Threading Zmax Znorm MUSTER 5.77 1.00 dPPAS 8.90 0.96 wdPPAS 8.60 0.92 wMUSTER 5.41 0.93 wPPAS 7.09 1.01 dPPAS2 18.59 1.77 PPAS 7.37 1.05 Env-PPAS 5.84 0.73 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.26 0.56+-0.15 6.6+-4.0 12928 0.271 model2 -2.93 2574 0.051 model3 -1.65 7752 0.183 model4 -2.76 2700 0.061 model5 -4.00 841 0.018 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).