I-TASSER results

I-TASSER results for job id Rv1918c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (987 residues)
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGR
SSVAMAAAAAPYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISL
VISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAA
GPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSG
NFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNG
LTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTG
FLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTG
AFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAI
TLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIP
ATTTPANITVGAFNLPQLSIPSVTVPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGT
TVGGFTLPTIHTPLISTPQISIGGFSTPGIATQANSGVINLPTFSLNGITITNLVVFIPN
NITALQTNMPGVFPQIGGFANTPPAFINTGTITVGGGQINGVGFSIGAINVTPFTLPNVV
IQPWSLGGISVDGFTLPEISTQEFTTPALTISPIGVGALSLPDITTQQFTTPELTIDPIT
LGGFTLPQLSIPAITTPAFTIDPIALGGFTLPQIMTPEITTPPFAIDPIGLSGFTLPQVN
IPEITTPEFTIQPVGLAAFTTPALTIASIHLPSTTMGGFAIPAGPGYFNSSATPSLGFFN
AGIGGNSGFGNSGSGLSGWFNTSPVGLLAGSGYQNYGGLISGFSNLGSGISGFANTGTLP
FAVTSLVSGLANIGNNLSGLFFQSTTP

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSGNFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTGAFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAITLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSIPSVTVPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGTTVGGFTLPTIHTPLISTPQISIGGFSTPGIATQANSGVINLPTFSLNGITITNLVVFIPNNITALQTNMPGVFPQIGGFANTPPAFINTGTITVGGGQINGVGFSIGAINVTPFTLPNVVIQPWSLGGISVDGFTLPEISTQEFTTPALTISPIGVGALSLPDITTQQFTTPELTIDPITLGGFTLPQLSIPAITTPAFTIDPIALGGFTLPQIMTPEITTPPFAIDPIGLSGFTLPQVNIPEITTPEFTIQPVGLAAFTTPALTIASIHLPSTTMGGFAIPAGPGYFNSSATPSLGFFNAGIGGNSGFGNSGSGLSGWFNTSPVGLLAGSGYQNYGGLISGFSNLGSGISGFANTGTLPFAVTSLVSGLANIGNNLSGLFFQSTTP
Prediction	CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score	986668865666545688996899999999999999999999999999988655667886899999999889999999999999999999999999999988678855677788999999866888876466655556665566666776656678888776778888888888888888877778888888888888888888888888888888888888888888888888888888899888988889988888889999999988899899998899988888888999999889999899999999999999998999999998899999999999999899888999999999899999999889999899988999999998889999999889999999988889988899899999999988999888888888888888888888888889988899888888888888899888988889988889998899888898888888889888888888898888988889888998888898889998899988998889988889888899888998888988899988899888998889988899888999899988899999988899998998888999888899888998899988898888988999889999888999999999899998888988899988899899988899999998889999999888999999988899999998888988899888998889988898888998889988899888998889988899888899888988899888898889988889888888889988899888998888888889888888888899888888999998888888899888888899888888888888888888778888888888888888888888887767888887766899999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 360 380 400 420 440 460 480 500 520 540 560 580 600 620 640 660 680 700 720 740 760 780 800 820 840 860 880 900 920 940 960 980 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSGNFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTGAFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAITLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSIPSVTVPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGTTVGGFTLPTIHTPLISTPQISIGGFSTPGIATQANSGVINLPTFSLNGITITNLVVFIPNNITALQTNMPGVFPQIGGFANTPPAFINTGTITVGGGQINGVGFSIGAINVTPFTLPNVVIQPWSLGGISVDGFTLPEISTQEFTTPALTISPIGVGALSLPDITTQQFTTPELTIDPITLGGFTLPQLSIPAITTPAFTIDPIALGGFTLPQIMTPEITTPPFAIDPIGLSGFTLPQVNIPEITTPEFTIQPVGLAAFTTPALTIASIHLPSTTMGGFAIPAGPGYFNSSATPSLGFFNAGIGGNSGFGNSGSGLSGWFNTSPVGLLAGSGYQNYGGLISGFSNLGSGISGFANTGTLPFAVTSLVSGLANIGNNLSGLFFQSTTP
Prediction	421001000100010100000000100010010003002200300100000000111100000000000100100001002103300320210000011011121221202111210010001112122111002011425424234210121123112122222222233232323322222222322112122222222222222111111111102121112111321112222432221121101211122111211101111021211120102111113123221113332143111421113132121321213211143121201112211122132431203112143121221213312132331431313211122010222212313221121333112121122121111111111011111111211222222223221211111121321122112121122131211212213121122121112311222113211332221321212213111221132312233433424223241242312323113121122222222312313123231132313433332222112121122311313123122121113211221312112124121341212223212112111122211111111111121223312122222211213123131221211212121131110112312113131241211223123231131312312123232242312422123231121211222124231332312213112121132211112013241231221213122131221101112122121121321413124242231311223332222311312111232232411232211201121111122323322131132210111222200000011311132111100010112210022243636
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380                 400                 420                 440                 460                 480                 500                 520                 540                 560                 580                 600                 620                 640                 660                 680                 700                 720                 740                 760                 780                 800                 820                 840                 860                 880                 900                 920                 940                 960                 980

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MHYSVLPPEINSALIFAGAGSGPMLAAASAWDGLATELASAAVSFGSVTAGLVGGSWQGRSSVAMAAAAAPYAGWLAAAATQAEQAATQAQVMVAEFEAVRLAMVQPALVAANRSGLISLVISNLFGQNAPAIAAAEAAYEEMWALDVSAMAAYHSGASAVAVALPAFALPLRLPAGLAAGPAAVVTALTTAVGMPTFAGRAIAASLGLANVGGGNLGNANNGLGNIGNANLGNNNLGSGNFGSFNIGSANLGGNNIGIGNAGANNFGLANLGNLNTGFANAGIGNFGIANTGNNNIGNGLTGNNQIGIGGLNSGNGNVGLFNAGSANIGFFNSGNGNFGIGNSGNFSTGLFNPGHGNTGFLNAGSFNTGMFDVGNANTGSFNVGHYNFGAFNPGPSNTGTFNTGGANTGWFNTGSINTGAFNIGDMNNGLFNTGDMNNGVFYRGVGQGSLQFAITSPDLTLPSLEIPGISVPAFSLPAITLPSLTIPAVTTPANVTVGAFDLPGLTVPSLTIPAAMTPANITVGAFDLPGLTVPSLTIPATTTPANITVGAFNLPQLSIPSVTVPPITIPAGTALGAFNLPTLSIPSVTVPPITIPAGTTVGGFTLPTIHTPLISTPQISIGGFSTPGIATQANSGVINLPTFSLNGITITNLVVFIPNNITALQTNMPGVFPQIGGFANTPPAFINTGTITVGGGQINGVGFSIGAINVTPFTLPNVVIQPWSLGGISVDGFTLPEISTQEFTTPALTISPIGVGALSLPDITTQQFTTPELTIDPITLGGFTLPQLSIPAITTPAFTIDPIALGGFTLPQIMTPEITTPPFAIDPIGLSGFTLPQVNIPEITTPEFTIQPVGLAAFTTPALTIASIHLPSTTMGGFAIPAGPGYFNSSATPSLGFFNAGIGGNSGFGNSGSGLSGWFNTSPVGLLAGSGYQNYGGLISGFSNLGSGISGFANTGTLPFAVTSLVSGLANIGNNLSGLFFQSTTP

2g38B

0.30

0.05

0.18

2.50

wdPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSL-MDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3hr2A

0.10

0.09

0.86

2.73

dPPAS

----------------------------------------------------------------------------------------------------------------------------------------QMSYGYDEKSAGVSVPGPMGPSGPRGLGPGAGPQGFQGPGEGEGGSGPMGPPGPGPGKNGDDGEAGKPGRGERGPGPQGARGLGTAGLGMGHRGFSGLDGAKGDTGPAGPKGEGSGENGTGQMGPRGLGERGRGPGTAGARGNDGAVGAAGPGPTGPTGPGFGAAGAKGEAGPQGARGSEGPQGVRGEGPGPAGAAGPAGNGADGQGAKGANGAGIAGAGFGARGPSGPQGPSGAGPKGTSGEGAGNKGDTAKGEGPAGVQGPGPAGEEGKRGARGEGPSGLGPGERGGGSRGFGADGVAGPKGPSGERGSGPAGPKGSGEAGRGEAGLGAKGLTGSGSGPDGKTGPGPAGQDGRGPAGPGARGQAGVMGFGPKGTAGEGKAGERGVGPGAVGPAGKDGEAGAQGAGPAGPAGERGEQGPAGSGFQGLGPAGPGEAGKGEQGVGDLGAGPSGARGERGFGERGVQGPGPAGPRGNNGAGNDGAKGDTGAGAGSQGAGLQGMGERGAAGLGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPGPAGAGDKGEAGPSGPAGPTGARGAGDRGEAGPGPAGFAGPGADGQGAKGEGDTGVKGDAGPGPAGPAGPGPIGNVGAGPGSRGAAGPGATGFGAAGRVGPGPSGNAGPGPGPVGKEGGKGPRGETGPAGRGEVGPGPGPAGEKGSGADGPAGSGTPGPQGIAGQRGVVGLGQRGKRGFGLGPSGEGKQGPSGASGERGPGPMGPGLAGPGESGREGSGAEGSGRDGAGAKGDRGETGPAGPGAGAGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDGETGEQGDRGIGHRGFSGLQ

2g38B

0.30

0.05

0.18

3.40

wPPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSL-MDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3hr2A

0.09

0.08

0.86

3.82

dPPAS2

----------------------------------------------------------------------------------------------------------------------------------------QMSYGYDEKSAGVSVPGPMGPSGPRGLGPGAGPQGFQGPGEGEGGSGPMGPPGPGPGKNGDDGEAGKPGRGERGPGPQGARGLGTAGLGMGHRGFSGLDGAKGDTGPAGPKGEGSGENGTGQMGPRGLGERGRGPGTAGARGNDGAVGAAGPGPTGPTGPGFGAAGAKGEAGPQGARGSEGPQGVRGEGPGPAGAAGPAGNGADGQGAKGANGAGIAGAGFGARGPSGPQGPSGAGPKGTSGEGAGNKGDT--GAKGEGPAGVQGPGPAGEEGKRGARGEGPSGLGPGERGGGSRGFGADGVAGPKGPSGERGSGPAGPKGSGEAGRGEAGLGAKGLTGSGSGPDGKTGPGPAGQDGRGPAGPGARGQAGVMGFGPKGTAGEGKAGERGVGPGAVGPAGKDGEAGAQGAGPA-GPAGERGEQGPAGSGFQGLGPAGPGEAGKGEQGVGDLGAGPSGARGERGFGERGVQGPGPAGPRGNNGAGNDGAKGDTGAGAGSQGAGLQGMGERGAAGLGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPGPAGAGDKGEAGP-SGPAGPTGARGAGDRGEAGPGPAGFAGPGADGQGAKGEGDTGVKGDAGPGPAGPAGPGPIGNVGAGPGSRGAAGPGATGFGAAGRVGPGPSGNAGPGPGPVGKEGGKGPRGETGPAGRGEVGPGPGPAGEKGSGADGPAGSGTPGPQGIAGQRGVVGLGQRGKRGFGLGPSGEGKQGPSGASGERGPGPMGPGLAGPGESGREGSGAEGSGRDGAGAKGDRGETGPAGPGAGAGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDGETGEQGD--RGIGH

2g38B

0.30

0.05

0.18

2.92

Env-PPAS

-AFEAYPPEVNSANIYAGPGPDSMLAAARAWRSLDVEMTAVQRSFNRTLLSL-MDAWAGPVVMQLMEAAKPFVRWLTDLCVQLSEVERQIHEIVRAYEWAHHDMVPLAQIYNNRAERQILIDNNALGQFTAQIADLDQEYDDFWDEDGEVMRDYRLRVSDALSKLTPWKAPPPIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3hr2A

0.10

0.08

0.86

3.49

PPAS

----------------------------------------------------------------------------------------------------------------------------------------QMSYGYDEKSAGVSVPGPMGPSGPRGLGPGAGPQGFQGPGSGPMGPPGPGPGKNGDDGEAGKPGRGERGPGPQGARGLTAGLGMGHRGFSGLDGAKGDTGPAGPKGEGSGENGTGQMGPRGLGERGRGPGTAGARGNDGAVGAAGPGPTGPTGPGFGAAGAKGEAGPQGARGSEGPQGVRGEGPGPAGAAGPAGNGADGQGAKGANGAGIAGAGFGARGPSKGTSGEGAGNKGDTGAKGEGPAGVQGPGPAGEEGKRGARGEGPSGLGPGERGGGSRGFGADGVAGPKGPSGERGSGPAGPKGSGEAGRGEAGLGAKGLTGSGSGPDGKTGPGPAGQDGRGPAGPGARGQAGVMGFGPKGTAGEGKAGERGVGPGAVGPAGKDGEAGAQGAGPAGPAGEEQGPAGSGFQGLGPAGPGEAGKGEQGVGDLGAGPSGARGERGFGERGVQGPGPAGPRGNNGAGNDGAKGDTGAGAGSQGAGLQGMGERGAAGLGPKGDRGDAGPADGSPGKDGVRGLTGPIGPGPAGAGDKGEAGPSGPAGPTGARGAGDRGEAGPGPAGFAGPGADGQGAKGEGDTGVKGDAGPGPAGPAGPGPIGNVGAGPGSRGAAGPGATGFGAAGRVGPGPSGNAGPGPGPVGKEGGKGPRGETGPAGRGEVGPGPGPAGEKGSGADGPAGSGTPGPQGIAGQRGVVGLGQRGKRGFGLGPSGEGKQGPSGASGERGPGPMGPGLAGPGESGREGSGAEGSGRDGAGAKGDRGETGPAGPGAGAGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDGETGEQDRGIGHRGFSGLQGPGSGSGEQPRGPGSAGSGK

5ak1A

0.13

0.10

0.76

1.80

wMUSTER

PQRGR--PRLN-TTFVGDNGQ-PLPYTSTEWTA-YDQIARVKEGFNAVLYAECFDPRYSKAPGYAVNEIDKIVERTRELGHNAQWARDFWKFYAPRYENPPGAVDEIDVYRIIRTYTPVLLFSYAVFGGKGGAAEA---LKDIRAFNKAVFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFTEYAGGAWGSGGGLDVELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDYGNWPAARGVYGNGGLARETATWINNFLTGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQYRPDEGVDIEKTSDTGGGYNSEG--TIRVRNPGYYNLSLRVAGISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLRINALSGGFNLNWIELSPISTGTIPDGTYKFLNRANGKTLQEVTGNNSIITADYKGITEQHWKIQHIGGGQYRISSAGRG-WNWNWWGFGTVGWWGTGSSTCFIISPTGDGYYRIVLVGDGTNLQISSGDPSKIEGKAFHGGANQQWAILPVSAPAFPTGLSAVLDSSGNTLTWNAAPGANSYNVKRSTKSGGPYTTIATNITSTNYTDTGVATGTKVVSAVSNGVETLNSAEAILQYPKLTGTVIGTQGSWNNIGNTIHKAFDGDLNTFFDGPTANGCWLGLDFGEGVRNVITQIKFCPRSGYEQRIGGIFQGANKEDFSDAVTLFTITSLPGSGTLTSVDVDNPTGFR--LSPDGSNGNGTPAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5a1uE

0.08

0.06

0.83

1.98

MUSTER

------------------------------------------------------------------------------------------------------------------------------------------HLEKSAVQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHV-RKNDRLAVSKMISKFTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLEKALQQYTLEPSQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTEAYEVLSYVPARSLPYNQPGTCYTLVALPTEDPTAVACTFSCVMKFTVKDCDPNTGEIDEEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNI----VKFLGMHPCERSDKVPENKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG----------------------

3gavA

0.10

0.09

0.94

1.72

wMUSTER

LNPLRKPGDTPFGTFTLTGGN---------------EYGVKAV-YEINYRECDTDGWTND---------IP------------------------------VVKCLPVTAPEN----GKIVSSAMEPDREYHFGQA-VRFVKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENENMGYEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEGFYPATRGNTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSGYALPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFSESQYTYALKEKKLGYVTADGETSGSITCGKDGWSAQPT-CIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSIGHRSITCIHGVWTQLPQVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCSPPEISHGVVAHMSDSYQYGEEGPAIAEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQATYYKMDGASNVTSRWTGRPTCRDTSCVNPPTVQNAIVSRQMSKYPSGER-RSPYEMFGDEEVMCLNGNGDITSFPLSVYAPASSQNLYQLEGNKRIGIMENYNIALRWTAKQKLYSRTGESVEGYRLSSRSH

3hr2B

0.09

0.08

0.86

2.68

dPPAS

-----------------------------------------------------------------------------------------------------------------------------------------SDKGVSAGPGPMGLMGPRGPGAVGAGPQGFQGPAGEGEGQTGPAGSRGPAGPGKAGEDGHGKPGRGERGVVGPQGARGFGTGLGFGIGLDGLKGQGAQGVGEGAGENGTGQAGARGLGERGRVGAGPAGARGSDGSVGPVGPAGPIGSAGPGFGAGPGELGPVGNGPAGPAGPRGEAGLGLSGPVGPGNPGANGLTGAGATGLGVAGAGLGPRGIGPVGAAGATGPRGLVGEGPAGSGETGNKGEGSAGAQGPGPSGEEGKRGSPGEPGSAGPAGPGLRGSGSRGLGADGRAGVMGPPGNRGSTGPAGVRGPNGDAGRGEGLMGPRGLGSGNVGPAGKEGPVGLGIDGRGPIGPAGPRGEAGNIGFGPKGPSGDGKGEKGHPGLAGARGAGPDGNNGAQGPGPQGVQGGKGEQGPAGPGFQGLGPSGTAGEVGKGERGLPGEFGLGPAGPRGERGPGESGAAGPSGPIGIRGPSGAGPDGNKGEAGAVGAPGSAGASGPGGLGERGAAGIGGKGEKGETGLRGEIGNPGRDGARGAGAIGAGPAGASGDRGEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPAGSAGQGAGEKGTKGPKGENGIVGPTGPVGAAGPSGPNGPPGPAGSRGDGGPPGMTGFGAAGRTGPGPSGITGPGPGAAGKEGIRGPRGDQGPVGRTGEIGASGPPGFAGEKGPSGEGTTGPGTAGPQGLLGAGILGLGSRGERGQGIAGALGEGPLGIAGPGARGPGAVGSGVNGAGEAGRDGNGSDGPGRDGQGHKGERGYGNIGPTGAAGAPGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGD

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-2.39

Estimated TM-score = 0.43±0.14

Estimated RMSD = 15.0±3.5Å

Download Model 2

C-score=-2.51

Download Model 3

C-score=-3.33

Download Model 4

C-score=-3.49

Download Model 5

C-score=-3.46

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3hr2A	0.347	8.87	0.076	0.540
2	3hr2B	0.335	9.41	0.067	0.525
3	1sjjA	0.129	7.61	0.027	0.179
4	3cmuA	0.122	7.56	0.038	0.169
5	2eyqA	0.121	6.88	0.045	0.161
6	5a7mA1	0.116	6.38	0.045	0.152
7	3u48A	0.115	6.84	0.060	0.155
8	3p8cA	0.115	6.34	0.043	0.147
9	3hmjG	0.114	8.19	0.032	0.168
10	4o5pA	0.113	7.04	0.065	0.155

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.09	7	3cmvG	ANP	Rep, Mult	951,952,953,954,955,956
2	0.05	4	3cmvH	ANP	Rep, Mult	950,951,952
3	0.03	2	3cmvG	ANP	Rep, Mult	614,615,616,617
4	0.03	2	4xgcC	III	Rep, Mult	82,83
5	0.03	2	3iylA	MYR	Rep, Mult	330,341
6	0.03	2	4lqhA	MG	Rep, Mult	84,85
7	0.01	1	4afyA	NUC	Rep, Mult	95,96
8	0.01	1	3lziA	DTP	Rep, Mult	14,15,24,89
9	0.01	1	2j62A	GSZ	Rep, Mult	170,172
10	0.01	1	1xmvA	ADP	Rep, Mult	301,302,303,305
11	0.01	1	3mgrH	RB	Rep, Mult	101,102,104
12	0.01	1	2vn4A	MAN	Rep, Mult	344,345
13	0.01	1	3kd5E	PPF	Rep, Mult	266,267,268,269
14	0.01	1	3l68A	COU	Rep, Mult	60,64
15	0.01	1	3lw5K	CLA	Rep, Mult	83,87
16	0.01	1	2i36C	UUU	Rep, Mult	972,979
17	0.01	1	2oyqD	QNA	Rep, Mult	298,299,300,301
18	0.01	1	2p5gD	QNA	Rep, Mult	237,238,240,242,244,245
19	0.01	1	2rmpA	UUU	Rep, Mult	274,275,276,286
20	0.01	1	2o01H	CLA	Rep, Mult	116,120

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1q16A	0.110	7.24	0.053	0.152	1.7.99.4	NA
2	0.060	1iwpA	0.087	7.67	0.059	0.124	4.2.1.30	NA
3	0.060	2vkzG	0.113	8.14	0.038	0.167	2.3.1.38,3.1.2.14	NA
4	0.060	1q50A	0.077	5.90	0.035	0.097	5.3.1.9	NA
5	0.060	3b9jJ	0.062	5.58	0.023	0.076	1.17.1.4,1.17.3.2	NA
6	0.060	2uv8G	0.113	8.40	0.023	0.169	2.3.1.86	NA
7	0.060	1h0hA	0.110	7.20	0.065	0.153	1.2.1.2	NA
8	0.060	1ogyA	0.104	8.05	0.043	0.149	1.7.99.4	NA
9	0.060	2vz8A	0.106	7.96	0.019	0.155	2.3.1.85	NA
10	0.060	1frvB	0.105	6.13	0.064	0.134	1.12.2.1	NA
11	0.060	2jfdA	0.078	6.33	0.053	0.100	2.3.1.85	NA
12	0.060	2e1qA	0.103	7.14	0.017	0.142	1.17.3.2,1.17.1.4	NA
13	0.060	1ofdA	0.100	7.04	0.031	0.135	1.4.7.1	NA
14	0.060	1k32A	0.104	7.61	0.025	0.146	3.4.21.-	NA
15	0.060	1fo4A	0.093	8.43	0.022	0.138	1.17.1.4	NA
16	0.060	2x42A	0.113	6.88	0.029	0.150	3.2.1.21	NA
17	0.060	2v45A	0.109	6.45	0.029	0.144	1.7.99.4	NA
18	0.060	2o2dB	0.106	7.81	0.050	0.153	5.3.1.9	NA
19	0.060	2ckjA	0.087	7.97	0.018	0.125	1.17.1.4,1.17.3.2	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.06	0.372	7.55	0.06	0.52	3hqvB	GO:0005201 GO:0005576 GO:0005578 GO:0005581 GO:0030198 GO:0046872 GO:0071300 GO:0071310 GO:0071873 GO:0097067
1	0.06	0.362	7.76	0.07	0.52	3hqvA	GO:0001501 GO:0001503 GO:0001568 GO:0001649 GO:0001957 GO:0001958 GO:0005201 GO:0005576 GO:0005578 GO:0005581 GO:0005584 GO:0005615 GO:0005737 GO:0005783 GO:0005794 GO:0007584 GO:0007601 GO:0007605 GO:0009612 GO:0010718 GO:0010812 GO:0015031 GO:0030141 GO:0030198 GO:0030199 GO:0030335 GO:0031012 GO:0031667 GO:0031960 GO:0032355 GO:0032964 GO:0034504 GO:0034505 GO:0038063 GO:0042060 GO:0042493 GO:0042542 GO:0042802 GO:0043434 GO:0043588 GO:0043589 GO:0044344 GO:0044691 GO:0045893 GO:0046872 GO:0048407 GO:0048545 GO:0048705 GO:0048706 GO:0051591 GO:0055093 GO:0060325 GO:0060346 GO:0060351 GO:0070208 GO:0071230 GO:0071260 GO:0071300 GO:0071306 GO:0071356 GO:0071364 GO:0071560 GO:0090263 GO:1902617 GO:1902618
2	0.06	0.119	7.62	0.03	0.17	4d1eA	GO:0000165 GO:0002576 GO:0003779 GO:0005088 GO:0005178 GO:0005509 GO:0005546 GO:0005576 GO:0005737 GO:0005829 GO:0005856 GO:0005884 GO:0005886 GO:0005925 GO:0006936 GO:0007155 GO:0008092 GO:0008307 GO:0019904 GO:0030017 GO:0030018 GO:0030035 GO:0030049 GO:0030175 GO:0030274 GO:0030374 GO:0030375 GO:0030864 GO:0031093 GO:0031143 GO:0031432 GO:0042391 GO:0042802 GO:0042803 GO:0042981 GO:0043197 GO:0043267 GO:0043268 GO:0043547 GO:0044325 GO:0045214 GO:0046872 GO:0046983 GO:0048041 GO:0051015 GO:0051289 GO:0051373 GO:0051695 GO:0055013 GO:0070062 GO:0070080 GO:0086097 GO:0090002 GO:1901017 GO:1901018 GO:1903506 GO:2000009 GO:2000273 GO:2001137 GO:2001259
3	0.06	0.095	7.80	0.02	0.14	1g8xA	GO:0000146 GO:0000166 GO:0000281 GO:0000331 GO:0001931 GO:0003774 GO:0003779 GO:0005200 GO:0005509 GO:0005516 GO:0005524 GO:0005737 GO:0005773 GO:0005826 GO:0005829 GO:0005856 GO:0005884 GO:0005938 GO:0006909 GO:0006935 GO:0006971 GO:0006972 GO:0007275 GO:0008104 GO:0008360 GO:0009267 GO:0009612 GO:0016459 GO:0016460 GO:0030038 GO:0030554 GO:0030587 GO:0030674 GO:0030837 GO:0030866 GO:0030898 GO:0031034 GO:0031143 GO:0031152 GO:0031154 GO:0031252 GO:0031254 GO:0031270 GO:0031410 GO:0032009 GO:0032060 GO:0032154 GO:0032982 GO:0033275 GO:0033298 GO:0034461 GO:0042542 GO:0042641 GO:0042803 GO:0044351 GO:0045179 GO:0045335 GO:0046847 GO:0046872 GO:0048870 GO:0051015 GO:0051017 GO:0051764 GO:0060328 GO:0071889 GO:0097204 GO:1990753
4	0.06	0.101	7.11	0.04	0.14	4fn5A	GO:0000166 GO:0003746 GO:0003924 GO:0005525 GO:0005622 GO:0005737 GO:0006412 GO:0006414
5	0.06	0.084	7.86	0.03	0.12	4j5tA	GO:0003824 GO:0004573 GO:0005783 GO:0005789 GO:0006487 GO:0008152 GO:0009272 GO:0009311 GO:0016020 GO:0016021 GO:0016787 GO:0016798 GO:0070880
6	0.06	0.105	6.58	0.04	0.14	4pd3B	GO:0000146 GO:0000166 GO:0000281 GO:0000331 GO:0001701 GO:0001725 GO:0001764 GO:0001778 GO:0003279 GO:0003774 GO:0003779 GO:0005200 GO:0005509 GO:0005516 GO:0005524 GO:0005634 GO:0005737 GO:0005739 GO:0005773 GO:0005819 GO:0005829 GO:0005884 GO:0005886 GO:0005903 GO:0005938 GO:0006887 GO:0006909 GO:0006930 GO:0006972 GO:0007097 GO:0007155 GO:0007275 GO:0007409 GO:0007411 GO:0007420 GO:0007507 GO:0007512 GO:0008283 GO:0008360 GO:0009267 GO:0015629 GO:0016459 GO:0016460 GO:0021592 GO:0021670 GO:0021678 GO:0021680 GO:0030027 GO:0030036 GO:0030048 GO:0030239 GO:0030424 GO:0030426 GO:0030496 GO:0030587 GO:0030674 GO:0030898 GO:0031032 GO:0031175 GO:0031252 GO:0031410 GO:0031594 GO:0032154 GO:0035904 GO:0042641 GO:0042995 GO:0043005 GO:0043025 GO:0043197 GO:0043531 GO:0044351 GO:0045335 GO:0046872 GO:0048870 GO:0050885 GO:0051015 GO:0051017 GO:0051764 GO:0055003 GO:0055015 GO:0060041 GO:0060976 GO:0070062 GO:0097513
7	0.06	0.069	7.30	0.06	0.10	4i2yA	GO:0000086 GO:0000922 GO:0001975 GO:0002027 GO:0005246 GO:0005509 GO:0005513 GO:0005634 GO:0005737 GO:0005813 GO:0005819 GO:0005829 GO:0005856 GO:0005876 GO:0005886 GO:0006091 GO:0007190 GO:0008076 GO:0008179 GO:0008218 GO:0010880 GO:0018298 GO:0019722 GO:0019901 GO:0019904 GO:0021762 GO:0030017 GO:0030234 GO:0030235 GO:0030426 GO:0030801 GO:0031432 GO:0031800 GO:0031982 GO:0031996 GO:0031997 GO:0032465 GO:0032516 GO:0034704 GO:0035307 GO:0043005 GO:0043274 GO:0043388 GO:0043548 GO:0044325 GO:0046872 GO:0047485 GO:0048306 GO:0050998 GO:0051000 GO:0051343 GO:0051412 GO:0051592 GO:0055117 GO:0060314 GO:0060316 GO:0070062 GO:0072542 GO:1901339 GO:1901841
8	0.06	0.090	6.27	0.01	0.12	1pxyB	GO:0003779 GO:0005737 GO:0005856 GO:0007623 GO:0046872
9	0.06	0.078	5.85	0.00	0.10	1rt8A	GO:0000281 GO:0003779 GO:0005509 GO:0005737 GO:0005826 GO:0005856 GO:0006897 GO:0008360 GO:0030036 GO:0030437 GO:0030479 GO:0030674 GO:0030835 GO:0032432 GO:0046872 GO:0051015 GO:0051017 GO:0051666 GO:0051764 GO:0071963 GO:1903475
10	0.06	0.068	5.48	0.04	0.08	5bvrA	GO:0003779 GO:0005737 GO:0005826 GO:0005856 GO:0030036 GO:0030674 GO:0051017 GO:0051764 GO:1903475
11	0.06	0.075	5.86	0.03	0.09	4z6gA	GO:0003779 GO:0005509 GO:0005737 GO:0005794 GO:0005856 GO:0005874 GO:0005886 GO:0005913 GO:0007050 GO:0008017 GO:0010632 GO:0016020 GO:0016055 GO:0016887 GO:0030177 GO:0032587 GO:0032886 GO:0042060 GO:0042995 GO:0043001 GO:0044822 GO:0045773 GO:0046872 GO:0051015 GO:0051893 GO:0098609 GO:0098641
12	0.06	0.065	6.87	0.05	0.09	3u0kA	GO:0005509 GO:0006091 GO:0008218 GO:0046872
13	0.06	0.078	6.72	0.03	0.10	1xplA	GO:0003824 GO:0004421 GO:0008152 GO:0008299
14	0.06	0.052	6.19	0.04	0.07	4b7lB	GO:0001725 GO:0003334 GO:0003382 GO:0003779 GO:0005737 GO:0005829 GO:0005856 GO:0005886 GO:0005903 GO:0005913 GO:0005925 GO:0005938 GO:0007016 GO:0007165 GO:0007275 GO:0007517 GO:0007519 GO:0015629 GO:0016021 GO:0030018 GO:0030036 GO:0030154 GO:0031012 GO:0042802 GO:0044822 GO:0070062 GO:0098609 GO:0098641
15	0.06	0.072	5.38	0.04	0.09	1aoaA	GO:0003779 GO:0005509 GO:0005737 GO:0032420 GO:0042491 GO:0046872 GO:0060348
16	0.06	0.072	6.06	0.01	0.09	4q57B	GO:0003779 GO:0005737 GO:0005856 GO:0005903 GO:0005925 GO:0008092 GO:0008307 GO:0030054 GO:0030056 GO:0030506 GO:0031581 GO:0042383 GO:0043292 GO:0044822 GO:0045111 GO:0070062
17	0.06	0.105	7.48	0.03	0.15	2ycuA	GO:0000146 GO:0000166 GO:0000331 GO:0001725 GO:0003009 GO:0003774 GO:0003779 GO:0005200 GO:0005509 GO:0005516 GO:0005524 GO:0005737 GO:0005773 GO:0005829 GO:0005884 GO:0005903 GO:0005938 GO:0006909 GO:0006972 GO:0007275 GO:0007519 GO:0007605 GO:0008360 GO:0009267 GO:0016020 GO:0016459 GO:0016460 GO:0019228 GO:0030048 GO:0030424 GO:0030426 GO:0030587 GO:0030674 GO:0030898 GO:0031032 GO:0031252 GO:0031410 GO:0042641 GO:0043209 GO:0044351 GO:0045335 GO:0046872 GO:0048870 GO:0051015 GO:0051017 GO:0051764 GO:0070062 GO:0070584 GO:0071625 GO:0097513
18	0.06	0.083	7.17	0.07	0.12	4il1A	GO:0000082 GO:0000086 GO:0000922 GO:0001975 GO:0002027 GO:0004721 GO:0004722 GO:0004723 GO:0005246 GO:0005509 GO:0005513 GO:0005516 GO:0005634 GO:0005654 GO:0005737 GO:0005739 GO:0005813 GO:0005819 GO:0005829 GO:0005856 GO:0005876 GO:0005886 GO:0005955 GO:0006470 GO:0006606 GO:0006816 GO:0007190 GO:0008076 GO:0008144 GO:0008179 GO:0010880 GO:0014883 GO:0014898 GO:0016020 GO:0016311 GO:0016787 GO:0019722 GO:0019899 GO:0019901 GO:0019904 GO:0021762 GO:0030017 GO:0030018 GO:0030234 GO:0030235 GO:0030426 GO:0030801 GO:0031432 GO:0031800 GO:0031982 GO:0031996 GO:0031997 GO:0032465 GO:0032516 GO:0033173 GO:0033192 GO:0033555 GO:0034704 GO:0035307 GO:0035562 GO:0035690 GO:0042383 GO:0043005 GO:0043274 GO:0043388 GO:0043548 GO:0044325 GO:0045944 GO:0045955 GO:0046676 GO:0046872 GO:0046982 GO:0046983 GO:0047485 GO:0048306 GO:0048741 GO:0050774 GO:0050804 GO:0050998 GO:0051000 GO:0051091 GO:0051343 GO:0051412 GO:0051533 GO:0051592 GO:0055117 GO:0060079 GO:0060314 GO:0060316 GO:0070062 GO:0071333 GO:0072542 GO:0098794 GO:1901339 GO:1901841 GO:1903244

Consensus prediction of GO terms

Molecular Function	GO:0043169
GO-Score	0.46
Biological Processes	GO:0071300	GO:0042542	GO:0044344	GO:0038063	GO:1902618	GO:0031960	GO:0032355	GO:0045893	GO:0060346	GO:0001958	GO:0055093	GO:0071560	GO:0030335	GO:0048706	GO:0071873	GO:0071260	GO:0090263	GO:0097067	GO:0015031	GO:0007601	GO:0001649	GO:0010718	GO:0071356	GO:0051591	GO:0010812	GO:0042493	GO:0071364	GO:0001568	GO:0071230	GO:0001957	GO:0043589	GO:0060325	GO:0070208	GO:0060351	GO:0007605	GO:0032964	GO:0071306	GO:0034504	GO:0030199	GO:0042060	GO:0044691	GO:0034505	GO:0032060	GO:0031152	GO:0006935	GO:0048041	GO:0030866	GO:1901017	GO:0030038	GO:0044351	GO:2000009	GO:0031270	GO:0030049	GO:0090002	GO:1901018	GO:0031034	GO:0055013	GO:0060328	GO:2001137	GO:0002576	GO:0086097	GO:0006972	GO:0042391	GO:0051764	GO:2000273	GO:0043547	GO:0006414	GO:0030035	GO:0000165	GO:0006909	GO:0033298	GO:0000281	GO:0006971	GO:0030837	GO:0051289	GO:0045214	GO:0046847	GO:2001259	GO:0051695	GO:0034461	GO:0042981	GO:0031154	GO:0008360
GO-Score	0.12	0.12	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06	0.06
Cellular Component	GO:0044424
GO-Score	0.45

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
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