Threading Zmax Znorm MUSTER 5.42 0.94 dPPAS 8.66 0.93 wdPPAS 8.80 0.95 wMUSTER 5.99 1.03 wPPAS 8.46 1.21 dPPAS2 17.02 1.62 PPAS 8.33 1.19 Env-PPAS 7.54 0.94 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=15546) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.23 0.56+-0.15 6.5+-3.9 10610 0.265 model2 -4.01 716 0.016 model3 -2.81 2247 0.055 model4 -4.32 367 0.012 model5 -4.07 361 0.015 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).