Threading Zmax Znorm MUSTER 5.59 0.96 dPPAS 7.89 0.85 wdPPAS 16.07 1.73 wMUSTER 6.34 1.09 wPPAS 16.66 2.38 dPPAS2 19.69 1.87 PPAS 10.86 1.55 Env-PPAS 15.32 1.91 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.22 0.35+-0.12 12.8+-4.2 3264 0.026 model2 -3.34 2656 0.023 model3 -3.73 1946 0.016 model4 -3.41 1603 0.021 model5 -3.74 1900 0.015 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).