GO:0032768	GO:0042159	GO:0090005	GO:0032787	GO:0098734	GO:0035601	GO:0044255	GO:0042996	GO:0051224	GO:0046149	GO:0006787	GO:0044712	GO:0015994
GO-Score	0.59	0.59	0.59	0.59	0.59	0.59	0.59	0.59	0.59	0.47	0.47	0.47	0.47
Cellular Component	GO:0031988	GO:1903561	GO:0043231	GO:0044444
GO-Score	0.59	0.59	0.59	0.59

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
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