Threading Zmax Znorm MUSTER 4.94 0.85 dPPAS 8.77 0.94 wdPPAS 8.46 0.91 wMUSTER 6.63 1.14 wPPAS 8.22 1.17 dPPAS2 15.21 1.45 PPAS 8.39 1.20 Env-PPAS 6.02 0.75 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=11538) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.89 0.49+-0.15 8.6+-4.5 5831 0.144 model2 -2.77 2781 0.060 model3 -3.24 2240 0.037 model4 -5.00 267 0.006 model5 -4.43 719 0.011 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).