I-TASSER results

I-TASSER results for job id Rv1989c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (186 residues)
MSDALDEGLVQRIDARGTIEWSETCYRYTGAHRDALSGEGARRFGGRWNPPLLFPAIYLA
DSAQACMVEVERAAQAASTTAEKMLEAAYRLHTIDVTDLAVLDLTTPQAREAVGLENDDI
YGDDWSGCQAVGHAAWFLHMQGVLVPAAGGVGLVVTAYEQRTRPGQLQLRQSVDLTPALY
QELRAT

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MSDALDEGLVQRIDARGTIEWSETCYRYTGAHRDALSGEGARRFGGRWNPPLLFPAIYLADSAQACMVEVERAAQAASTTAEKMLEAAYRLHTIDVTDLAVLDLTTPQAREAVGLENDDIYGDDWSGCQAVGHAAWFLHMQGVLVPAAGGVGLVVTAYEQRTRPGQLQLRQSVDLTPALYQELRAT
Prediction	CCHHHCHHHHHHHHCCCCCEEEEEEEEHCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEHCCCCCEHCCCCHHHHHHHCCCHHHCCCCCHHHHHHHCCCCHHHCCCCEEEHCCCCCEEEEEHCCCCCCCCCEEEEHCCCCCCHHHHHHCCC
Conf.Score	985776899999865776455557898748887787764567777888899864346545899999999999856677767876555566666665765454479988999869997774677488888766654444344455555677568876535678877657775679985666765459
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MSDALDEGLVQRIDARGTIEWSETCYRYTGAHRDALSGEGARRFGGRWNPPLLFPAIYLADSAQACMVEVERAAQAASTTAEKMLEAAYRLHTIDVTDLAVLDLTTPQAREAVGLENDDIYGDDWSGCQAVGHAAWFLHMQGVLVPAAGGVGLVVTAYEQRTRPGQLQLRQSVDLTPALYQELRAT
Prediction	764434440053164342241322014226364521335315434442226212300211333420132034326434232542331423233340533300303346216536144541345415413643433332324323232333101003122642446414125547143541551468
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCHHHCHHHHHHHHCCCCCEEEEEEEEHCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEHCCCCCEHCCCCHHHHHHHCCCHHHCCCCCHHHHHHHCCCCHHHCCCCEEEHCCCCCEEEEEHCCCCCCCCCEEEEHCCCCCCHHHHHHCCC
MSDALDEGLVQRIDARGTIEWSETCYRYTGAHRDALSGEGARRFGGRWNPPLLFPAIYLADSAQACMVEVERAAQAASTTAEKMLEAAYRLHTIDVTDLAVLDLTTPQAREAVGLENDDIYGDDWSGCQAVGHAAWFLHMQGVLVPAAGGVGLVVTAYEQRTRPGQLQLRQSVDLTPALYQELRAT

5bvlA

0.13

0.12

0.89

0.71

MUSTER

-DKDEAWKCVEQLRRETQIAYRSDDWRDLKEAWADILIVDATDKDEAWKQEGATQIAYRSDD-WRDLKEAWKKGAD--------------ILIVDATDKDEA-WKQVEQLRREGATQIAYRSDDWRDLKEA----WKKGADILIVDATDDEAWKQVEQLRREGATQIAYRSDDWRDLKEAWKKGAD

5bvlA

0.14

0.12

0.89

0.56

dPPAS

DKDEAWKCVEQLRREGTQIAYRSDDWRDLKEAWADILIVDATDKDEAWKREGATQIAYRSDDWRDLKEAWKKGAD---------------ILIVDATDKDEA-WKQVEQLRREGATQIAYRSDDWRDLKEA----WKKGADILIVDATDDEAWKQVEQLRREGATQIAYRSDDWRDLKEAWKKGAD

4rctA2

0.09

0.08

0.84

0.68

wdPPAS

VQKIAPEQIRQLFAQTSEYHFSIPA------KTEEKSNLNVFFGEGRRDKRGF----VKPRPWYEVELIVSKDITSQEGYPVL---KSFTVITDDGWQFQCK-TSGDYSKNFRSENDLKTLG-KWIKGRLESHGCLQNNITHETLREYGNDHFELRSTDN----PDVWLLSFKGKN----------

2in3A

0.15

0.13

0.89

0.68

wMUSTER

IADP--APVIENIRQEYSAFL---TVKIPGGTNTPLLPEKHITTGQPFTFENALPFIYDTEPACRGVVSVSLIEPEKVFPFFAAIQRAFYVGQEDVAQLAIL----KKLAVDLGIPESRFAKQRTLAGFQRVAQWGISGFPALVVESGTDRYLITTGYRP---IEALR---------QLLDTWLQQ

1pjzA

0.14

0.11

0.78

0.69

wPPAS

VNKDL-QQYWSSLNVVPGA-------RV-----VPLCGKSQDMS---W-GQG-YHVVGAELS-EAAVERYFTERGEQPHITSQGDFKVYAAPGIEIWCGDFFALT----ARDIGLPADM---ERYVQHLEA---------------PQACSGLLITLEYDQALLEEVTKVGGQDTLHSSARGLKAG

4hh2A3

0.15

0.07

0.48

0.95

dPPAS2

---------------------------------------------------------------------------------------RDPMVLVSMSTGRIVDL-NSAAGLLLGGVRQDLLGAAIAQEFEGRRRGEFMETMTNLAATESAAPVEVLARRSQAAGERLLLCQIDPADA---------

4tlvA1

0.09

0.98

0.73

PPAS

PTAAIRFFGSWLREYVPEHPRRAYLYEI----RADQHFYNARATGENLLDMRQRQVVFDSGDREMAQMGIRALRTSFAGPIAAANVRSAWLVDAVPVEPGHAHHPAGRVVETTRINEPEMHNPHYQELQTQANDQPWLPTPGIATPVLSIPQAASVADVSEGTSASLSFACPDWSPPNPLDKCIAE

3hzhB

0.07

0.05

0.78

0.71

Env-PPAS

YIEPFLDAASSVLRDLLVENIEGKPGLKSIKGVSVIVG-----LAGSVE--GS--IIIDD--IETALFVASKLNFEEYDDFDDE------------ETKEVAATLTEVGNIIAGNFVTTLHAKGF--VFDITPPAFIYGENKIS--NKGSEALIVPFSLPDGKIIEVNIAIRE-------------

4kl0A2

0.11

0.10

0.90

0.66

MUSTER

LTPTEAAVLRELRLHRPQLPLDTLLFTDPNKDPDDVVTYTIAKQLQADGFLRLTDVVVTLGDADMRSQRAQLAKGVFDRLALPDVRVARGQDYPMTSTQAREHSKFLAEGAALRAAPDAVHTDGVRAMCER----LATSPHK----------LGMVVIAGMTDASAL-----LAEAGDLVREKVAS

5bq5A

0.07

0.06

0.88

0.56

dPPAS

AQPSVDERRIRELLTLSFIDRKENILFLGPPG----IGKTHLAISIGEAIARGYKTYFITAHDLVNQLRRADQEGKLEKKLRVFVKPTVLIIDEGYLKLDPNSAHYLFQVIARRYEHAPIINKSFGEWGEIVGDSVLATALDRLL----HHSIIFNLKGESYRLREKRLQEE--------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.74

Estimated TM-score = 0.31±0.10

Estimated RMSD = 14.1±3.8Å

Download Model 2

C-score=-4.40

Download Model 3

C-score=-4.13

Download Model 4

C-score=-4.65

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5bvlA	0.766	2.26	0.115	0.887
2	3bofA	0.702	3.52	0.079	0.957
3	4r27A	0.699	3.42	0.097	0.941
4	1qw9A	0.696	3.81	0.050	0.968
5	3noyA1	0.694	3.60	0.079	0.946
6	2y0fA1	0.694	3.46	0.091	0.935
7	2c8nA	0.693	3.82	0.067	0.968
8	3ahxA	0.693	3.79	0.105	0.968
9	2y2wA	0.693	3.79	0.078	0.968
10	1wcgA	0.693	3.77	0.061	0.968

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.11	7	3s1wA	GOL	Rep, Mult	22,38,39,40,119,144,146,168,170
2	0.09	6	2fliA	ZN	Rep, Mult	38,40,58,170
3	0.05	3	1bosC	UUU	Rep, Mult	47,48,49
4	0.05	3	2z5xA	DCX	Rep, Mult	52,53,55,58
5	0.05	3	3a4xA	UUU	Rep, Mult	23,58,60,95,104,120,122,123,146,170
6	0.03	2	2fmoA	FAD	Rep, Mult	22,23,25,38,59,60,66,67,93,106,110,120,121,122,170
7	0.03	2	1iwpA	PGO	Rep, Mult	38,57,119,120,168
8	0.03	2	3s1uB	E4P	Rep, Mult	22,40,93,146,148,170,171,173
9	0.02	1	2o01J	CLA	Rep, Mult	69,72
10	0.02	1	1vh8B	UUU	Rep, Mult	40,44,47
11	0.02	1	2z5yA	DCX	Rep, Mult	48,55,58,59
12	0.02	1	2o66A	FLC	Rep, Mult	27,33

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.193	1tqxA	0.660	3.54	0.054	0.903	5.1.3.1	NA
2	0.105	1xi3A	0.633	3.34	0.069	0.855	2.5.1.3	NA
3	0.079	3exrA	0.664	3.55	0.082	0.919	4.1.1.85	61,63,68
4	0.077	3f4wA	0.664	3.44	0.065	0.909	4.1.2.-	24,41
5	0.070	1xbzB	0.668	3.38	0.089	0.903	4.1.1.85	61,65
6	0.070	1xi3B	0.633	3.34	0.069	0.855	2.5.1.3	40,122,148
7	0.069	2yw3E	0.630	3.42	0.125	0.860	4.1.2.14	39
8	0.068	1h1yA	0.648	3.64	0.078	0.892	5.1.3.1	92
9	0.067	2yswA	0.644	3.91	0.075	0.925	4.2.1.10	NA
10	0.067	1h1yB	0.648	3.66	0.071	0.903	5.1.3.1	NA
11	0.067	1j2wA	0.633	3.53	0.081	0.866	4.1.2.4	NA
12	0.067	2yswC	0.641	3.94	0.076	0.919	4.2.1.10	NA
13	0.067	2cz5A	0.642	3.65	0.036	0.892	4.1.1.23	61
14	0.067	2v81A	0.632	3.43	0.088	0.855	4.1.2.21	NA
15	0.067	1vqtA	0.593	3.93	0.044	0.855	4.1.1.23	NA
16	0.067	2czfA	0.631	3.81	0.036	0.903	4.1.1.23	3,120,146
17	0.067	1v5xA	0.613	3.62	0.100	0.850	5.3.1.24	95
18	0.067	2ox1D	0.597	4.12	0.036	0.876	4.2.1.10	NA
19	0.066	1hg3A	0.665	3.28	0.067	0.882	5.3.1.1	NA
20	0.066	2h6rB	0.638	3.57	0.067	0.876	5.3.1.1	111
21	0.060	2cksB	0.678	3.78	0.089	0.962	3.2.1.4	NA
22	0.060	1bqcA	0.676	3.70	0.063	0.935	3.2.1.78	NA
23	0.060	1dwaM	0.681	3.71	0.072	0.957	3.2.1.147	NA
24	0.060	3aboA	0.685	3.65	0.039	0.957	4.3.1.7	121,169
25	0.060	1dioA	0.680	3.73	0.080	0.946	4.2.1.28	NA
26	0.060	2gftB	0.674	4.17	0.066	0.979	3.2.1.89	NA
27	0.060	2pbgA	0.678	3.95	0.056	0.962	3.2.1.85	NA
28	0.060	1ybqA	0.676	3.90	0.045	0.962	3.4.19.1	61
29	0.060	2j62A	0.677	4.05	0.022	0.973	3.2.1.52	NA
30	0.060	1qoxM	0.687	3.89	0.072	0.973	3.2.1.21	25
31	0.060	1tvnA	0.674	3.71	0.051	0.946	3.2.1.4	NA
32	0.060	2jf6B	0.678	3.87	0.050	0.968	3.2.1.105	20
33	0.060	2c8nA	0.693	3.82	0.067	0.968	3.2.1.55	56
34	0.060	1v03A	0.689	3.62	0.067	0.957	3.2.1.21	NA
35	0.060	1nvmA	0.687	3.70	0.063	0.946	4.1.3.38	NA
36	0.060	1onxA	0.677	3.89	0.045	0.962	3.4.19.-	NA
37	0.060	1myrA	0.683	3.68	0.072	0.957	3.2.1.147	111
38	0.060	1kwgA	0.676	3.49	0.052	0.919	3.2.1.23	NA
39	0.060	1eokA	0.673	3.98	0.085	0.941	3.2.1.96	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.29	0.670	3.65	0.07	0.91	1dvjA	GO:0003824 GO:0004590 GO:0006207 GO:0006221 GO:0008152 GO:0016829 GO:0016831 GO:0044205
1	0.12	0.629	3.45	0.05	0.84	1lt7B	GO:0000096 GO:0005737 GO:0005829 GO:0006479 GO:0006577 GO:0006579 GO:0008168 GO:0008270 GO:0008898 GO:0009086 GO:0016740 GO:0032259 GO:0042426 GO:0046500 GO:0046872 GO:0047150 GO:0050666 GO:0070062 GO:0071267
2	0.12	0.678	3.59	0.08	0.94	5dmlA	GO:0006974 GO:0008168 GO:0008652 GO:0008898 GO:0009086 GO:0016740 GO:0032259 GO:0033477 GO:0046872
3	0.11	0.676	3.30	0.08	0.89	5dmnA	GO:0006974 GO:0008168 GO:0008652 GO:0008898 GO:0009086 GO:0016740 GO:0032259 GO:0033477 GO:0046872
4	0.11	0.677	3.59	0.09	0.92	4djdA	GO:0005509 GO:0008168 GO:0015977 GO:0016740 GO:0031419 GO:0032259 GO:0042558 GO:0044237 GO:0046872 GO:0102036
5	0.11	0.581	3.83	0.03	0.84	1umyD	GO:0005737 GO:0005829 GO:0006479 GO:0006579 GO:0008168 GO:0008270 GO:0008898 GO:0009086 GO:0010243 GO:0016740 GO:0032259 GO:0032403 GO:0043234 GO:0046872 GO:0047150
6	0.10	0.659	3.59	0.09	0.90	4cczA	GO:0000096 GO:0005622 GO:0005737 GO:0005829 GO:0007399 GO:0008168 GO:0008270 GO:0008652 GO:0008705 GO:0008898 GO:0009086 GO:0009235 GO:0016740 GO:0031103 GO:0031419 GO:0032259 GO:0042558 GO:0044237 GO:0046872 GO:0048678 GO:0071732
7	0.10	0.699	3.54	0.07	0.96	1q7qA	GO:0008168 GO:0008705 GO:0009086 GO:0016740 GO:0031419 GO:0032259 GO:0042558 GO:0044237 GO:0046872
8	0.09	0.590	3.12	0.06	0.75	3k13C	GO:0005829 GO:0008168 GO:0008270 GO:0008705 GO:0008898 GO:0009086 GO:0016740 GO:0031419 GO:0032259 GO:0042558 GO:0044237 GO:0046872
9	0.09	0.605	3.63	0.11	0.82	4o0qA	GO:0042558 GO:0044237
10	0.08	0.676	3.61	0.07	0.92	2yckX	GO:0006760 GO:0008168 GO:0016740 GO:0032259 GO:0042558 GO:0044237
11	0.07	0.455	5.18	0.08	0.77	4jjpA	GO:0000166 GO:0005524 GO:0008972 GO:0009228 GO:0016301 GO:0016310 GO:0016740
12	0.07	0.424	5.27	0.06	0.73	1ecfB	GO:0000287 GO:0004044 GO:0005737 GO:0005829 GO:0006164 GO:0006189 GO:0006541 GO:0009113 GO:0009116 GO:0016740 GO:0016757 GO:0042802 GO:0046872
13	0.06	0.422	4.92	0.05	0.69	1vjoA	GO:0003824 GO:0008483 GO:0016740
14	0.06	0.396	4.98	0.05	0.63	3ifsE	GO:0004347 GO:0005737 GO:0006094 GO:0006096 GO:0016853
15	0.06	0.391	5.45	0.05	0.70	3lhiA	GO:0005975 GO:0006098 GO:0017057
16	0.06	0.399	5.37	0.05	0.68	3ju7A	GO:0003824
17	0.06	0.348	5.71	0.06	0.65	5ez7A	GO:0016491 GO:0055114
18	0.06	0.363	5.61	0.07	0.63	4zrhF	GO:0001922 GO:0002020 GO:0002237 GO:0002634 GO:0002677 GO:0003677 GO:0003824 GO:0004842 GO:0004843 GO:0005634 GO:0005737 GO:0005764 GO:0005829 GO:0006508 GO:0006915 GO:0006954 GO:0008152 GO:0008233 GO:0008234 GO:0008270 GO:0010803 GO:0016567 GO:0016579 GO:0016787 GO:0016874 GO:0019900 GO:0031397 GO:0032088 GO:0032480 GO:0032495 GO:0032691 GO:0032703 GO:0032715 GO:0032720 GO:0034136 GO:0034140 GO:0034144 GO:0034148 GO:0035871 GO:0036459 GO:0043124 GO:0043130 GO:0043621 GO:0045732 GO:0045736 GO:0045779 GO:0045824 GO:0046872 GO:0048662 GO:0050691 GO:0050727 GO:0050728 GO:0050869 GO:0051259 GO:0060548 GO:0061043 GO:0070062 GO:0070301 GO:0070423 GO:0070429 GO:0070433 GO:0070530 GO:0070536 GO:0070936 GO:0071108 GO:0071222 GO:0071947 GO:0072573 GO:0072666 GO:0090291 GO:1902042 GO:1903364 GO:2000347 GO:2000349 GO:2000352

Consensus prediction of GO terms

Molecular Function	GO:0016830	GO:0046872	GO:0008898
GO-Score	0.59	0.39	0.31
Biological Processes	GO:0006222	GO:0019856	GO:0033554	GO:0006790	GO:0032259	GO:0009086
GO-Score	0.59	0.59	0.43	0.43	0.39	0.31
Cellular Component	GO:0005829	GO:0070062
GO-Score	0.12	0.12

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.