I-TASSER results

I-TASSER results for job id Rv1841c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (345 residues)
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAML
TGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVP
KNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAE
LSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGV
EQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLAD
ALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
Prediction	CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHCCCEEEEEHCCCCCCCCCHHHHHHHHHHCCCCEEEEHCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEHCCCCEEEEEHHHHHHHHHHCCCCCCCCC
Conf.Score	979999999999999999999999999984699999999989989999999998667889999998999999999999999999999999875887689999999999999999986556678987689999999899999999999999999999999999998988877766899999999999999989999999999997764788656444456885899988788889999999999998699867876899978998868889987656889998997557765689999999999999989959999958998776554899999996877788889
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 280 300 320 340 \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| \| MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR
Prediction	332323222112022312131012200020344204510763352041024017305300000011101000212310000003102310331412311010201122132002201320011012200210120033011203212220221123022002002041465454422350033005204643413750251032003066240430111143010020323467220430152037261000002246320000000010032246665140340023001014514045005403755210000000333200100121000000210421338
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHCCCEEEEEHCCCCCCCCCHHHHHHHHHHCCCCEEEEHCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEHCCCCEEEEEHHHHHHHHHHCCCCCCCCC
MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAMLTGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVPKNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAELSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGVEQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLADALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR

3oi8A

0.26

0.11

0.44

1.52

MUSTER

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKY-FNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.44

4.52

dPPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNVLKE-------NDSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKYF-NPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.44

4.63

wdPPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKYF-NPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.43

1.95

wMUSTER

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKY-FNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.44

2.33

wPPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKYF-NPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.44

7.21

dPPAS2

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKYF-NPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.44

2.11

PPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKYF-NPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3oi8A

0.26

0.11

0.44

3.48

Env-PPAS

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNASAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEVRDAITRSRNV--LKEN-----DSIERITAYVIDTAHSRFPVIGEDDEVLGILHAKDLLKYF-NPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNH-AIVIDEYGGTSGLVTFEDIIE------------

3ocmA

0.22

0.09

0.42

1.36

MUSTER

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AFG-VEERNVSGVLTLAERSIRS-ITPRTDVSWVNI-----DDDAATIRQQLTAAPHSFFPVCRGSDEVVGIGRAKDLVADLITEGRVR-RNRLRDPIIVHESIGILR-LDTLKRSRGQLVLVADEFGAIEGLVTPIDVFEAIAGEFPDEDEL

3lv9A

0.23

0.08

0.37

4.00

dPPAS

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEFEEKKIREI-VPRTDVCIYESD------SEEKILAILKEEGVTRYPVCRKNDDILGFVHIRDLYNQKINENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEEIVGEI------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-4.23

Estimated TM-score = 0.27±0.08

Estimated RMSD = 17.2±2.7Å

Download Model 2

C-score=-4.32

Download Model 3

C-score=-4.62

Download Model 4

C-score=-4.39

Download Model 5

C-score=-4.76

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3orgA	0.453	5.05	0.110	0.629
2	2ooxE	0.431	4.55	0.106	0.554
3	2v9jE	0.425	4.45	0.152	0.542
4	2qlvC	0.421	4.25	0.138	0.530
5	2j5wA	0.420	6.78	0.075	0.710
6	3oi8A	0.420	1.62	0.252	0.438
7	4a01A	0.410	6.30	0.045	0.643
8	4yzwA	0.408	6.66	0.088	0.678
9	3wkyA	0.404	6.76	0.066	0.693
10	3kh5A	0.403	4.29	0.128	0.504

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.56	35	4eagC	ATP	Rep, Mult	218,224,249,250,251,253,311,312,325,327,328,329,330
2	0.06	5	3kh5A	ADP	Rep, Mult	251,264,266,268,269,286,289,290,310,311,312
3	0.01	1	2y94E	III	Rep, Mult	255,257,260,289,291,315,319,321,322
4	0.01	1	3b2xA	NA	Rep, Mult	63,64,65,66,69

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	1gq2A	0.369	6.64	0.058	0.620	1.1.1.40	NA
2	0.060	3n2oA	0.371	6.08	0.049	0.586	4.1.1.19	135,300
3	0.060	1gpeA	0.374	6.56	0.066	0.620	1.1.3.4	NA
4	0.060	2fqfA	0.346	7.10	0.066	0.617	1.-.-.-	NA
5	0.060	2o36A	0.386	6.64	0.021	0.658	3.4.24.15	300
6	0.060	3b9jI	0.171	5.43	0.046	0.252	1.17.1.4,1.17.3.2	68,116
7	0.060	1fo4A	0.361	6.75	0.054	0.615	1.17.1.4	NA
8	0.060	3hhsA	0.402	6.62	0.064	0.670	1.14.18.1	NA
9	0.060	1ofdA	0.355	6.61	0.039	0.597	1.4.7.1	NA
10	0.060	3ig5A	0.394	6.45	0.052	0.638	6.3.2.2	310
11	0.060	1o0sA	0.371	6.54	0.040	0.615	1.1.1.38	NA
12	0.060	1galA	0.366	6.58	0.066	0.609	1.1.3.4	NA
13	0.060	1ea0A	0.329	6.80	0.031	0.565	1.4.1.13	NA
14	0.060	1asqA	0.357	7.08	0.049	0.641	1.10.3.3	326
15	0.060	3hhsB	0.403	6.67	0.061	0.672	1.14.18.1	NA
16	0.060	2vdcF	0.390	7.12	0.033	0.690	1.4.1.13	NA
17	0.060	1cf3A	0.366	6.35	0.048	0.603	1.1.3.4	NA
18	0.060	1llwA	0.382	6.99	0.056	0.672	1.4.7.1	NA
19	0.060	1gpeB	0.369	6.60	0.031	0.615	1.1.3.4	63,70,332

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.20	0.337	2.04	0.29	0.36	3lfrB	GO:0000166 GO:0003824 GO:0016614 GO:0050660 GO:0055114
1	0.13	0.408	4.10	0.10	0.50	3ddjA	GO:0000166 GO:0003824
2	0.12	0.320	2.82	0.23	0.36	2j9lC	GO:0000139 GO:0000166 GO:0005216 GO:0005247 GO:0005254 GO:0005524 GO:0005765 GO:0005768 GO:0005794 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006821 GO:0007588 GO:0010008 GO:0015297 GO:0016020 GO:0016021 GO:0031404 GO:0034220 GO:0045177 GO:0055085 GO:1902476 GO:1903959
3	0.10	0.426	4.35	0.17	0.54	2v8qE	GO:0000166 GO:0004679 GO:0005524 GO:0005654 GO:0006468 GO:0006629 GO:0006631 GO:0006633 GO:0016208 GO:0019901 GO:0031588 GO:0042304 GO:0043234 GO:0043531 GO:0050790 GO:0051291
4	0.10	0.402	4.34	0.12	0.50	3lfzA
5	0.09	0.317	2.55	0.20	0.35	3kpcA	GO:0003824
6	0.08	0.431	4.55	0.11	0.55	2ooxE	GO:0000166 GO:0003824 GO:0005524 GO:0005634 GO:0005737 GO:0005829 GO:0005975 GO:0006351 GO:0006355 GO:0006357 GO:0007165 GO:0016208 GO:0030295 GO:0031588 GO:0032147
7	0.07	0.316	3.58	0.11	0.38	3k6eB
8	0.06	0.420	4.31	0.14	0.53	3tdhC	GO:0000166 GO:0001302 GO:0003824 GO:0004679 GO:0005524 GO:0005634 GO:0005641 GO:0005737 GO:0005886 GO:0005975 GO:0006351 GO:0006355 GO:0006357 GO:0006468 GO:0007031 GO:0031588 GO:0043539 GO:0045722 GO:0071902
9	0.06	0.371	4.08	0.16	0.46	4qfsC	GO:0000166 GO:0004679 GO:0005524 GO:0005654 GO:0006468 GO:0006629 GO:0006631 GO:0006633 GO:0016208 GO:0019901 GO:0031588 GO:0042304 GO:0043234 GO:0043531 GO:0050790 GO:0051291
10	0.06	0.375	4.03	0.10	0.47	2yzqA	GO:0003824 GO:0046872 GO:0051536 GO:0051539
11	0.06	0.358	6.74	0.06	0.61	4uvmA	GO:0005215 GO:0006810 GO:0006857 GO:0015197 GO:0015833 GO:0016020 GO:0016021
12	0.06	0.453	5.05	0.11	0.63	3orgA
13	0.06	0.296	6.88	0.04	0.52	3nd0A	GO:0005216 GO:0005247 GO:0006821 GO:0016020 GO:0016021 GO:0034220 GO:0055085 GO:1903959
14	0.06	0.332	6.83	0.05	0.57	1kplB	GO:0005216 GO:0005247 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006821 GO:0015108 GO:0015297 GO:0016020 GO:0016021 GO:0034220 GO:0055085 GO:1902476 GO:1903959
15	0.06	0.319	7.09	0.06	0.57	3updA	GO:0004585 GO:0005737 GO:0006520 GO:0006526 GO:0006591 GO:0008652 GO:0016597 GO:0016740 GO:0016743
16	0.06	0.336	4.97	0.08	0.45	4l3vA	GO:0003824 GO:0004122 GO:0004124 GO:0005634 GO:0005737 GO:0005829 GO:0006535 GO:0006563 GO:0006565 GO:0008152 GO:0008652 GO:0016829 GO:0019343 GO:0019344 GO:0019346 GO:0019448 GO:0019825 GO:0019899 GO:0020037 GO:0030170 GO:0031625 GO:0042262 GO:0042802 GO:0042803 GO:0043418 GO:0046872 GO:0050421 GO:0050667 GO:0055114 GO:0070025 GO:0070026 GO:0070814 GO:0072341 GO:1904047
17	0.06	0.320	2.43	0.15	0.35	4fryB	GO:0000166
18	0.06	0.326	6.57	0.07	0.55	1kpkA	GO:0005216 GO:0005247 GO:0005886 GO:0005887 GO:0006810 GO:0006811 GO:0006821 GO:0015108 GO:0015297 GO:0015299 GO:0015706 GO:0016020 GO:0016021 GO:0031404 GO:0043168 GO:0055085 GO:1902476 GO:1902600 GO:1903959

Consensus prediction of GO terms

Molecular Function	GO:0032550	GO:0035639	GO:0032559	GO:0016491	GO:0050662
GO-Score	0.42	0.42	0.42	0.40	0.40
Biological Processes	GO:0044710
GO-Score	0.40
Cellular Component	GO:0005887	GO:0045177	GO:0005765	GO:0000139	GO:0010008	GO:0031588	GO:0005654
GO-Score	0.12	0.12	0.12	0.12	0.12	0.10	0.10

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.