Threading Zmax Znorm MUSTER 4.06 0.70 dPPAS 5.23 0.56 wdPPAS 6.12 0.66 wMUSTER 4.13 0.71 wPPAS 5.25 0.75 dPPAS2 10.05 0.96 PPAS 5.09 0.73 Env-PPAS 5.68 0.71 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.74 0.31+-0.10 14.1+-3.8 2623 0.033 model2 -4.40 1464 0.017 model3 -4.13 1818 0.022 model4 -4.65 939 0.013 model5 -5.00 619 0.007 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).