I-TASSER results

Input Sequence in FASTA format

>protein (135 residues)
MRWIVDGMNVIGSRPDGWWRDRHRAMVMLVERLEGWAITKARGDDVTVVFERPPSTAIPS
SVVEVAHAPKAAANSADDEIVRLVRSGAQPQEIRVVTSDKALTDRVRDLGAAVYPAERFR
DLIDPRGSNAARRTQ

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MRWIVDGMNVIGSRPDGWWRDRHRAMVMLVERLEGWAITKARGDDVTVVFERPPSTAIPSSVVEVAHAPKAAANSADDEIVRLVRSGAQPQEIRVVTSDKALTDRVRDLGAAVYPAERFRDLIDPRGSNAARRTQ
Prediction	CEEEEEHCEEHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHCCCCCCCCCCCCCEEEEEHCCCCCCHHHHHHHHHHHCCCCCCEEEEHCCHHHHHHHHHHCCEEHCHHHHHHHHHHHHHHHHHHHC
Conf.Score	979999643445677775455899999999999998765788868999975888877556775799986578887589999999977789858999788999999999898887899999999988877777659
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 \| \| \| \| \| \| MRWIVDGMNVIGSRPDGWWRDRHRAMVMLVERLEGWAITKARGDDVTVVFERPPSTAIPSSVVEVAHAPKAAANSADDEIVRLVRSGAQPQEIRVVTSDKALTDRVRDLGAAVYPAERFRDLIDPRGSNAARRTQ
Prediction	430201021030023422144153035302640462356626314000001134443454753423423443644103201410454456430000011441253047240412315301520463476445568
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120

                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CEEEEEHCEEHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHCCCCCCCCCCCCCEEEEEHCCCCCCHHHHHHHHHHHCCCCCCEEEEHCCHHHHHHHHHHCCEEHCHHHHHHHHHHHHHHHHHHHC
MRWIVDGMNVIGSRPDGWWRDRHRAMVMLVERLEGWAITKARGDDVTVVFERPPSTAIPSSVVEVAHAPKAAANSADDEIVRLVRSGAQPQEIRVVTSDKALTDRVRDLGAAVYPAERFRDLIDPRGSNAARRTQ

2mr6A

0.12

0.08

0.66

1.28

dPPAS2

------------------------------------------MGVVILVLTGDERKEVQKHDPNVKTVPTKDKEKVKEEIEKARKQGRP--IVVFVRGGKDIAEYAQKEGLRVI--VIIVSQDEEALRKGYEDKK

3fwzA2

0.14

0.07

0.47

1.26

dPPAS2

------------------------------------------------------------------LILTIPNGYEAGEIVASARAKNPDIEIIARAHYDDEVAYITERGAQVVGEREIARTLELLETP------

1qo0E

0.15

0.13

0.81

0.60

MUSTER

QVLVLN--------PG-------EVSDALVLQLIRIG------CSVRQCWPPPEAFDVPVD----VVFTSIFQNRHHDEIAALLAAGTPRTTLVALVESPAVLSQIIELECVITDAHRVLPVLVSARRISEEMAK

2mr6A

0.08

0.07

0.87

0.76

dPPAS

VVILVLTGD-----------------ERIAEELRKEVQKHDPNVKTVPTKDKEEIEKARKQGRPIVVFVRGGDDERAKDIAEYAQKEGLRVIVIIVSQDRKGYEDKKKKGYDVYTSRNEDEAKKKLKEALEKSGS

2qv0A

0.14

0.12

0.83

0.79

wdPPAS

MVIIVE--------------DEFLAQQELSWLINTHS-----QMEIVGSFDDGLDVLKFLQHNKVDAIFLNIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEA--YQESRIINMLQKLTTAWEQQ--

2v0nA

0.10

0.08

0.84

0.70

wMUSTER

RILVVD--------------DIEANVRLLEAKLTAEY------YEVSTAMDGPTLAMAARDLPDIILLVMMPGMDGFTVCRKLKDDPTTRHPVVLITAGRGDRIQGLESGA--IDDVMLFARVRSLTRFKLVIDE

2qv0A

0.16

0.12

0.76

0.72

wPPAS

MVIIVE--------------DEFLAQQELSWLINTHS-----QMEIVGSFDGL-------QHNKVDAIF---PSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEA--YQESRIINMLQKLTTAWEQQ--

1qo0E

0.15

0.13

0.82

1.21

dPPAS2

QVLVLNP-------PG-------EVSDALVLQLIRIG------CSVRQCWPPPEAFDVPVD----VVFTSIFQNRHHDEIAALLAAGTPRTTLVALVESPAVLSQIIELECQPLDAHRVLPVLVSARRISEEMAK

2mr6A

0.06

0.05

0.87

0.79

PPAS

VVILVLTGD-----------------ERIAEELRKEVQKHDPNVKTVPTKDKEEIEKARKQGRPIVVFVRGGDDERAKDIAEYAQKEGLRVIVIIVSQDRKGYEDKKKKGYTSRNEDEAKKKLKEALEKSGSLEH

3zd8A2

0.15

0.14

0.96

Env-PPAS

VLLIVDALNLIRRI---HAVQGSPCVETCQHALDQLIMH-SQPTHAVAVFDGWRHQRLPDALRAAFEQRGVPCWSADDLAATLAVKVTAGHQATIVSTDKGYCQLL-SPTLRIRDYKRWLLQTDLHIDGNLQQLR

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.22

Estimated TM-score = 0.56±0.15

Estimated RMSD = 7.1±4.2Å

Download Model 2

C-score=-3.38

Download Model 3

C-score=-2.89

Download Model 4

C-score=-4.14

Download Model 5

C-score=-3.76

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4cbvA1	0.708	2.65	0.116	0.889
2	2rjnA	0.705	2.25	0.096	0.852
3	2qv0A	0.701	2.26	0.106	0.837
4	3jteA	0.694	2.32	0.088	0.844
5	3a9rA	0.694	3.02	0.078	0.911
6	3n0wA1	0.694	2.57	0.068	0.874
7	3cu5B	0.691	2.42	0.069	0.859
8	3cfyA	0.689	2.38	0.105	0.844
9	3hv2A	0.689	2.41	0.078	0.852
10	2e4zA2	0.689	3.18	0.061	0.918

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.18	7	1dckB	MN	Rep, Mult	6,22,70,72
2	0.10	4	2wksA	CB6	Rep, Mult	68,70,78,95,96,97
3	0.09	3	1zdmA	XE	Rep, Mult	5,6,29,68,69,70,96
4	0.05	2	3zt9A	MN	Rep, Mult	6,7,11,12
5	0.03	1	1ny6H	ADP	Rep, Mult	29,30,31,32
6	0.03	1	2c4v0	III	Rep, Mult	36,93,99,101,111,112,113,114,115,124,125,128
7	0.03	1	3m9gA	ZN	Rep, Mult	99,110

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.212	1bdjA	0.606	3.30	0.103	0.859	2.7.13.3	77,79,111
2	0.128	2kyrA	0.488	3.47	0.080	0.689	2.7.1.69	28,34
3	0.097	1uqrK	0.635	3.27	0.092	0.911	4.2.1.10	72,98
4	0.094	1y80A	0.638	2.50	0.073	0.800	2.1.1.13	NA
5	0.083	2uygA	0.632	3.25	0.072	0.881	4.2.1.10	14,92
6	0.083	2r25B	0.665	2.62	0.070	0.822	2.7.13.3	NA
7	0.083	2uygL	0.631	3.26	0.072	0.881	4.2.1.10	72
8	0.068	1iibA	0.504	3.62	0.079	0.748	2.7.1.69	69,71
9	0.067	1h0rA	0.623	3.37	0.090	0.881	4.2.1.10	92
10	0.067	1gqoB	0.629	3.29	0.119	0.889	4.2.1.10	14,92
11	0.067	1d0iH	0.644	3.27	0.116	0.911	4.2.1.10	14,92
12	0.067	3lwzA	0.635	3.43	0.101	0.911	4.2.1.10	72
13	0.067	1uqrD	0.639	3.34	0.084	0.918	4.2.1.10	14
14	0.067	1b1aA	0.576	3.31	0.081	0.822	5.4.99.1	NA
15	0.067	1be1A	0.571	3.40	0.071	0.830	5.4.99.1	NA
16	0.066	2fewB	0.511	2.65	0.088	0.659	2.7.1.69	25,32,47
17	0.066	1tvmA	0.520	2.79	0.077	0.659	2.7.1.69	31
18	0.060	3bicB	0.654	2.85	0.085	0.859	5.4.99.2	23
19	0.060	3do6A	0.653	3.02	0.100	0.867	6.3.4.3	NA
20	0.060	3esbA	0.524	4.03	0.058	0.837	3.1.1.74	NA
21	0.060	3bc1A	0.643	3.06	0.059	0.881	3.6.5.2	NA
22	0.060	2i2xB	0.649	2.73	0.085	0.830	2.1.1.90	NA
23	0.060	1e1cA	0.648	2.77	0.095	0.844	5.4.99.2	NA
24	0.060	2vycA	0.658	3.12	0.089	0.911	4.1.1.19	NA
25	0.060	2q0sH	0.632	3.75	0.111	0.933	3.1.1.2	74
26	0.060	2vg8A	0.672	2.57	0.105	0.844	2.4.1.218	NA
27	0.060	1reqA	0.646	2.77	0.095	0.844	5.4.99.2	51
28	0.060	3mwdB	0.667	2.55	0.088	0.844	2.3.3.8	NA
29	0.060	1t34A	0.658	3.23	0.050	0.896	4.6.1.2	NA
30	0.060	2c4wA	0.679	3.15	0.083	0.926	4.2.1.10	NA
31	0.060	1t0iA	0.638	3.01	0.103	0.859	1.5.1.29	78
32	0.060	2bd0A	0.666	2.35	0.068	0.830	1.1.1.153	NA
33	0.060	1cb7A	0.639	2.70	0.088	0.822	5.4.99.1	NA
34	0.060	2v0nA	0.666	2.53	0.114	0.844	2.7.7.65	NA
35	0.060	2elfA	0.638	3.09	0.060	0.867	3.6.1.48	100
36	0.060	1auoA	0.645	2.74	0.062	0.837	3.1.1.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.30	0.701	2.26	0.11	0.84	2qv0A	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
1	0.27	0.621	2.78	0.12	0.84	1nxpA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355 GO:0046872
2	0.27	0.653	2.30	0.10	0.81	2qxyA	GO:0000160 GO:0005622
3	0.26	0.694	2.32	0.09	0.84	3jteA	GO:0000160 GO:0003824 GO:0005622
4	0.26	0.653	2.82	0.10	0.84	3hebA	GO:0000160 GO:0005622
5	0.25	0.610	2.90	0.14	0.83	3f6pA	GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355
6	0.24	0.664	2.61	0.14	0.84	3kcnB	GO:0000160 GO:0005622
7	0.24	0.622	3.02	0.08	0.85	3gt7A	GO:0000155 GO:0000160 GO:0005622 GO:0007165 GO:0016301 GO:0016310 GO:0016772 GO:0023014
8	0.22	0.666	2.46	0.12	0.82	1zgzA	GO:0000156 GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355
9	0.22	0.580	3.44	0.05	0.84	4hnqA	GO:0000160 GO:0005622 GO:0046872
10	0.21	0.598	3.04	0.09	0.82	3i42A	GO:0000160 GO:0005622
11	0.21	0.637	2.58	0.09	0.81	3eqzB	GO:0000156 GO:0000160 GO:0005622
12	0.21	0.668	2.34	0.13	0.82	4uhkA	GO:0000160 GO:0003677 GO:0003700 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0010810 GO:0045892 GO:0045893
13	0.21	0.653	2.36	0.09	0.79	3a0rB	GO:0000160 GO:0005622 GO:0046872
14	0.20	0.626	2.87	0.13	0.81	1p6qA	GO:0000160 GO:0005622
15	0.20	0.621	2.75	0.10	0.82	4nicA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
16	0.20	0.610	2.92	0.15	0.82	3lteD	GO:0000160 GO:0003677 GO:0005622
17	0.20	0.627	2.98	0.10	0.85	1l5yB	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005737 GO:0006351 GO:0006355 GO:0008134 GO:0043565
18	0.19	0.688	2.39	0.12	0.84	2jk1A	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005737 GO:0006351 GO:0006355 GO:0008134 GO:0043565
19	0.19	0.611	2.95	0.11	0.83	3hdvB	GO:0000160 GO:0005622
20	0.19	0.613	2.76	0.09	0.81	2qr3A	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0008134 GO:0043565
21	0.19	0.605	3.35	0.10	0.86	3rvrB	GO:0000160 GO:0000287 GO:0005737 GO:0005829 GO:0006473 GO:0006935 GO:0016407 GO:0018393 GO:0046872 GO:0071973 GO:0097588
22	0.18	0.650	2.76	0.09	0.85	3khtA	GO:0000160 GO:0003677 GO:0005622
23	0.17	0.614	3.02	0.12	0.84	5e3jA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
24	0.16	0.652	2.50	0.08	0.81	3luaA	GO:0000160 GO:0005622
25	0.16	0.661	2.23	0.09	0.80	1tmyA	GO:0000160 GO:0005737 GO:0006935 GO:0046872 GO:0097588
26	0.16	0.665	2.62	0.07	0.82	2r25B	GO:0000155 GO:0000156 GO:0000160 GO:0000166 GO:0004673 GO:0005034 GO:0005524 GO:0005622 GO:0005886 GO:0005887 GO:0006469 GO:0007165 GO:0007234 GO:0009927 GO:0016020 GO:0016021 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0018106 GO:0023014 GO:0046777 GO:0046872
27	0.16	0.659	2.53	0.11	0.83	2pl1A	GO:0000160 GO:0003677 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0042802
28	0.16	0.638	2.80	0.15	0.85	1xheB	GO:0000156 GO:0000160 GO:0003677 GO:0003700 GO:0005737 GO:0005829 GO:0006351 GO:0006355 GO:0042802 GO:0045892 GO:0045893
29	0.15	0.653	2.85	0.17	0.84	5ic5A	GO:0000160 GO:0005622
30	0.15	0.691	2.42	0.07	0.86	3cu5B	GO:0000160 GO:0003677 GO:0003700 GO:0005622 GO:0006351 GO:0006355 GO:0043565
31	0.15	0.705	2.25	0.10	0.85	2rjnA	GO:0000160 GO:0005622 GO:0016787
32	0.13	0.614	2.95	0.12	0.83	3t6kA	GO:0000160 GO:0005622
33	0.12	0.687	2.74	0.12	0.90	4cbvF	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
34	0.12	0.620	2.94	0.10	0.84	1m5tA	GO:0000160 GO:0005622 GO:0046872
35	0.11	0.686	2.33	0.15	0.84	1dbwB	GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0009399 GO:0046872
36	0.11	0.689	2.41	0.08	0.85	3hv2A	GO:0000156 GO:0000160 GO:0005622
37	0.11	0.607	2.26	0.13	0.73	1mb0A	GO:0000160 GO:0005622 GO:0046872
38	0.10	0.619	2.96	0.08	0.84	4d6yA	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0008134 GO:0043565
39	0.10	0.689	2.38	0.10	0.84	3cfyA	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0008134 GO:0043565
40	0.10	0.608	2.90	0.06	0.82	3dgeC	GO:0000160 GO:0005622 GO:0046872
41	0.10	0.618	2.84	0.08	0.83	3b2nA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
42	0.09	0.619	3.08	0.13	0.85	3f7aB	GO:0000160 GO:0003824 GO:0005622 GO:0046872
43	0.09	0.669	2.55	0.10	0.85	2ayxA	GO:0000155 GO:0000160 GO:0000166 GO:0004673 GO:0004871 GO:0005524 GO:0005622 GO:0005886 GO:0005887 GO:0006355 GO:0007165 GO:0016020 GO:0016021 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0018106 GO:0023014 GO:0044010 GO:0046777 GO:0071470
44	0.09	0.660	2.62	0.10	0.84	3hdgA	GO:0000155 GO:0000160 GO:0005622 GO:0007165 GO:0023014 GO:0046872
45	0.09	0.629	2.80	0.12	0.83	1dc7A	GO:0000156 GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0006808 GO:0008134 GO:0009399 GO:0043565
46	0.09	0.621	2.59	0.14	0.79	3m6mD	GO:0000155 GO:0000160 GO:0000166 GO:0004673 GO:0004871 GO:0005524 GO:0005622 GO:0005886 GO:0006351 GO:0006355 GO:0007165 GO:0009405 GO:0016020 GO:0016021 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0018106 GO:0023014
47	0.09	0.671	2.63	0.13	0.85	1yioA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355 GO:0046872
48	0.09	0.556	2.71	0.09	0.72	4qwvA	GO:0000160 GO:0005737 GO:0006865 GO:0006935 GO:0046872 GO:0097588
49	0.09	0.672	2.63	0.11	0.84	3dzdA	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005622 GO:0006351 GO:0006355 GO:0008134 GO:0043565
50	0.08	0.607	3.15	0.10	0.84	3eulB	GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355
51	0.08	0.585	3.38	0.12	0.84	3cg4A	GO:0000160 GO:0005622 GO:0046872
52	0.08	0.650	2.87	0.12	0.86	4zylB	GO:0000160 GO:0005622
53	0.08	0.662	2.73	0.13	0.84	4q7eA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
54	0.07	0.649	2.51	0.06	0.81	3hzhA	GO:0000160 GO:0005622 GO:0046872
55	0.07	0.645	2.67	0.05	0.83	2qvgA	GO:0000160 GO:0005622 GO:0016740
56	0.07	0.629	2.65	0.08	0.80	3kyjB	GO:0000160 GO:0005622
57	0.07	0.649	2.73	0.12	0.82	3t8yB	GO:0000156 GO:0000160 GO:0004871 GO:0005737 GO:0006935 GO:0007165 GO:0008984 GO:0016787
58	0.07	0.648	2.46	0.08	0.80	4eukA	GO:0000155 GO:0000160 GO:0004673 GO:0005737 GO:0005773 GO:0005886 GO:0006952 GO:0007165 GO:0007275 GO:0009736 GO:0009738 GO:0009788 GO:0009873 GO:0010105 GO:0016020 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0018106 GO:0023014 GO:0046872 GO:0048364 GO:0070301 GO:0071219 GO:0071732 GO:0090333
59	0.07	0.610	2.84	0.11	0.81	2jviA	GO:0000160 GO:0005737 GO:0016301 GO:0016310 GO:0016740 GO:0030435 GO:0046872
60	0.07	0.624	2.56	0.10	0.79	5dclA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
61	0.07	0.589	3.11	0.08	0.81	1mvoA	GO:0000160 GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0006810 GO:0006817
62	0.07	0.658	2.64	0.07	0.84	1i3cA	GO:0000160 GO:0005622
63	0.07	0.568	2.35	0.12	0.70	3q15D	GO:0000160 GO:0005737 GO:0016301 GO:0016310 GO:0016740 GO:0030435 GO:0046872
64	0.07	0.621	2.73	0.08	0.82	2hqrA	GO:0000160 GO:0003677 GO:0005622 GO:0006351 GO:0006355
65	0.07	0.596	3.16	0.09	0.81	1s8nA	GO:0000160 GO:0003723 GO:0005618 GO:0005622 GO:0005886 GO:0006351 GO:0006355 GO:0031564 GO:0040007
66	0.07	0.637	2.97	0.09	0.87	1a04A	GO:0000160 GO:0000166 GO:0003677 GO:0005524 GO:0005829 GO:0006351 GO:0006355 GO:0010468 GO:0042128 GO:0090352

Consensus prediction of GO terms

Molecular Function	GO:0043169	GO:0003677
GO-Score	0.55	0.49
Biological Processes	GO:0000160	GO:0006355
GO-Score	0.79	0.49
Cellular Component	GO:0005622
GO-Score	0.79

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv1976c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]