Threading Zmax Znorm MUSTER 4.40 0.76 dPPAS 9.08 0.98 wdPPAS 7.76 0.83 wMUSTER 4.18 0.72 wPPAS 5.92 0.85 dPPAS2 12.42 1.18 PPAS 5.65 0.81 Env-PPAS 6.95 0.87 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11034) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.03 0.37+-0.13 11.4+-4.5 3397 0.055 model2 -2.90 2201 0.063 model3 -4.40 813 0.014 model4 -3.68 757 0.029 model5 -3.32 2073 0.041 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).