Threading Zmax Znorm MUSTER 4.17 0.72 dPPAS 9.20 0.99 wdPPAS 6.64 0.71 wMUSTER 4.04 0.70 wPPAS 4.28 0.61 dPPAS2 15.29 1.46 PPAS 4.95 0.71 Env-PPAS 5.50 0.69 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.86 0.49+-0.15 10.3+-4.6 14095 0.189 model2 -2.53 5425 0.097 model3 -4.84 692 0.010 model4 -2.95 4380 0.064 model5 -4.07 1408 0.021 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).