I-TASSER results

I-TASSER results for job id Rv2033c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (280 residues)
MLDRYGTDVLAAGGRRRPRSVEHPVELGMVVEDAETGYVGAVVRVEYGRIDLEDRYGKTR
GFPLGPGYLLDGLPVILTAPRCAAAAGPRRTASGSVAVPGARARVARASRIYVEGRHDAE
LIAAVWGADLRIEGVVVEHLGGVDDLVEIVAKFRPGPRRRLGVLVDHLVAGSKEARIAEV
VRRGPGGSDTLVVGHPYVDIWQAVKPQRVGLAAWPRVPRHIEWKHGVCDALGWPHADQAD
IAAAWRRIRSQVRDWTDLEPALIGRVEELIDFVTQPAGDE

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 \| \| \| \| \| \| \| \| \| \| \| \| \| \| MLDRYGTDVLAAGGRRRPRSVEHPVELGMVVEDAETGYVGAVVRVEYGRIDLEDRYGKTRGFPLGPGYLLDGLPVILTAPRCAAAAGPRRTASGSVAVPGARARVARASRIYVEGRHDAELIAAVWGADLRIEGVVVEHLGGVDDLVEIVAKFRPGPRRRLGVLVDHLVAGSKEARIAEVVRRGPGGSDTLVVGHPYVDIWQAVKPQRVGLAAWPRVPRHIEWKHGVCDALGWPHADQADIAAAWRRIRSQVRDWTDLEPALIGRVEELIDFVTQPAGDE
Prediction	CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHCCCCCEEEEEEEHCCEEEEHCCCCCEEEHCCCCCEEHCCEEEEEHCCCCCCCCCCCCCCCCEEEHCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEEEHCCCCCCHHHHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHCCCCCCEEEHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
Conf.Score	9887888878899888999998777788679986899678999998677898758997887568885786886789866898899887777776577589876545565578864357899999876654566689985788776999999869999974788734368998899999999978889878997898643665447634488789999999875688899989999987669999999998678854468899999999865434899999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 \| \| \| \| \| \| \| \| \| \| \| \| \| \| MLDRYGTDVLAAGGRRRPRSVEHPVELGMVVEDAETGYVGAVVRVEYGRIDLEDRYGKTRGFPLGPGYLLDGLPVILTAPRCAAAAGPRRTASGSVAVPGARARVARASRIYVEGRHDAELIAAVWGADLRIEGVVVEHLGGVDDLVEIVAKFRPGPRRRLGVLVDHLVAGSKEARIAEVVRRGPGGSDTLVVGHPYVDIWQAVKPQRVGLAAWPRVPRHIEWKHGVCDALGWPHADQADIAAAWRRIRSQVRDWTDLEPALIGRVEELIDFVTQPAGDE
Prediction	7644224210445455555436140435000002642000000112432020103444434130330001134303033245565644523231233077241320351201010311040024013440311000013041123045205614233521000001001532413400430373451410000000200001002254141631171246461141004213033654630240043014305414403250042023001102435878
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHCCCCCEEEEEEEHCCEEEEHCCCCCEEEHCCCCCEEHCCEEEEEHCCCCCCCCCCCCCCCCEEEHCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEEEHCCCCCCHHHHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHCCCCCCEEEHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
MLDRYGTDVLAAGGRRRPRSVEHPVELGMVVEDAETGYVGAVVRVEYGRIDLEDRYGKTRGFPLGPGYLLDGLPVILTAPRCAAAAGPRRTASGSVAVPGARARVARASRIYVEGRHDAELIAAVWGADLRIEGVVVEHLGGVDDLVEIVAKFRPGPRRRLGVLVDHLVAGSKEARIAEVVRRGPGGSDTLVVGHPYVDIWQAVKPQRVGLAAWPRVPRHIEWKHGVCDALGWPHADQADIAAAWRRIRSQVRDWTDLEPALIGRVEELIDFVTQPAGDE

3onqA

0.17

0.09

0.52

1.46

dPPAS2

----------------------------------------------------------------------------------------------------------------------ADILDLLSGHTDTIERLAFELLTNTDDRVVSLNILGWQGDFNCFAIG--GVPSASLASTSLAIRKALGGEHVVIGTY--------------GTFLLALACQGVTPEVTCTAVPAFSEDEPAGASHALRETFSLQARADELERALLGDDYAREELYRGENPDD

3tywA2

0.20

0.04

0.19

1.39

dPPAS2

----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ICELLGIPRHDLEFFRDVTRISGSRNSTAEQVSGGLFGLLGGLVAERREEPRDD

4i6kA

0.14

0.12

0.86

0.72

MUSTER

MND-FSTQDHSIETARYAPDYEATVQ-SFISHLDEHNFTHGVLV---PSFLGTNNQAMLNAIQQYPDR----KGIAVVQHTTTFNELVNLKAQGIVGV---RLNLFGLNLPALNTPDWQKFLRNVESLNW-----QVELHAPPKYLVQLLPQLNEYSFD---VVIDHFPVKGIEDPDYQKFLSLLNVKQHWIK----VSGFYRLG------ATPSNINIAQQAYNIFKEKGFWPHTQHETYEDAIKAFKQIVFDKHEQCLILNQNPTELFGF--------

1q57A1

0.15

0.11

0.76

0.99

dPPAS

VWNFGESNGRYSALTARGISKETCQKAGYWIAKVDG--------VMYQVADYRDQNGNIVSQKVRDK---DKNFKTTGSHKSDAL-------------FGKHLWNGGKKIVVTEGEIDMLTVMELQDCKY----PVVSLGHGASAAKKTCAANYEDQFEQIILMFD---MDEAGRKAVEEAAQVLPAGKVRVAVLPCKDANECHLNG-----------HDREIMEQVWNAGPWIPDGVVSALSLRERIREHLSSE-------------------------

4i6kA

0.15

0.12

0.79

0.73

wdPPAS

MND-FSTQDHSIETARYAPDYEATVQ-SFISHLDEHNFTHGVLV-NNQAMLIQQYPDR--------------KGIAVVQHTTTFNELVNLKAQG---IVGVRLNLFGLNLPALNTPDWQKFLRNVE-------NWQVELHAPPKYLVQLLPQLNEYSFD---VVIDHFPVKGIEDPDYQKFLSLLNVKQHWIKG-QAYIFKEKGFLHKL----W-----GSD----------WPHESLITYEDAIKAFKQIVFDKHEQCLILNQNPTELFGF--------

4i6kA

0.16

0.13

0.81

0.67

wMUSTER

V---FSTQDHSIETARYAPDYEATVQ-SFISHLDEHNFTHGVLVTNNQAMLIQQYPDR--------------KGIAVVQHTTTFNELVNLKAQGIVGV---RLNLFGLNLPALNTPDWQKFLRNVE--SL---NWQVELHAPPKYLVQLLPQLNSFD-----VVIDHFPVKGIEDPDYQKFLSLLNVKQHWIKGFNINIAQQAYNIEKGFLHKW-----GSD----------WPHTQHETYEDAIKAFKQIVFDKHEQCLILNQNPTELFGF--------

4i6kA

0.16

0.13

0.79

0.57

wPPAS

MND-FSTQDHSIETARYAPDYEATVQ-SFISHLDEHNFTHGVLVTNNQAMLIQQYPDRLKGIAV-----VQ--------HTTTFNELVNLKAQGIVGV-----------RLNLFGLNNTPDWQKFL----NVENWQVELHAPPKYLVQLLPQLNEYSFD---VVIDHFPVKGIEDPDYQKFLSLLNVKQHWIKGQQAYIFKEKGFLHKL----W-----GSD----------WPHESLITYEDAIKAFKQIVFDKHEQCLILNQNPTELFGF--------

3oepA1

0.22

0.04

0.18

1.35

dPPAS2

-----------------------------------------------------------------------------------------------------------------------------------VRGFYLRFGEGVSELAEALLRAPP-PGGVLYLEYDPRRLS--RGRLLRLLKGLP-----------------------------------------------------------------------------------------------

2ffiA

0.16

0.14

0.87

0.70

PPAS

LHLTFSRGLNLASQRRYAPNYDAPLG-DYLGQLRAHGFSHGVL-VQ-PSFLGTDNRYLLSALQTVPGQLR-G----VVLERDVEQATLAEARLGVRGV-----RLNLGQDPDLTGAQWRPLLERIG--EQ---GWHVELHRQVADIPVLVRALQPYGLD---IVIDHFARRGLGQPGFAELLTLSGRGKVWVSG-----------IYRLQGSPEENLAFARQALCALEAHYGWPHTQHESFGSAVEQFEALGCSAQLRQALLLDTARALFGFELE-----

3q8dA

0.17

0.14

0.80

0.69

Env-PPAS

GWQRF---VL----HSRPW-----SETSLMLDVFTEES-GRVRLVAKGA-----RSKRSTLKGA----LQPFTPLLLR-------FGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLE-----YETRFSEL--FFDYLHCIQSLA-GVTGTPEPALRR-----FELALLGHLGYGVNFTHCAGSGEPVDTMTYRYREEKGFIASVVIDNKT--FTGRQLKALNAREFPDADTLRAAKRFTRMA-----LKPYLLKSRELFRQFM-------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.86

Estimated TM-score = 0.49±0.15

Estimated RMSD = 10.3±4.6Å

Download Model 2

C-score=-2.53

Download Model 3

C-score=-4.84

Download Model 4

C-score=-2.95

Download Model 5

C-score=-4.07

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4i6kA	0.745	2.62	0.127	0.836
2	4dlfA	0.709	3.26	0.083	0.850
3	2ffiA	0.706	3.01	0.134	0.825
4	2qahA	0.679	3.60	0.109	0.846
5	4hjwA	0.671	4.11	0.089	0.871
6	4mupA	0.670	3.58	0.122	0.839
7	2dvtA	0.665	3.89	0.092	0.850
8	2f6kA	0.661	3.88	0.096	0.850
9	4b90A	0.659	3.69	0.073	0.829
10	4infA	0.658	3.87	0.113	0.850

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.12	6	3qy6A	FE	Rep, Mult	102,138,166,195
2	0.04	2	3dg3A	MG	Rep, Mult	102,138,166
3	0.04	2	4jyeA	1N7	Rep, Mult	34,35,36,37,249
4	0.02	1	4i6kA	CIT	Rep, Mult	3,16,17,46,102,104,140,167
5	0.02	1	3ij6D	NA	Rep, Mult	125,133,135
6	0.02	1	1qhyA	MG	Rep, Mult	95,166
7	0.02	1	1mwoA	ZN	Rep, Mult	32,35,240,245
8	0.02	1	3id7A	ZN	Rep, Mult	133,167,195
9	0.02	1	2b0qA	MG	Rep, Mult	257,271
10	0.02	1	2dvuC	GRE	Rep, Mult	139,142,232
11	0.02	1	1nuiA	MG	Rep, Mult	114,166
12	0.02	1	1pokB	ASN	Rep, Mult	139,167,169
13	0.02	1	1r2rD	DMS	Rep, Mult	24,25,234
14	0.02	1	3ibsA	MG	Rep, Mult	93,95
15	0.02	1	3v1pB	BMP	Rep, Mult	3,42,75,77,140,141,233,234
16	0.02	1	1eywA	PEL	Rep, Mult	249,259,262
17	0.02	1	2v0nA	MG	Rep, Mult	118,166,168
18	0.02	1	3csvA	ZN	Rep, Mult	114,117

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.184	1tqxA	0.506	4.33	0.073	0.689	5.1.3.1	NA
2	0.067	1dvjA	0.526	4.08	0.099	0.700	4.1.1.23	NA
3	0.067	1m5wF	0.539	4.40	0.060	0.750	2.6.99.2	141,232
4	0.066	2h6rB	0.499	4.31	0.095	0.679	5.3.1.1	NA
5	0.066	1v5xA	0.478	4.24	0.092	0.650	5.3.1.24	166
6	0.066	1hg3A	0.507	4.31	0.108	0.693	5.3.1.1	NA
7	0.066	3exrA	0.508	4.35	0.096	0.704	4.1.1.85	170
8	0.066	1tqjC	0.492	4.25	0.068	0.668	5.1.3.1	139
9	0.066	2v81A	0.484	4.22	0.070	0.661	4.1.2.21	NA
10	0.066	1nsjA	0.486	4.25	0.070	0.664	5.3.1.24	166
11	0.066	3f4wA	0.510	3.99	0.127	0.675	4.1.2.-	NA
12	0.066	1w0mA	0.510	4.35	0.102	0.700	5.3.1.1	NA
13	0.066	2yw3E	0.473	4.20	0.105	0.639	4.1.2.14	NA
14	0.066	1jfxA	0.492	4.27	0.090	0.671	3.2.1.17	NA
15	0.066	1mxsA	0.487	4.11	0.082	0.650	4.1.2.14	NA
16	0.066	1xi3A	0.466	4.37	0.124	0.643	2.5.1.3	NA
17	0.060	2qt3B	0.620	4.58	0.089	0.854	3.5.99.4	268
18	0.060	1a4lA	0.622	4.68	0.094	0.864	3.5.4.4	167
19	0.060	1wcgA	0.601	4.63	0.063	0.846	3.2.1.147	NA
20	0.060	1k6wA	0.618	4.60	0.085	0.857	3.5.4.1	NA
21	0.060	1qw7A	0.629	4.12	0.083	0.821	3.1.8.1	NA
22	0.060	1gnxA	0.596	4.76	0.117	0.850	3.2.1.21	NA
23	0.060	3ihnA	0.624	4.04	0.096	0.804	3.5.2.3	NA
24	0.060	1gkpA	0.653	3.54	0.074	0.814	3.5.2.2	NA
25	0.060	2icsA	0.604	4.27	0.079	0.807	3.5.4.2	NA
26	0.060	1onxA	0.643	4.30	0.101	0.864	3.4.19.-	NA
27	0.060	2ftyA	0.650	4.08	0.082	0.839	3.5.2.2	166,167
28	0.060	2z26A	0.616	3.98	0.092	0.789	3.5.2.3	NA
29	0.060	1ynyB	0.652	3.73	0.082	0.821	3.5.2.2	166
30	0.060	2qt3A	0.620	4.65	0.084	0.861	3.5.99.4	130,132
31	0.060	1itqA	0.640	3.99	0.089	0.829	3.4.13.19	NA
32	0.060	1zzmA	0.604	3.67	0.092	0.768	3.1.21.-	NA
33	0.060	2ftwA	0.650	3.78	0.073	0.829	3.5.2.2	NA
34	0.060	1ybqA	0.642	4.29	0.101	0.864	3.4.19.1	NA
35	0.060	3cmjA	0.599	4.72	0.087	0.850	3.2.1.21	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.27	0.745	2.62	0.13	0.84	4i6kA	GO:0016787
1	0.27	0.636	4.22	0.09	0.85	3ij6A	GO:0016787 GO:0046872
2	0.16	0.709	3.26	0.08	0.85	4dlfA	GO:0016787
3	0.11	0.719	3.00	0.13	0.84	2ffiA	GO:0016787 GO:0047554
4	0.10	0.669	3.86	0.10	0.86	2f6kA	GO:0016787 GO:0046872
5	0.10	0.658	3.86	0.11	0.85	4qrnA	GO:0016787 GO:0046872
6	0.10	0.655	3.98	0.10	0.85	4icmA	GO:0016787 GO:0046872
7	0.10	0.661	3.92	0.08	0.86	4ofcA	GO:0001760 GO:0005829 GO:0006568 GO:0006569 GO:0008270 GO:0016787 GO:0016829 GO:0016831 GO:0046872 GO:0046874 GO:0051259 GO:0070062 GO:1904984 GO:1905004 GO:1905012
8	0.10	0.671	3.58	0.12	0.84	4mupB	GO:0016787 GO:0016853
9	0.09	0.680	3.54	0.11	0.84	4d8lA	GO:0016787 GO:0019619 GO:0047554
10	0.09	0.502	5.31	0.07	0.76	4dziC	GO:0016787
11	0.09	0.653	3.99	0.10	0.85	2gwgA	GO:0016787 GO:0046872
12	0.09	0.665	3.89	0.09	0.85	2dvtA	GO:0016787 GO:0046872
13	0.09	0.672	4.14	0.10	0.88	4qroA	GO:0016787 GO:0046872
14	0.07	0.627	4.03	0.08	0.83	3nurA	GO:0016787
15	0.07	0.604	3.67	0.09	0.77	1zzmA	GO:0004536 GO:0006308 GO:0016787 GO:0016788 GO:0016888 GO:0046872
16	0.07	0.495	4.03	0.06	0.66	3guwA	GO:0016788 GO:0046872
17	0.07	0.677	4.15	0.09	0.88	4hjwC	GO:0001760 GO:0006568 GO:0016787 GO:0046872 GO:1904984
18	0.07	0.652	4.13	0.07	0.86	4eraA	GO:0001760 GO:0006568 GO:0016787 GO:0046872 GO:1904984
19	0.07	0.533	4.85	0.05	0.77	1hizA	GO:0000272 GO:0004553 GO:0005576 GO:0005975 GO:0008152 GO:0016787 GO:0016798 GO:0031176 GO:0045493
20	0.07	0.525	5.03	0.06	0.76	2j6xH	GO:0000166 GO:0003824 GO:0010181 GO:0016491 GO:0046872 GO:0055114

Consensus prediction of GO terms

Molecular Function	GO:0016787	GO:0046872
GO-Score	0.64	0.34
Biological Processes
GO-Score
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.