I-TASSER results

I-TASSER results for job id Rv1913

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (250 residues)
MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQV
THVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIA
ALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEES
ADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPR
ETPATLPCKR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
Prediction	CEEEEEEHCCCEEEEEHCCCCCEEEEEEHCCEEEEHCCCCCHHHHHHHHHHHHHHCCCCEEEEEHCCCCCCCCCHHHHHCCCCEEHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHCCEEEEHCCEEEEEEHCCCCCCCCCEEEEHCCCCCCCCCCEEEEHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
Conf.Score	9579999679989999589887799999699999997999999999999999998899868999689986446567875898599788899999886788999999875554567777666789857869879999999999999599999996899984556777887899855667788777799999999999999999869998699689999999999999999999999999999887799889
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
Prediction	6614345014201003133320000000155200112032327103301510472373402000000032000000310560401004401520563354224402522452352544144040343126623040361402021113210420000002434424543000000001131202023313172015004403623472324112434134372054015104412641365277525478
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CEEEEEEHCCCEEEEEHCCCCCEEEEEEHCCEEEEHCCCCCHHHHHHHHHHHHHHCCCCEEEEEHCCCCCCCCCHHHHHCCCCEEHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHCCEEEEHCCEEEEEEHCCCCCCCCCEEEEHCCCCCCCCCCEEEEHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR

3faiA

0.17

0.15

0.89

2.67

MUSTER

AGMSLTQVSGPVYVVEDYYVQENSMVYFGAKGVTVVGATWTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAGGNAYWKGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEYP----DLPLVLPNVVHDGDFTLQEGK--VRAFYAGPAHTPDGIFVYFPDE------QVLYGGCILK-EKLGNL-SFADVKAYPQTLERLKAMKLPIKTVIGGHDSPHGPELIDHYEALIKAAPQS-------------

1m2xA

0.16

0.13

0.84

4.01

dPPAS

-DVKIEKLKDNLYVYTTYKYAANAVYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGGAKTYSTKMTDSILAKEN----------------------KPRAQYTFDNNKSFKVGKSEFQVYYPGKGHTADNVVVWFPKE------KVLVGGCIIKSADSKDLGGEAYVNDWTQSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQ------------

1m2xA

0.16

0.13

0.83

3.83

wdPPAS

-DVKIEKLKDNLYVYTT-KYAANAVYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGGAKTYSTKMTDSILAKEN----------------------KPRAQYTFDNNKSFKVGKSEFQVYYPGKGHTADNVVVWFPK------EKVLVGGCIIKSADSKDLGGEAYVNDWTQSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQ------------

3faiA

0.18

0.16

0.89

3.35

wMUSTER

-GMSLTQVSGPVYVVEDYYVQENSMVYFGAKGVTVVGATWTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAGGNAYWKGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEY----PDLPLVLPNVVHDGD--FTLQEGKVRAFYAGPAHTPDGIFVYFPDE------QVLYGGCILKEK-LGNL-SFADVKAYPQTLERLKAMKLPIKTVIGGHDSPLGPELIDHYEALIKAAPQS-------------

1m2xA

0.16

0.13

0.83

3.65

wPPAS

-DVKIEKLKDNLYVYTT-KYAANAVYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGGAKTYSTKMTDSILAKEN----------------------KPRAQYTFDNNKSFKVGKSEFQVYYPGKGHTADNVVVWFPK------EKVLVGGCIIKSADSKDLGGEAYVNDWTQSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQ------------

1m2xA

0.16

0.13

0.84

4.82

dPPAS2

-DVKIEKLKDNLYVYTTYKYAANAVYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGGAKTYSTKMTDSILAKEN----------------------KPRAQYTFDNNKSFKVGKSEFQVYYPGKGHTADNVVVWFPKE------KVLVGGCIIKSADSKDLGGEAYVNDWTQSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQ------------

1m2xA

0.16

0.13

0.84

3.39

PPAS

-DVKIEKLKDNLYVYTTYKYAANAVYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGGAKTYSTKMTDSILAKEN----------------------KPRAQYTFDNNKSFKVGKSEFQVYYPGKGHTADNVVVWFPK------EKVLVGGCIIKSADSKDLGGEAYVNDWTQSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQ------------

2yntA

0.20

0.16

0.82

3.75

Env-PPAS

KPLEVIKIEDGVYLHTSFLVDSNGLVVLDNNQAYIIDTPWSEEDTKLLLSWATDR-GYQVMASISTHSHEDRTAGIKLLNSIPTYTSELTKKLLAREG-----------------------KPVPTHYFKDDEFTLGNGLIELYYPGAGHTEDNIVAWLPKSK------ILFGGCLVRSHEWEGLGGDASISSWADSIKNIVSKKYPIQMVVPGHGKVGSSDILDHTIDLAESASN--------------

1m2xA

0.16

0.13

0.84

2.60

MUSTER

-DVKIEKLKDNLYVYTTYKYAANAVYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGGAKTYSTKMTDSILAKEN----------------------KPRAQYTFDNNKSFKVGKSEFQVYYPGKGHTADNVVVWFPKEK------VLVGGCIIKSADSKDLGGEAYVNDWTQSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQ------------

3faiA

0.17

0.16

0.89

3.97

dPPAS

AGMSLTQVSGPVYVVEDYYVQENSMVYFGAKGVTVVGATWTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAGGNAYWKGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEYP----DLPLVLPNVVHDGDFTLQEGK--VRAFYAGPAHTPDGIFVYFPDEQ------VLYGGCILKEKLGNL--SFADVKAYPQTLERLKAMKLPIKTVIGGHDSPLGPELIDHYEALIKAAPQS-------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.74

Estimated TM-score = 0.81±0.09

Estimated RMSD = 4.3±2.9Å

Download Model 2

C-score=-3.76

Download Model 3

C-score=-4.35

Download Model 4

C-score=-3.61

Download Model 5

C-score=-1.62

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3faiA	0.839	1.59	0.175	0.892
2	3q6vA	0.829	1.46	0.132	0.876
3	2yheA	0.807	2.83	0.192	0.948
4	1znbB	0.803	1.51	0.192	0.852
5	2cg2A	0.801	2.91	0.146	0.944
6	4nurA	0.793	2.99	0.167	0.948
7	2fhxA	0.793	2.41	0.131	0.876
8	1m2xA	0.790	1.46	0.158	0.836
9	1ko3A	0.769	1.49	0.221	0.816
10	2yntA	0.769	1.65	0.184	0.824

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.63	255	5ewaB	9BZ	Rep, Mult	69,71,150,175,178,185,186,215
2	0.29	121	1wuoB	ZN	Rep, Mult	67,69,150,175
3	0.04	24	1x8gA	CO3	Rep, Mult	71,150,175,178,215
4	0.03	12	2bmiB	NA	Rep, Mult	22,23,37,71,172
5	0.02	14	1kr3A	113	Rep, Mult	150,175,178,186,215
6	0.02	11	3iofA	IFS	Rep, Mult	20,40,70,71,101,104,105,109,150,175,186,215
7	0.01	5	2fhxA	AZI	Rep, Mult	37,66,67,172,174,175
8	0.00	1	2y87A	MG	Rep, Mult	70,117
9	0.00	1	4gyuA	IMD	Rep, Mult	37,38,65,67,72
10	0.00	1	4ey2B	ZN	Rep, Mult	97,188
11	0.00	2	1jjeA	ZN	Rep, Mult	23,217
12	0.00	1	1vgn0	III	Rep, Mult	18,21,210,217,218,219,220,222,226
13	0.00	1	2bgaA	AZI	Rep, Mult	140,161
14	0.00	1	1bc20	III	Rep, Mult	183,184,186,187,191,192,230,231,232
15	0.00	1	1m2xA	ZN	Rep, Mult	226,229
16	0.00	1	2bflB	AZI	Rep, Mult	150,186
17	0.00	1	2cfzA	1DO	Rep, Mult	71,106,109,113,115,184
18	0.00	1	3f9oA	CO3	Rep, Mult	201,202,205,206,208
19	0.00	1	3f9oA	CO3	Rep, Mult	106,118

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.429	1l9yA	0.734	2.92	0.160	0.876	3.5.2.6	71
2	0.413	1qh3A	0.650	3.02	0.153	0.776	3.1.2.6	71
3	0.219	1a8tA	0.790	1.61	0.190	0.844	3.5.2.6	NA
4	0.193	2q42A	0.644	2.86	0.161	0.752	3.1.2.6	21,69,71
5	0.130	2qedA	0.625	3.05	0.137	0.744	3.1.2.6	73
6	0.107	1qh5A	0.651	2.98	0.153	0.776	3.1.2.6	NA
7	0.102	2p18A	0.681	3.03	0.167	0.812	3.1.2.6	71
8	0.071	1xm8A	0.645	2.84	0.167	0.752	3.1.2.6	71
9	0.060	1ko2A	0.766	1.54	0.221	0.816	3.5.2.6	NA
10	0.060	1znbB	0.803	1.51	0.192	0.852	3.5.2.6	152,215
11	0.060	2dkfA	0.581	4.05	0.144	0.772	3.1.-.-	73
12	0.060	2zo4A	0.740	3.16	0.190	0.896	3.-.-.-	NA
13	0.060	2cbnA	0.511	4.94	0.114	0.728	3.1.26.11	23,69,71
14	0.060	1x8hA	0.839	1.59	0.175	0.892	3.5.2.6	71
15	0.060	1zedA	0.439	5.68	0.067	0.720	3.1.3.1	148,228
16	0.060	2gmnA	0.722	3.29	0.167	0.888	3.5.2.6	71
17	0.060	2i7vA	0.571	4.32	0.090	0.776	3.1.27.-	71
18	0.060	1ayxA	0.409	6.16	0.039	0.712	3.2.1.3	NA
19	0.060	1smlA	0.731	3.19	0.152	0.888	3.5.2.6	71
20	0.060	3dhaA	0.629	3.16	0.167	0.744	3.1.1.-	71
21	0.060	2ohhA	0.736	3.16	0.188	0.892	1.-.-.-	71
22	0.060	1p9eA	0.678	3.79	0.170	0.848	3.1.8.1	NA
23	0.060	3hnnA	0.691	3.27	0.120	0.832	1.-.-.-	NA
24	0.060	1m2xA	0.790	1.46	0.158	0.836	3.5.2.6	71
25	0.060	1bvtA	0.766	1.57	0.211	0.816	3.5.2.6	NA
26	0.060	1ycfA	0.724	3.01	0.161	0.872	1.7.99.7	71

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.53	0.790	1.46	0.16	0.84	1m2xA	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0042597 GO:0046677 GO:0046872
1	0.52	0.740	3.16	0.19	0.90	2zo4A	GO:0046872
2	0.49	0.759	1.74	0.19	0.82	3l6nA	GO:0008270 GO:0008800 GO:0017001 GO:0046872
3	0.48	0.790	1.61	0.19	0.84	1a8tA	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0042597 GO:0046677 GO:0046872
4	0.47	0.635	3.58	0.13	0.79	2r2dA	GO:0016787 GO:0046872 GO:0102007
5	0.47	0.664	2.92	0.23	0.79	2zwrB	GO:0046872
6	0.41	0.836	1.48	0.13	0.88	3sd9A	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0046677 GO:0046872
7	0.39	0.761	1.58	0.23	0.81	4d1tA	GO:0008270 GO:0008800 GO:0017001 GO:0046872
8	0.38	0.621	3.83	0.17	0.78	3aj3A	GO:0016787 GO:0042820 GO:0046872 GO:0047585
9	0.38	0.839	1.59	0.17	0.89	3faiA	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0042597 GO:0046677 GO:0046872
10	0.38	0.755	1.96	0.17	0.82	4hl2A	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0042597 GO:0046677 GO:0046872
11	0.37	0.769	1.65	0.18	0.82	2yntA	GO:0046872
12	0.36	0.629	3.16	0.17	0.74	3dhaA	GO:0016787 GO:0046872 GO:0102007
13	0.35	0.747	1.80	0.21	0.81	2m5cA	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0042597 GO:0046677 GO:0046872
14	0.34	0.757	1.77	0.17	0.82	4wd6A	GO:0046872
15	0.33	0.758	1.83	0.18	0.82	4ubqA	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0046677 GO:0046872
16	0.32	0.839	2.09	0.14	0.92	4bp0A	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0046872
17	0.31	0.723	3.28	0.17	0.89	3lvzB	GO:0046872
18	0.28	0.765	1.75	0.17	0.82	5ev6B	GO:0008270 GO:0008800 GO:0016787 GO:0017001 GO:0042597 GO:0046677 GO:0046872
19	0.25	0.721	3.11	0.19	0.87	5axoA	GO:0046872
20	0.23	0.644	2.86	0.16	0.75	2q42A	GO:0004416 GO:0005506 GO:0005739 GO:0008270 GO:0016787 GO:0019243 GO:0046872
21	0.23	0.736	2.84	0.15	0.87	1e5dA	GO:0009055 GO:0010181 GO:0016491 GO:0022904 GO:0046872 GO:0055114
22	0.22	0.715	3.32	0.17	0.86	4ad9A	GO:0004521 GO:0005739 GO:0005759 GO:0008270 GO:0016787 GO:0046872 GO:0090502
23	0.17	0.801	2.93	0.15	0.94	5aijA	GO:0016787 GO:0042802 GO:0046872 GO:0046983
24	0.16	0.792	3.00	0.16	0.93	4pdxA	GO:0016787 GO:0018741 GO:0030288 GO:0046983

Consensus prediction of GO terms

Molecular Function	GO:0008270	GO:0008800	GO:0102007
GO-Score	0.88	0.88	0.47
Biological Processes	GO:0017001	GO:0046677
GO-Score	0.88	0.75
Cellular Component	GO:0042597
GO-Score	0.75

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.