I-TASSER results

Input Sequence in FASTA format

>protein (186 residues)
MQPDAYPVRVRGDLDPALSRWQWLVKWFLAIPHYIVLFFLHVAAVVVTVIAFFAILFTGR
YPRTLFDFNVGVMRWRWRVAFYALSALGTDRYPPFSLQTKAEYPADLEVDYPERLSRGLV
LIKWWLLAIPHYLILAVFLSSGWRVFLIDPHDRVGIMWPSLLVILLLVAVVALLFTGRYP
IGLYNL

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MQPDAYPVRVRGDLDPALSRWQWLVKWFLAIPHYIVLFFLHVAAVVVTVIAFFAILFTGRYPRTLFDFNVGVMRWRWRVAFYALSALGTDRYPPFSLQTKAEYPADLEVDYPERLSRGLVLIKWWLLAIPHYLILAVFLSSGWRVFLIDPHDRVGIMWPSLLVILLLVAVVALLFTGRYPIGLYNL
Prediction	CCCCCCCEEEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
Conf.Score	999999689985788765579999999999999999999999999999999999998636895788888888999999999987765567899988899999867998679886655899999999999999999999865544344578887765555899999999999999857888765689
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 \| \| \| \| \| \| \| \| \| MQPDAYPVRVRGDLDPALSRWQWLVKWFLAIPHYIVLFFLHVAAVVVTVIAFFAILFTGRYPRTLFDFNVGVMRWRWRVAFYALSALGTDRYPPFSLQTKAEYPADLEVDYPERLSRGLVLIKWWLLAIPHYLILAVFLSSGWRVFLIDPHDRVGIMWPSLLVILLLVAVVALLFTGRYPIGLYNL
Prediction	865743325143524561420101121213321331233133233212331321000004214301410001020212023213310221421214255576230404163264042000222121133223110001123313222344443332323201100133213110111432433276
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180

                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCEEEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MQPDAYPVRVRGDLDPALSRWQWLVKWFLAIPHYIVLFFLHVAAVVVTVIAFFAILFTGRYPRTLFDFNVGVMRWRWRVAFYALSALGTDRYPPFSLQTKAEYPADLEVDYPERLSRGLVLIKWWLLAIPHYLILAVFLSSGWRVFLIDPHDRVGIMWPSLLVILLLVAVVALLFTGRYPIGLYNL

4q2eA

0.11

0.09

0.82

1.39

dPPAS2

LEMK-----------ERDARFFYVILLALYPVLYGLVFEEPTQPLSILFITGVVFSLITDKDPSQVFKTVAAFSIALIYVTFFLSFFL-------PIYRDF----------------GAANALLVLTSTWVFDSFAYFTGLKFGRTRISPRYSPRKVIGGFLGVVIYTFLYRLVVNDLLSVNVICF

2mawA

0.11

0.08

0.69

1.30

dPPAS2

-----------------------------EEELYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPSTSDSSP---------------------------SIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGEGGGEGIDRLCLMAFSVFTIICTIGPNFVEE-

4bwzA2

0.13

0.12

0.94

0.79

MUSTER

--------RLKD----AVGKEAFLVAVLGVALPFLGGYLYGLEITLPALFLGTALVATSVLSRPYSRIILGAAVIDDVLGLIVLACVNGVAETGQELSALASPVVLVAGTVVTVIAILGKVLGGFLGALTQGVRSALTVGCGMAPRGEALGLKAGAVNEEEYAIVLFMVVFTTLFAPFALKPLIAW

2mawA

0.11

0.08

0.69

0.76

dPPAS

-----------------------------EEELYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPSTSDSSP---------------------------SIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGEGGGEGIDRLCLMAFSVFTIICTIGPNFVEE-

2mawA

0.12

0.08

0.66

0.76

wdPPAS

-------------------EEELYYGLNLLIPCVLISALALLVFLLEKISLGITVLLS----LTVFMLLVAEI--------------------PSTSDSSP-------------------SIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGEGGGEGIDRLCLMAFSVFTIICTIGPNFVEE-

3jd8A

0.15

0.13

0.87

0.82

wMUSTER

INGSAYRVFPYSVF-LTIIDDTIFNLGVSLGAIFLVTMVLLWSAVIMCATIAMVLVNMF-ISLNAVSLVNLVMSCGISVEFCSHITRA------FTVSMKGS-----------RVERAEEALAHMGSSVFSGITLTKFGGIVVLA-FAKSQIFQIFYFRMYLAMVLLGATHGLIFL---P-VLLSY

4tq3A1

0.14

0.09

0.67

0.85

wPPAS

------------------SKYLRLLR-----PVAWLCFLLPYAVGFGFGI--------TPNASLQHAVLGLLSFAFWMAFSFTINAL-VDRLHD--GLNLSMQP-------VTEISVREAWLYCIAFLALSLATAAAI-------------------NEKFFLAMLGANIIGYVYS--APWPVMDV

4or2A2

0.09

0.06

0.72

1.26

dPPAS2

------------------------------VIESIIAIAFSCLGILVTLFVTLIFVLY-RDTPVVKSSSRELCYIILAGIFLGYVCP-------FTLIAKP--------------TTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILARKPRFMSAIIASILISVQLTLVVTLIIMEPPMPILS

4ri2A

0.11

0.94

0.86

PPAS

-AKAPKKVE---KPKLKVEDGLFGTSGGIG--TKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEPLLLFFILFTLLGAIGALGDRGRFVDEP-----TFGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGT-GKFITDD

1lw1A

0.13

0.12

0.88

0.79

Env-PPAS

---------IEKAALPEYAKDIKLNLSSITRQEQLWGTLLASAAATPQVLADIGAEATDHLAAARHAALGAAAIMGMNNVFYRGRGFLEGRY--------DDLRPGLRMNIIANPGIPKANFELWSFAVSAINGCSHCLVAFEHTLRTVGVDREAIFEALKAAAIVSGVAQALATIEASPS-----

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-3.81

Estimated TM-score = 0.30±0.10

Estimated RMSD = 14.3±3.8Å

Download Model 2

C-score=-3.87

Download Model 3

C-score=-4.46

Download Model 4

C-score=-4.82

Download Model 5

C-score=-4.87

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2bg9E	0.594	3.75	0.021	0.763
2	2bg9A	0.591	3.64	0.056	0.763
3	2d4yA	0.590	3.95	0.059	0.806
4	2bg9B	0.588	3.63	0.049	0.753
5	4pirA	0.567	3.51	0.078	0.710
6	4cofA	0.566	3.16	0.027	0.710
7	3rhwA	0.564	3.41	0.065	0.715
8	3nzzA	0.563	4.64	0.061	0.839
9	2j0oA	0.559	4.56	0.043	0.839
10	2d4xA	0.557	4.09	0.061	0.785

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.07	4	1ow6C	III	Rep, Mult	36,39,40,43,81,84,85
2	0.05	3	4d2dA	78N	Rep, Mult	45,48,51,52,55,163
3	0.05	3	3luhB	5GP	Rep, Mult	74,78
4	0.05	3	5is0C	6ET	Rep, Mult	81,122,129
5	0.05	3	1cbkA	SO4	Rep, Mult	63,74,75,78
6	0.04	2	4y3bA	49F	Rep, Mult	33,36,37,122
7	0.04	2	1dxoA	DQN	Rep, Mult	92,111,175
8	0.04	2	3rifB	IVM	Rep, Mult	40,41,42,45,46,49
9	0.02	1	3ri5E	IVM	Rep, Mult	36,37,40,41,43,44
10	0.02	1	4ev6E	MG	Rep, Mult	43,129
11	0.02	1	3oc4B	FAD	Rep, Mult	92,93
12	0.02	1	1uduB	MG	Rep, Mult	90,176
13	0.02	1	3riaD	IVM	Rep, Mult	74,78,127,130,131,134,138
14	0.02	1	3vh7E	MG	Rep, Mult	30,33

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2p3gX	0.433	5.37	0.018	0.720	2.7.11.1	NA
2	0.060	3gehA	0.521	4.47	0.037	0.769	3.6.-.-	NA
3	0.060	1jtnA	0.269	5.61	0.014	0.484	3.2.1.17	NA
4	0.060	1bdgA	0.470	4.58	0.065	0.715	2.7.1.1	20
5	0.060	1ct9A	0.486	4.97	0.048	0.774	6.3.5.4	NA
6	0.060	1occA	0.454	5.06	0.078	0.726	1.9.3.1	NA
7	0.060	2ozaA	0.480	5.51	0.024	0.806	2.7.11.1,2.7.11.24	NA
8	0.060	3cxhN	0.473	4.84	0.043	0.763	1.10.2.2	95,97
9	0.060	1hxgA	0.501	4.52	0.043	0.742	4.2.3.9,4.1.99.7	NA
10	0.060	1wmwA	0.487	4.48	0.071	0.710	2.5.1.-	NA
11	0.060	1ig8A	0.365	4.94	0.088	0.570	2.7.1.1	NA
12	0.060	2frvD	0.489	5.26	0.051	0.785	1.12.2.1	31,40,76
13	0.060	1qhaA	0.510	5.10	0.054	0.828	2.7.1.1	NA
14	0.060	3i9wA	0.475	3.74	0.041	0.661	2.7.13.3	54,144
15	0.060	1frvB	0.474	5.08	0.098	0.763	1.12.2.1	NA
16	0.060	2ewgA	0.478	4.84	0.034	0.763	2.5.1.10	NA
17	0.060	1cc1L	0.482	4.88	0.071	0.790	1.12.99.6	113
18	0.060	2nztA	0.434	4.83	0.033	0.694	2.7.1.1	NA
19	0.060	1j36A	0.470	4.57	0.088	0.677	3.4.15.1	5

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.19	0.544	2.46	0.07	0.64	1oedA	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
1	0.18	0.575	3.66	0.09	0.75	4aq5E	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
2	0.16	0.556	2.94	0.11	0.68	2mawA	GO:0000187 GO:0001540 GO:0001666 GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0005892 GO:0006810 GO:0006811 GO:0006816 GO:0006874 GO:0007165 GO:0007271 GO:0007613 GO:0008284 GO:0015276 GO:0015464 GO:0015643 GO:0016020 GO:0016021 GO:0017081 GO:0022848 GO:0030054 GO:0032720 GO:0034220 GO:0035094 GO:0042166 GO:0042803 GO:0045202 GO:0045211 GO:0045766 GO:0050890 GO:0098655 GO:0099565
3	0.14	0.550	2.31	0.07	0.64	1oedB	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
4	0.14	0.551	2.36	0.02	0.64	1oedE	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
5	0.11	0.532	2.50	0.07	0.63	1oedC	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
6	0.11	0.499	3.46	0.09	0.67	2ksrA	GO:0001508 GO:0001661 GO:0001666 GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0005892 GO:0006810 GO:0006811 GO:0006816 GO:0006939 GO:0007165 GO:0007271 GO:0007274 GO:0007601 GO:0007605 GO:0007612 GO:0007613 GO:0007626 GO:0008144 GO:0008306 GO:0008542 GO:0009897 GO:0014059 GO:0015276 GO:0015464 GO:0016020 GO:0016021 GO:0019233 GO:0021562 GO:0021631 GO:0021771 GO:0021952 GO:0021955 GO:0030054 GO:0030890 GO:0032225 GO:0032226 GO:0033603 GO:0035094 GO:0035095 GO:0035176 GO:0042053 GO:0042113 GO:0042166 GO:0042220 GO:0042320 GO:0042391 GO:0045188 GO:0045202 GO:0045211 GO:0045471 GO:0045759 GO:0046982 GO:0048814 GO:0050877 GO:0050890 GO:0051291 GO:0051899 GO:0051963 GO:0060084 GO:0098655 GO:0099565
7	0.10	0.529	3.13	0.08	0.66	2lm2A	GO:0001508 GO:0001661 GO:0001666 GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0005892 GO:0006810 GO:0006811 GO:0006816 GO:0006939 GO:0007165 GO:0007271 GO:0007274 GO:0007601 GO:0007605 GO:0007612 GO:0007613 GO:0007626 GO:0008144 GO:0008306 GO:0008542 GO:0009897 GO:0014059 GO:0015276 GO:0015464 GO:0016020 GO:0016021 GO:0019233 GO:0021562 GO:0021631 GO:0021771 GO:0021952 GO:0021955 GO:0030054 GO:0030890 GO:0032225 GO:0032226 GO:0033603 GO:0035094 GO:0035095 GO:0035176 GO:0042053 GO:0042113 GO:0042166 GO:0042220 GO:0042320 GO:0042391 GO:0045188 GO:0045202 GO:0045211 GO:0045471 GO:0045759 GO:0046982 GO:0048814 GO:0050877 GO:0050890 GO:0051291 GO:0051899 GO:0051963 GO:0060084 GO:0098655 GO:0099565
8	0.10	0.571	3.64	0.04	0.75	4aq5A	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
9	0.10	0.554	3.63	0.06	0.73	4aq5C	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
10	0.10	0.549	3.48	0.10	0.71	4pirC	GO:0004889 GO:0004993 GO:0005230 GO:0005232 GO:0005886 GO:0005892 GO:0006810 GO:0006811 GO:0007210 GO:0007271 GO:0015276 GO:0015464 GO:0016020 GO:0016021 GO:0022850 GO:0030054 GO:0034220 GO:0042166 GO:0045202 GO:0045211 GO:0051378 GO:0098655 GO:1904602
11	0.08	0.478	3.52	0.09	0.64	2llyA	GO:0001508 GO:0001666 GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0005892 GO:0006281 GO:0006810 GO:0006811 GO:0006816 GO:0006979 GO:0007165 GO:0007268 GO:0007271 GO:0007274 GO:0007585 GO:0007626 GO:0009897 GO:0014059 GO:0015276 GO:0015464 GO:0016020 GO:0016021 GO:0019233 GO:0030054 GO:0030425 GO:0034220 GO:0035094 GO:0035095 GO:0035640 GO:0042113 GO:0042166 GO:0042391 GO:0043025 GO:0045202 GO:0045211 GO:0050877 GO:0050890 GO:0051899 GO:0060080 GO:0098655
12	0.08	0.502	3.49	0.09	0.68	4z90A	GO:0005230 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0034220
13	0.07	0.593	3.49	0.07	0.75	4aq5B	GO:0004889 GO:0005216 GO:0005230 GO:0005886 GO:0006810 GO:0006811 GO:0016020 GO:0016021 GO:0030054 GO:0034220 GO:0045202 GO:0045211 GO:0098655
14	0.07	0.567	3.68	0.04	0.74	3jafA	GO:0005230 GO:0005254 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006821 GO:0007218 GO:0007417 GO:0008270 GO:0016020 GO:0016021 GO:0016594 GO:0016934 GO:0022824 GO:0030054 GO:0030425 GO:0034220 GO:0034707 GO:0042995 GO:0043200 GO:0043204 GO:0045202 GO:0045211 GO:0045664 GO:0046872 GO:0051260 GO:0060012 GO:0071230 GO:0071294 GO:0071361 GO:0099565 GO:1902476
15	0.07	0.555	3.81	0.08	0.74	4tnwA	GO:0005230 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0008068 GO:0016020 GO:0016021 GO:0016595 GO:0030054 GO:0031987 GO:0045202 GO:0045211 GO:0051259 GO:1902476
16	0.07	0.546	3.55	0.07	0.70	4ireB	GO:0005230 GO:0005267 GO:0005272 GO:0005886 GO:0006810 GO:0006811 GO:0006813 GO:0006814 GO:0016020 GO:0016021 GO:0035725 GO:0071805
17	0.07	0.566	3.16	0.03	0.71	4cofA	GO:0004890 GO:0005216 GO:0005230 GO:0005254 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006821 GO:0007165 GO:0007605 GO:0016020 GO:0016021 GO:0022851 GO:0030054 GO:0034220 GO:0034707 GO:0043523 GO:0043524 GO:0045202 GO:0045211 GO:0048666 GO:0060021 GO:0060080 GO:0060119 GO:0060384 GO:0071420 GO:0090102 GO:1901215 GO:1902476 GO:1902711
18	0.07	0.541	3.56	0.07	0.71	4yeuA	GO:0005230 GO:0005267 GO:0005272 GO:0005886 GO:0006810 GO:0006811 GO:0006813 GO:0006814 GO:0016020 GO:0016021 GO:0034220 GO:0035725 GO:0071805

Consensus prediction of GO terms

Molecular Function	GO:0004889	GO:0046983	GO:0042277	GO:0042165	GO:0016247	GO:0042802	GO:0070405	GO:0015464	GO:0022824
GO-Score	0.58	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31
Biological Processes	GO:0098655	GO:1904018	GO:0032680	GO:0014070	GO:0006950	GO:0045765	GO:0006875	GO:1905114	GO:0036293	GO:0055074	GO:0043279	GO:0007268	GO:0070838	GO:0043406	GO:0007611	GO:0042127	GO:0072503	GO:0032147	GO:1903556
GO-Score	0.58	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31	0.31
Cellular Component	GO:0045211	GO:0030054	GO:0034702	GO:0005887	GO:0098802
GO-Score	0.58	0.58	0.31	0.31	0.31

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv1888c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]