Threading Zmax Znorm MUSTER 3.54 0.61 dPPAS 7.06 0.76 wdPPAS 7.11 0.76 wMUSTER 4.24 0.73 wPPAS 5.39 0.77 dPPAS2 13.37 1.27 PPAS 5.46 0.78 Env-PPAS 7.68 0.96 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.22 0.56+-0.15 7.1+-4.2 9412 0.357 model2 -3.38 1409 0.041 model3 -2.89 727 0.067 model4 -4.14 605 0.019 model5 -3.76 811 0.028 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).