Threading Zmax Znorm MUSTER 4.84 0.84 dPPAS 7.16 0.77 wdPPAS 7.65 0.82 wMUSTER 5.07 0.87 wPPAS 6.75 0.96 dPPAS2 10.60 1.01 PPAS 6.32 0.90 Env-PPAS 5.49 0.69 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=18549) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.12 0.28+-0.09 14.3+-3.8 2819 0.019 model2 -4.61 1707 0.012 model3 -4.83 1414 0.009 model4 -4.62 1828 0.012 model5 -5.00 849 0.007 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).